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B-NICOTYRINE

Product Name
B-NICOTYRINE
CAS No.
487-19-4
Chemical Name
B-NICOTYRINE
Synonyms
NICOTYRINE;Pyridine, 3-(1-methyl-1H-pyrrol-2-yl)-;β-Nicotyrine;BETA-NICOTYRINE;3-(1-METHYL-1H-PYRROL-2-YL)PYRIDINE;B-NICOTYRINE;3,2’-nicotyrine;BETA-NITROTYRINE;alpha-nicotyrine;Nicotine Impurity B
CBNumber
CB8154891
Molecular Formula
C10H10N2
Formula Weight
158.2
MOL File
487-19-4.mol
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B-NICOTYRINE Property

Melting point:
168-169 °C
Boiling point:
78-80°C/0/15mm
Density 
1.2410
refractive index 
1.6057 (estimate)
storage temp. 
-20°C Freezer, Under Inert Atmosphere
solubility 
Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly), Met
form 
Oil
pka
pK1:4.76(+1) (25°C)
color 
Pale Yellow to Brown to Dark Orange
Stability:
Light, Air Sensitive
EPA Substance Registry System
Pyridine, 3-(1-methyl-1H-pyrrol-2-yl)- (487-19-4)
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Safety

HS Code 
2939800000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
16333
Product name
β-Nicotyrine
Purity
≥98%
Packaging
1mg
Price
$48
Updated
2024/03/01
Cayman Chemical
Product number
16333
Product name
β-Nicotyrine
Purity
≥98%
Packaging
5mg
Price
$119
Updated
2024/03/01
Cayman Chemical
Product number
16333
Product name
β-Nicotyrine
Purity
≥98%
Packaging
10mg
Price
$213
Updated
2024/03/01
Cayman Chemical
Product number
16333
Product name
β-Nicotyrine
Purity
≥98%
Packaging
25mg
Price
$414
Updated
2024/03/01
TRC
Product number
N445000
Product name
β-Nicotyrine
Packaging
1mg
Price
$80
Updated
2021/12/16
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B-NICOTYRINE Chemical Properties,Usage,Production

Description

The occurrence of this alkaloid in the cigar type of tobacco has been reported by Wenusch and subsequently confirmed by Spath and Kesztler. It forms a colour_x0002_less oil when pure and yields crystalline salts and derivatives, e.g. the p1atinichloride, m.p. 158°C; picrate, m.p. 170-1 °c and the methiodide, m.p. 2l1-3°e. It may also be prepared from nicotine by oxidation with silver oxide, silver acetate or potassium ferricyanide. With Zn and HCI, the base is reduced to nicotine and 4:5-dihydronicotyrine, b.p. 244-6°C, yielding a dipicrate, m.p. l64°e. In the presence of prepared Pt02, the latter may be further reduced to dihydrometanicotine, the dipicrate of which has m.p. 161-2°C. Nicotyrine may be converted directly into nicotine in one operation by controlled hydrogenation in the presence on Pd-e

Chemical Properties

Clear Light Red-Brown Oil

Uses

Nicotryrine is an alkaloid derived from the dehydrogenation of nicotine and its analog, nornicotine. An alkaloid occurring in cigaret smoke.

Definition

ChEBI: Nicotyrine is a member of pyridines.

Synthesis Reference(s)

The Journal of Organic Chemistry, 54, p. 2476, 1989 DOI: 10.1021/jo00271a052

References

Cahours, Etard., Bull. Soc. Chim. Fr., 34, 449 (1880)
Pictet, Crepieux., Ber., 28, 1904 (1895)
Pictet, Crepieux., ibid, 33, 2355 (1900)
Wibaut, Oberhoff., Rec. trav. Chim., 47,935 (1928)
Wenusch., Biochem. Zeit., 275,361 (1935)
Spath, Kesztler., Ber., 70,2450 (1937)
Spath, Wibaut, Kesztler., ibid, 71, 100 (1938)

B-NICOTYRINE Preparation Products And Raw materials

Raw materials

Preparation Products

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B-NICOTYRINE Suppliers

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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86-10-82849933
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jkinfo@jkchemical.com
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China
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3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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86-21-50328109
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3bsc@sina.com
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China
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Beijing Ouhe Technology Co., Ltd
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010-82967028 13552068683
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+86-10-82967029
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China
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Chemsky(shanghai)International Co.,Ltd.
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021-50135380
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shchemsky@sina.com
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China
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BOC Sciences
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1-631-485-4226; 16314854226
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info@bocsci.com
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United States
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T&W GROUP
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021-61551611 13296011611
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+86 21-50676805
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contact@trustwe.com
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ChemStrong Scientific Co.,Ltd
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0755-0755-66853366 13670046396
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0755-28363542
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sales@chem-strong.com
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BOC Sciences
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16314854226
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United States
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Shanghai SuperLan Chemcial Technique Centre
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021-2022843681 15618226720
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+86-21-51601218
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chaolaichem@foxmail.com
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Amadis Chemical Company Limited
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571-89925085
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sales@amadischem.com
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487-19-4, B-NICOTYRINERelated Search:


  • 3-(1-methyl-2-pyrrolyl)pyridine
  • 3,2’-nicotyrine
  • alpha-nicotyrine
  • B-NICOTYRINE
  • BETA-NICOTYRINE
  • 3-(1-METHYL-1H-PYRROL-2-YL)PYRIDINE
  • (3-(1)-METHYLPYRROL-2-YL)-PYRIDINE
  • NICOTYRINE
  • 1-Methyl-2-(3-pyridinyl)-1H-pyrrole
  • BETA-NITROTYRINE
  • 1-methyl-2-(3-pyridyl)pyrrole
  • 3-(1-methyl-1h-pyrrol-2-yl)-pyridin
  • 3-(1-methyl-2-pyrrolyl)-pyridin
  • Nicotine EP Impurity B
  • Pyridine, 3-(1-methyl-1H-pyrrol-2-yl)-
  • β-Nicotyrine
  • Nicotine Related Compound B (20 mg)
  • Nicotine EP Impurity B/ Nicotine Related Compound B (Nicotyrine)
  • Nicotine USP Related Compound B
  • 3-(1-methyl-1H-pyrrol-2-yl)pyridine (β-nicotyrine)
  • β-Nicotyrine,Inhibitor,tobacco alkaloid,betaNicotyrine,beta Nicotyrine,inhibit,Microwave irradiation,Nicotiana tabacum,Dehydrogenation,Nicotine metabolite,Drug Metabolite
  • Nicotine Impurity B
  • Nicotine EP Impurity B (beta-Nicotyrine)
  • Cinnamyl Chloride Impurity 11
  • 487-19-4
  • pharmacetical
  • Nicotine Derivatives
  • Heterocycles
  • Mutagenesis Research Chemicals