3-Fluoro-5-trifluoromethyl-pyridine-2-carbonitrile

Product Name: 3-Fluoro-5-trifluoromethyl-pyridine-2-carbonitrile
CAS No.: 80194-71-4
Chemical Name: 3-Fluoro-5-trifluoromethyl-pyridine-2-carbonitrile
Synonyms: 3-Fluoro-5-(trifluoroMethyl)picolinonitrile;2-Cyano-3-fluoro-5-(trifluoromethyl)pyridine;3-Fluoro-5-trifluoromethyl-pyridine-2-carbonitrile;3-Fluoro-5-(trifluoromethyl)-2-pyridinecarbonitrile;2-Pyridinecarbonitrile, 3-fluoro-5-(trifluoromethyl)-
CBNumber: CB81558951
Molecular Formula: C7H2F4N2
Formula Weight: 190.1
MOL File: 80194-71-4.mol

More

Less

3-Fluoro-5-trifluoromethyl-pyridine-2-carbonitrile Property

Boiling point:: 90-94 °C(Press: 30 Torr)
Density: 1.46±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
pka: -5.17±0.20(Predicted)
Appearance: Colorless to light yellow Liquid

More

Less

Safety

HS Code: 2933399990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: F401555
Product name: 3-Fluoro-5-(trifluoromethyl)pyridine-2-carbonitrile
Packaging: 100mg
Price: $75
Updated: 2021/12/16

AK Scientific

Product number: 9938AE
Product name: 3-Fluoro-5-(trifluoromethyl)pyridine-2-carbonitrile
Packaging: 1g
Price: $84
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H37-3-54
Product name: 3-Fluoro-5-(trifluoromethyl)pyridine-2-carbonitrile
Purity: 97%
Packaging: 5G
Price: $84
Updated: 2021/12/16

Apolloscientific

Product number: PC200219
Product name: 3-Fluoro-5-(trifluoromethyl)pyridine-2-carbonitrile
Packaging: 1g
Price: $19
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H37-3-54
Product name: 3-Fluoro-5-(trifluoromethyl)pyridine-2-carbonitrile
Purity: 97%
Packaging: 1g
Price: $31
Updated: 2021/12/16

More

Less

3-Fluoro-5-trifluoromethyl-pyridine-2-carbonitrile Chemical Properties,Usage,Production

Synthesis

80194-70-3

80194-71-4

General procedure for the synthesis of 2-cyano-3-fluoro-5-trifluoromethylpyridine from 3-chloro-2-cyano-5-trifluoromethylpyridine: Cesium fluoride (9.6 g, 63 mmol) and potassium carbonate (250 mg, 1.8 mmol) were suspended in anhydrous DMSO (50 mL) under nitrogen protection, heated to 80 °C and then added 3-chloro-2-cyano-5-trifluoromethyl pyridine (8.7 g, 42 mmol). After 10 min of reaction, the mixture was heated to 95 °C and maintained for 20 min. After completion of the reaction, it was cooled to 55 °C and poured into ice water. It was extracted twice with hexane and then once with dichloromethane. The organic phases were combined and evaporated to give the solid product 2-cyano-3-fluoro-5-trifluoromethylpyridine (8 g, 100% yield). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 7.91 (1H, d, J=7.6 Hz), 8.84 (1H, s).

References

[1] Patent: WO2005/47279, 2005, A1. Location in patent: Page/Page column 56
[2] Patent: US33478, 1990, E1
[3] Patent: US4565568, 1986, A
[4] Patent: US4678509, 1987, A

3-Fluoro-5-trifluoromethyl-pyridine-2-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

3-Fluoro-5-trifluoromethyl-pyridine-2-carbonitrile Suppliers

China 74 India 2 United Kingdom 1 United States 8 Global 85

Shijiazhuang Sdyano Fine Chemical Co., Ltd.

Tel: 0311-89250318 031166536426
Fax: 4000311741
Email: master@sjzsdyn.com
Country: China
ProdList: 2850
Advantage: 65

Changzhou Huanling Chemical Co., Ltd.

Tel: 0519-89803565 13776850645
Fax: 0519-89803575
Email: info4@huanlingchem.com
Country: China
ProdList: 892
Advantage: 68

Nanjing Lynsci Chemical Co., Ltd

Tel: +86-025-83208253 +86-13851694729
Fax: 0086-25-83208253
Email: layefe@163.com
Country: China
ProdList: 231
Advantage: 62

Wuhan ariel chemical Co., LTD.

Tel: 18986259541 18986259541
Fax: 027-87840182
Email: sales@3stc.com
Country: China
ProdList: 3744
Advantage: 58

Tianjin Jinyuda Chemical Co., Ltd.

Tel: 022-58013646 13011382049
Fax: 022-23854368
Email: sales@jinyudachem.com
Country: China
ProdList: 1944
Advantage: 55

China Shenyang Tyschem CO. ,LTD

Tel: +86-024-83607930; 18640359690
Fax: 024-83607930
Email: sales@honghuchem.com
Country: China
ProdList: 256
Advantage: 58

Wuhan Kaymke Chemical Co., Ltd.,

Tel: 027-87342388 18086026008
Fax: 027-87342388
Email: sales@kaymke.com
Country: China
ProdList: 3620
Advantage: 55

Suzhou Sino Rare Chemical Co., Ltd.

Tel: 0512-62857507
Fax: +86-512-62857507
Email: sales@sinorarechem.com
Country: China
ProdList: 998
Advantage: 58

Cochemical Ltd.

Tel: 029-86115547 17791676824
Fax: 02151602123
Email: sales@cochemical.com
Country: China
ProdList: 3014
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-400-164-7117 18317119277
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 40000
Advantage: 60

More

Less

View Lastest Price from 3-Fluoro-5-trifluoromethyl-pyridine-2-carbonitrile manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 3-Fluoro-5-trifluoromethyl-pyridine-2-carbonitrile 80194-71-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-06-04

Career Henan Chemical Co

Product: 3-Fluoro-5-trifluoromethyl-pyridine-2-carbonitrile 80194-71-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 100kg
Release date: 2020-03-11

80194-71-4, 3-Fluoro-5-trifluoromethyl-pyridine-2-carbonitrileRelated Search:

3-Fluoro-5-trifluoromethyl-pyridine-2-carbonitrile

3-Fluoro-5-(trifluoroMethyl)picolinonitrile

2-Cyano-3-fluoro-5-(trifluoromethyl)pyridine

2-Pyridinecarbonitrile, 3-fluoro-5-(trifluoromethyl)-

3-Fluoro-5-(trifluoromethyl)-2-pyridinecarbonitrile

80194-71-4