Hexyl methanesulfonate
- Product Name
- Hexyl methanesulfonate
- CAS No.
- 16156-50-6
- Chemical Name
- Hexyl methanesulfonate
- Synonyms
- Hexyl mesylate;n-HexylMesylate;1-Hexylmesylate;n-Hexylmesylate, 98 %;hexyl metnanesulfonate;Hexyl Methanesulfonate;Cytarabine Impurity 59;Dabigatran Impurity 96;HexylMethanesulfonate>Dabigatran EP Impurity D
- CBNumber
- CB81509832
- Molecular Formula
- C7H16O3S
- Formula Weight
- 180.27
- MOL File
- 16156-50-6.mol
Hexyl methanesulfonate Property
- Boiling point:
- 90°C/2mmHg(lit.)
- Density
- 1.06
- refractive index
- 1.4320-1.4360
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly)
- form
- Oil
- color
- Colourless to Pale Yellow
- InChI
- InChI=1S/C7H16O3S/c1-3-4-5-6-7-10-11(2,8)9/h3-7H2,1-2H3
- InChIKey
- URIRDRHUUFRHAS-UHFFFAOYSA-N
- SMILES
- CS(OCCCCCC)(=O)=O
Safety
- HS Code
- 2904.10.5000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- H1282
- Product name
- Hexyl Methanesulfonate
- Purity
- >96.0%(GC)
- Packaging
- 5g
- Price
- $44
- Updated
- 2025/07/31
- Product number
- H1282
- Product name
- Hexyl Methanesulfonate
- Purity
- >96.0%(GC)
- Packaging
- 25g
- Price
- $134
- Updated
- 2025/07/31
- Product number
- H297155
- Product name
- Hexyl Methanesulfonate
- Packaging
- 5g
- Price
- $155
- Updated
- 2021/12/16
- Product number
- CHM0068812
- Product name
- HEXYL METHANESULFONATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $497.76
- Updated
- 2021/12/16
- Product number
- 8051AL
- Product name
- Hexyl Methanesulfonate
- Packaging
- 25g
- Price
- $544
- Updated
- 2021/12/16
Hexyl methanesulfonate Chemical Properties,Usage,Production
Uses
Hexyl Methanesulfonate is a methanesulfpnate agent and potential anticancer agent that is can easily cross the blood-brain barrier.
Synthesis
124-63-0
111-27-3
16156-50-6
Hexanol (50 mmol, 1 eq.) and triethylamine (11.08 mL, 80 mmol, 1.6 eq.) were dissolved in dichloromethane (60 mL), and the reaction system was cooled to 0 °C. Subsequently, methanesulfonyl chloride (4.33 mL, 56 mmol, 1.12 eq.) was slowly added dropwise via syringe. The reaction mixture was stirred at 0 °C for 30 min, then brought to room temperature and continued to stir overnight. After completion of the reaction, the organic layer was washed sequentially with 1 M hydrochloric acid solution, saturated aqueous sodium bicarbonate solution and brine. The organic layer was dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. Finally, hexyl methanesulfonate was purified by silica gel column chromatography (eluent ratio: ethyl acetate:petroleum ether=1:2).
References
[1] Organic and Biomolecular Chemistry, 2018, vol. 16, # 41, p. 7753 - 7759
[2] Journal of the American Chemical Society, 1985, vol. 107, # 18, p. 5210 - 5219
[3] Journal of Fluorine Chemistry, 2018, vol. 214, p. 35 - 41
[4] Journal of the Electrochemical Society, 2010, vol. 157, # 9, p. F124-F129
[5] European Journal of Organic Chemistry, 2018, vol. 2018, # 35, p. 4850 - 4856
Hexyl methanesulfonate Preparation Products And Raw materials
Raw materials
Preparation Products
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