ChemicalBook > CAS DataBase List > Ac-Arg-Leu-Arg-AMC

Ac-Arg-Leu-Arg-AMC

Product Name: Ac-Arg-Leu-Arg-AMC
CAS No.: 929903-87-7
Chemical Name: Ac-Arg-Leu-Arg-AMC
Synonyms: Ac-RLR-AMC;Ac-Arg-Leu-Arg-AMC;Ac-Arg-Leu-Arg-AMC trifluoroacetate salt;N2-Acetyl-L-arginyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-argininamide;L-Argininamide,N2-acetyl-L-arginyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
CBNumber: CB81513176
Molecular Formula: C30H46N10O6
Formula Weight: 642.75
MOL File: 929903-87-7.mol

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Ac-Arg-Leu-Arg-AMC Property

Density: 1.39±0.1 g/cm3(Predicted)
pka: 13.29±0.46(Predicted)
color: Solid lyophilized powder
Sequence: Ac-Arg-Leu-Arg-AMC

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological

Product number: 226820
Product name: Ac-Arg-Leu-Arg-AMC
Packaging: 1mg
Price: $295
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0020997
Product name: AC-ARG-LEU-ARG-AMC
Purity: 95.00%
Packaging: 5MG
Price: $530
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA110603
Product name: Ac-Arg-Leu-Arg-AMC trifluoroacetate salt
Packaging: 5mg
Price: $570
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA110603
Product name: Ac-Arg-Leu-Arg-AMC trifluoroacetate salt
Packaging: 10mg
Price: $991.3
Updated: 2021/12/16

Adipogen Life Sciences

Product number: AG-CP3-0013-M001
Product name: Ac-Arg-Leu-Arg-AMC
Purity: ≥97%(HPLC)
Packaging: 1mg
Price: $55
Updated: 2021/12/16

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Ac-Arg-Leu-Arg-AMC Chemical Properties,Usage,Production

Uses

Ac-RLR-AMC (Ac-Arg-Leu-Arg-AMC) is a fluorogenic substrate for the 26S proteasome (Ex/Em: 380/440-460 nm). AMC is released upon cleavage, and its fluorescence can be used to quantify the trypsin-like activity of 26S proteasomes[1].

Biological Activity

Fluorogenic tri-peptide substrate for measuring the trypsin-like peptidase activity of the 20S proteasome. It is cleaved exclusively at the amide R-AMC bond to release fluorescent product. Shows low Km and high specific activity. Excitation: 380nm. Emission: 460nm. This substrate is useful for inhibitor screening and kinetic analysis.

storage

+4°C

References

[1] Chang TL. Inhibitory effect of flavonoids on 26S proteasome activity. J Agric Food Chem. 2009 Oct 28;57(20):9706-15. DOI:10.1021/jf9017492

Ac-Arg-Leu-Arg-AMC Preparation Products And Raw materials

Raw materials

Preparation Products

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929903-87-7, Ac-Arg-Leu-Arg-AMCRelated Search:

Ac-Arg-Leu-Arg-AMC

Ac-RLR-AMC

Ac-Arg-Leu-Arg-AMC trifluoroacetate salt

N2-Acetyl-L-arginyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-argininamide

L-Argininamide,N2-acetyl-L-arginyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-

929903-87-7

C30H46N10O6