ChemicalBook > CAS DataBase List > 6-Chloro-4-pyrimidinecarboxylic acid

6-Chloro-4-pyrimidinecarboxylic acid

Product Name
6-Chloro-4-pyrimidinecarboxylic acid
CAS No.
37131-91-2
Chemical Name
6-Chloro-4-pyrimidinecarboxylic acid
Synonyms
6-Chlor-pyrimidin-4-carbonsaeure;4-Chloro-6-pyrimidinecarboxylic acid;6-chloropyrimidine-4-carboxylic acid;6-Chloro-4-pyrimidinecarboxylic acid;6-Chloro-pyrimidin-4-carboxylic acid;4-PyriMidinecarboxylic acid, 6-chloro-;6-Chloropyrimidine-4-carboxylic acid 97%;6-Chloro-4-pyrimidinecarboxylic acid ISO 9001：2015 REACH
CBNumber
CB81501553
Molecular Formula
C5H3ClN2O2
Formula Weight
158.54
MOL File
37131-91-2.mol
More
Less

6-Chloro-4-pyrimidinecarboxylic acid Property

Boiling point:
343.7±22.0 °C(Predicted)
Density 
1.579±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
2.44±0.10(Predicted)
Appearance
Off-white to yellow Solid
InChI
InChI=1S/C5H3ClN2O2/c6-4-1-3(5(9)10)7-2-8-4/h1-2H,(H,9,10)
InChIKey
RWSPRTBXAXZIOS-UHFFFAOYSA-N
SMILES
C1=NC(Cl)=CC(C(O)=O)=N1
More
Less

Safety

HS Code 
29335990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
B405203
Product name
6-Chloropyrimidine-4-carboxylicAcid
Packaging
500mg
Price
$130
Updated
2021/12/16
ChemScene
Product number
CS-W005983
Product name
6-Chloropyrimidine-4-carboxylicacid
Purity
≥98.0%
Packaging
1g
Price
$78
Updated
2021/12/16
Matrix Scientific
Product number
073471
Product name
6-Chloro-4-pyrimidinecarboxylic acid
Purity
95+%
Packaging
1g
Price
$120
Updated
2021/12/16
SynQuest Laboratories
Product number
4H58-5-4N
Product name
6-Chloropyrimidine-4-carboxylic acid
Purity
97.0%
Packaging
250mg
Price
$190
Updated
2021/12/16
ChemScene
Product number
CS-W005983
Product name
6-Chloropyrimidine-4-carboxylicacid
Purity
≥98.0%
Packaging
5g
Price
$228
Updated
2021/12/16
More
Less

6-Chloro-4-pyrimidinecarboxylic acid Chemical Properties,Usage,Production

Synthesis

6299-87-2

37131-91-2

General procedure for the synthesis of 6-chloropyrimidine-4-carboxylic acid from 6-hydroxy-4-pyrimidinecarboxylic acid: 2 g of 6-hydroxy-4-pyrimidinecarboxylic acid was dissolved in 30 mL of ethyl acetate, and oxalyl chloride (3.75 mL, 3 eq., 0.043 mol) was slowly added, followed by the addition of a few drops of N,N-dimethylformamide (gas was observed to escape). The reaction mixture was heated to reflux at 75 °C for 3 h, subsequently cooled to room temperature and allowed to stand overnight. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure to give a black solid product in quantitative yield. The resulting solid was to be stored under nitrogen protection at 4 °C.1H NMR analysis showed the product to be a mixture of 6-chloropyrimidine-4-carboxylic acid and its corresponding chloride derivatives (unstable at room temperature).1H NMR (d6-DMSO) data were as follows: 9.28 (s, 1H), 8.18 (s, 1H) for 6-chloropyrimidine-4-carboxylic acid; 8.45 (s, 1H), 8.45 (s, 1H), 8.93 (s, 1H), 8.45 (s, 1H), 8.45 (s, 1H), 8.45 (s, 1H), 6.93 (s, 1H) and 8.45 (s, 1H). 6.93 (s, 1H) for the signals of the chloride derivatives.

References

[1] Patent: WO2010/20432, 2010, A2. Location in patent: Page/Page column 91-92

6-Chloro-4-pyrimidinecarboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

6-Chloro-4-pyrimidinecarboxylic acid Suppliers

China 117 Germany 1 India 1 United Kingdom 1 United States 9 Global 129
langwaychem
Tel
21-67639201 13601755340
Email
customer@langwaychem.com
Country
China
ProdList
106
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16077
Advantage
64
Record Tech (Shanghai) Co., LTD
Tel
13761627472
Fax
86-21-64965863
Email
183009664@qq.com
Country
China
ProdList
649
Advantage
62
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
Advantage
60
Acorn PharmaTech Co., Ltd.
Tel
025-58395930
Fax
025-5861-9182
Email
sales@acornpharma.com
Country
China
ProdList
982
Advantage
60
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Hangzhou Sage Chemical Co., Ltd.
Tel
+86057186818502 13588463833
Fax
Pls mail us for more information!
Email
info@sagechem.com
Country
China
ProdList
10266
Advantage
58
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Qingdao Kingway Pharmtech Co., Ltd.
Tel
0532-87118899
Fax
0532-84117788
Email
sales@kingwaypharm.com
Country
China
ProdList
119
Advantage
56
BEIJING TDVINO TECHNOLOGY CO.,LTD
Tel
010-56371379
Fax
010-56371379
Country
China
ProdList
99
Advantage
55
Hubei XinyuanShun Chemical Co., Ltd.
Tel
13971561712, 13995564702, 027-50664929
Fax
027-50664927
Email
hbeixys2001@163.com
Country
China
ProdList
3120
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9476
Advantage
58
Mashilabs (Shanghai) Co.,Ltd.
Tel
19916721580
Fax
QQ：3154870176
Email
mafarm@126.com
Country
China
ProdList
4542
Advantage
58
ShangHai AmK Pharmaceutical Technology Co., Ltd.
Tel
微信 17321281695 18019252918
Fax
17321281695
Email
sale@amkchem.com
Country
China
ProdList
15136
Advantage
55
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9793
Advantage
50
Shanghai KaiYuLin pharmaceutical technology co., LTD
Tel
021-18721936-595 18721936595
Fax
-
Email
shkylpharma@126.com
Country
China
ProdList
736
Advantage
55
Shanghai YuanQi Biotechnology Co., Ltd.
Tel
+86-2332782371 +86-18120098618
Email
sales@adobechem.com
Country
China
ProdList
1250
Advantage
50
NovoChemy Ltd.
Tel
86-(0)21-31261262 373522135
Fax
86-(0)21-33250524
Email
sales@novochemy.com
Country
China
ProdList
6498
Advantage
58
SPIRO PHARMA
Tel
Fax
-
Email
eric_feng1954@126.com
Country
China
ProdList
9248
Advantage
55
Nanjing Chemcn Pharmaceutical Co., Ltd.
Tel
18114022054; 18114022054
Fax
+86-25-58857385
Email
3317707757@qq.com
Country
China
ProdList
301
Advantage
55
Nanjing YaoCheng Pharmaceutical Co., Ltd.
Tel
025-57043319 15261831516
Fax
025-57043319
Email
307514552@qq.com
Country
China
ProdList
251
Advantage
50
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Changzhou Hopschain Chemical Co.,Ltd.
Tel
0519-85528066 13775048983
Fax
0519-85528066
Email
sales@hopschem.com
Country
China
ProdList
31553
Advantage
55
Shanghai SuperLan Chemcial Technique Centre
Tel
0-2022843681 15618226720
Fax
+86-21-51601218
Email
chaolaichem@foxmail.com
Country
China
ProdList
10410
Advantage
58
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-55629727 13323845623
Fax
037155629727
Email
2885676761@qq.com
Country
China
ProdList
10109
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Beijing JingYun Biological Technology Co., Ltd.
Tel
15901553529
Fax
-
Email
3450343016@qq.com
Country
China
ProdList
48
Advantage
58
Adobe Chem Co., Ltd.
Tel
2332782371
Fax
QQ: 2332782371
Email
adobechem@qq.com
Country
China
ProdList
7980
Advantage
58
Chengdu Saiousi Pharmaceutical Co., Ltd
Tel
028-64971018 18108168130
Fax
86 028-64971018
Country
China
ProdList
1781
Advantage
55
Wuxi AppTec
Tel
022-59987777 13552403979
Email
jia_guoqiang@wuxiapptec.com
Country
China
ProdList
22345
Advantage
58
Capot Chemical Co.,Ltd.
Tel
+86-（0）57185586718; +8613336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29735
Advantage
60
Aikon International Limited
Tel
025-66061636 18013972705
Fax
(3)02557626880
Email
qqyang@aikonchem.com
Country
China
ProdList
15814
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.
Tel
027-51831887 15337167856
Fax
027-51837635 QQ1165326703
Email
hubeixinyuanshun@163.com
Country
China
ProdList
10295
Advantage
58
Shanghai SPAR pharmaceutical technology co., LTD
Tel
021-000000
Email
admin@jingshipharmatech.com
Country
China
ProdList
9857
Advantage
58
Shandong utilizing biological technology co., LTD
Tel
15966937598
Fax
3407640895 3071519937
Email
3407650895@qq.com
Country
China
ProdList
2274
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
Cool Pharm, Ltd
Tel
021-58581007 18019463053
Fax
021-50966098
Email
sales@coolpharm.com
Country
China
ProdList
5666
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2815688 13927872512
Fax
0751-8963795
Email
3007421951@qq.com
Country
China
ProdList
9939
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57422
Advantage
58
Nanjing Chengqian Pharmaceutical Technology Co., Ltd.
Tel
025-52791040 18652036685
Email
haozhongwen@126.com
Country
China
ProdList
767
Advantage
58
Suzhou Rovathin Foreign Trade Co.,Ltd
Tel
0512-65816829 18662214788
Fax
0512-65816829
Email
info@rovathin.com.cn
Country
China
ProdList
9987
Advantage
58
Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Country
China
ProdList
20284
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418671 +8618949823763
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34563
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
+86-0571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52846
Advantage
58
Baoji Guokang Healthchem Co., Ltd.
Tel
+86-0917-3909592 +86-13892490616
Fax
09173909592
Email
gksales1@gk-bio.com
Country
China
ProdList
9209
Advantage
58
KARMEL TECHNOLOGY (HK) CO.,LIMITED
Tel
+8618795957998
Email
karmelhk@126.com
Country
CHINA
ProdList
2886
Advantage
58
More
Less

View Lastest Price from 6-Chloro-4-pyrimidinecarboxylic acid manufacturers

Dideu Industries Group Limited
Product
6-Chloro-4-pyrimidinecarboxylic acid 37131-91-2
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons
Release date
2022-02-18
Zhuozhou Wenxi import and Export Co., Ltd
Product
6-Chloro-4-pyrimidinecarboxylic acid 37131-91-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
6-Chloro-4-pyrimidinecarboxylic acid 37131-91-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

37131-91-2, 6-Chloro-4-pyrimidinecarboxylic acidRelated Search:


  • 6-Chloro-4-pyrimidinecarboxylic acid
  • 6-chloropyrimidine-4-carboxylic acid
  • 4-PyriMidinecarboxylic acid, 6-chloro-
  • 6-Chloro-pyrimidin-4-carboxylic acid
  • 6-Chloropyrimidine-4-carboxylic acid 97%
  • 6-Chloro-4-pyrimidinecarboxylic acid ISO 9001：2015 REACH
  • 6-Chlor-pyrimidin-4-carbonsaeure
  • 4-Chloro-6-pyrimidinecarboxylic acid
  • 37131-91-2
  • pharmacetical
  • pyrimidine
  • Heterocycle-Pyrimidine series