ChemicalBook > CAS DataBase List > (+/-)-15-HYDROXY-11Z,13E-EICOSADIENOIC ACID

(+/-)-15-HYDROXY-11Z,13E-EICOSADIENOIC ACID

Product Name
(+/-)-15-HYDROXY-11Z,13E-EICOSADIENOIC ACID
CAS No.
77159-57-0
Chemical Name
(+/-)-15-HYDROXY-11Z,13E-EICOSADIENOIC ACID
Synonyms
(+/-)15-HEDE;ZTRWPEHMGCHTIT-QWAPPMFBSA-N;(+/-)-15-HYDROXY-11Z,13E-EICOSADIENOIC ACID;11,13-Eicosadienoic acid, 15-hydroxy-, (11Z,13E)-
CBNumber
CB8160902
Molecular Formula
C20H36O3
Formula Weight
324.5
MOL File
77159-57-0.mol
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(+/-)-15-HYDROXY-11Z,13E-EICOSADIENOIC ACID Property

storage temp. 
Store at -20°C
solubility 
DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
37700
Product name
(±)15-HEDE
Purity
≥98%
Packaging
25μg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
37700
Product name
(±)15-HEDE
Purity
≥98%
Packaging
50μg
Price
$84
Updated
2024/03/01
Cayman Chemical
Product number
37700
Product name
(±)15-HEDE
Purity
≥98%
Packaging
100μg
Price
$155
Updated
2024/03/01
Cayman Chemical
Product number
37700
Product name
(±)15-HEDE
Purity
≥98%
Packaging
250μg
Price
$363
Updated
2024/03/01
AHH
Product number
MT-15003
Product name
(+/-)-15-Hydroxy-11Z,13E-eicosadienoic acid
Purity
98%
Packaging
0.001g
Price
$920
Updated
2021/12/16
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(+/-)-15-HYDROXY-11Z,13E-EICOSADIENOIC ACID Chemical Properties,Usage,Production

Uses

(±)15-HEDE is a racemic mixture of the monohydroxy fatty acids 15(R)-HEDE and 15(S)-HEDE. 15-HEDE is formed from eicosadienoic acid in macrophages. It inhibits 5-lipoxygenase (5-LO; IC50=35 μM).

Definition

ChEBI: 15-HEDE is a hydroxyeicosadienoic acid that consists of 11Z,13E-eicosatrienoic acid bearing a 15-hydroxy substituent. It is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid. There are no reports in the literature of biological activity associated with 15-HEDE. It has a role as a metabolite.

References

[1] Haviv, et al. Structural requirements for the inhibition of 5-lipoxygenase by 15-hydroxyeicosa-5,8,11,13-tetraenoic acid analogues. J. Med. Chem. 30(2), 254-263 (1987).

(+/-)-15-HYDROXY-11Z,13E-EICOSADIENOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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(+/-)-15-HYDROXY-11Z,13E-EICOSADIENOIC ACID Suppliers

Alfa Chemistry
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1-516-6625404
Fax
1-516-927-0118
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support@alfa-chemistry.com
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United States
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TargetMol Chemicals Inc.
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+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
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United States
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32435
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Cayman Chemical Company
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Email
cayman@caymanchem.com
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United States
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3B Scientific Corporation
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Email
sales@3bsc.com
Country
United States
ProdList
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77159-57-0, (+/-)-15-HYDROXY-11Z,13E-EICOSADIENOIC ACIDRelated Search:


  • (+/-)15-HEDE
  • (+/-)-15-HYDROXY-11Z,13E-EICOSADIENOIC ACID
  • ZTRWPEHMGCHTIT-QWAPPMFBSA-N
  • 11,13-Eicosadienoic acid, 15-hydroxy-, (11Z,13E)-
  • 77159-57-0
  • C20H36O3