ChemicalBook > CAS DataBase List > FGIN-1-27

FGIN-1-27

Product Name
FGIN-1-27
CAS No.
142720-24-9
Chemical Name
FGIN-1-27
Synonyms
FGIN-1-27;FGIN-1-27,98%;N,N-DIHEXYL-2-(4-FLUOROPHENYL)INDOLE-3-ACETAMIDE;N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide;1H-Indole-3-acetamide, 2-(4-fluorophenyl)-N,N-dihexyl-;FGIN-1-27N,N-Dihexyl-2-(4-fluorophenyl)indole-3-acetamide;2-(2-(4-Fluorophenyl)-1H-indol-3-yl)-N,N-dihexylacetamide;indoleacetamide,Inhibitor,inhibit,BBB,FGIN127,blood brain barrier,FGIN 1 27,FGIN 1-27,peripheral benzodiazepine receptor,convulsions,Isoniazid,PBR
CBNumber
CB8157605
Molecular Formula
C28H37FN2O
Formula Weight
436.6
MOL File
142720-24-9.mol
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FGIN-1-27 Property

Melting point:
96-97 °C
Boiling point:
608.3±55.0 °C(Predicted)
Density 
1.0538 (estimate)
storage temp. 
2-8°C
solubility 
methanol: 20 mg/mL
form 
White powder.
pka
16.45±0.30(Predicted)
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Safety

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29339980
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D8555
Product name
N,N-Dihexyl-2-(4-fluorophenyl)indole-3-acetamide
Packaging
5mg
Price
$61.1
Updated
2024/03/01
Sigma-Aldrich
Product number
D8555
Product name
N,N-Dihexyl-2-(4-fluorophenyl)indole-3-acetamide
Packaging
25mg
Price
$206
Updated
2024/03/01
Cayman Chemical
Product number
18461
Product name
FGIN-1-27
Purity
≥98%
Packaging
5mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
18461
Product name
FGIN-1-27
Purity
≥98%
Packaging
10mg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
18461
Product name
FGIN-1-27
Purity
≥98%
Packaging
25mg
Price
$108
Updated
2024/03/01
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FGIN-1-27 Chemical Properties,Usage,Production

Chemical Properties

white to off-white powder

Uses

FGIN-1-27 is a potent inositol monophosphatase inhibitor.

Definition

ChEBI: 2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide is a phenylindole.

Biological Activity

Binds specifically and with high affinity to the peptide DBI receptor (benzodiazepine receptor) on mitochondrial membranes, inducing production of neurosteroids, which modulate GABA receptors (EC 50 = 3 nM for increase in production of pregnenolone in glial cells). Thus it reduces anxiety without causing sedation.

storage

Room temperature

FGIN-1-27 Preparation Products And Raw materials

Raw materials

Preparation Products

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FGIN-1-27 Suppliers

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142720-24-9, FGIN-1-27Related Search:


  • FGIN-1-27
  • N,N-DIHEXYL-2-(4-FLUOROPHENYL)INDOLE-3-ACETAMIDE
  • N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide
  • FGIN-1-27,98%
  • FGIN-1-27N,N-Dihexyl-2-(4-fluorophenyl)indole-3-acetamide
  • 1H-Indole-3-acetamide, 2-(4-fluorophenyl)-N,N-dihexyl-
  • indoleacetamide,Inhibitor,inhibit,BBB,FGIN127,blood brain barrier,FGIN 1 27,FGIN 1-27,peripheral benzodiazepine receptor,convulsions,Isoniazid,PBR
  • 2-(2-(4-Fluorophenyl)-1H-indol-3-yl)-N,N-dihexylacetamide
  • 142720-24-9
  • C28H37FN2O
  • Miscellaneous Enzyme