ChemicalBook > CAS DataBase List > 1,4-DIBROMO-2,5-BIS(BROMMETHYL)BENZENE
1,4-DIBROMO-2,5-BIS(BROMMETHYL)BENZENE
Uses- Product Name
- 1,4-DIBROMO-2,5-BIS(BROMMETHYL)BENZENE
- CAS No.
- 35335-16-1
- Chemical Name
- 1,4-DIBROMO-2,5-BIS(BROMMETHYL)BENZENE
- Synonyms
- 1,4-Dibromo-2,5-bis(bromomethyl)benzene;1,4-Dibromo-2,5-bis(bromomethyl)benzene 97%;alpha,alpha,2,5-Tetrabromo-p-xylene;1,4-DIBROMO-2,5-BIS(BROMMETHYL)BENZENE;2,5-Bis(Bromomethyl)-1,4-dibromobenzene;1,4-bis(bromomethyl)-2,5-dibromobenzene;4-(Bromomethyl)-2,5-dibromobenzyl bromide;1,4-Bis(bromomethyl)-2,5-dibromobenzene97%;Benzene, 1,4-dibromo-2,5-bis(bromomethyl)-;1,4-Dibromo-2,5-bis(bromomethyl)benzene>
- CBNumber
- CB8162229
- Molecular Formula
- C8H6Br4
- Formula Weight
- 421.75
- MOL File
- 35335-16-1.mol
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1,4-DIBROMO-2,5-BIS(BROMMETHYL)BENZENE Property
- Melting point:
- 171-177℃
- Boiling point:
- 392℃
- Density
- 2.332
- Flash point:
- 185℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- powder to crystal
- color
- White to Light yellow
- Sensitive
- Lachrymatory
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Safety
- Hazard Codes
- C
- RIDADR
- 3261
- Hazard Note
- Corrosive/Lachrymatory
- HS Code
- 2903998090
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H290May be corrosive to metals
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P234Keep only in original container.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P390Absorb spillage to prevent material damage.
P405Store locked up.
P406Store in corrosive resistant/… container with a resistant inner liner.
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
TCI Chemical
- Product number
- D3961
- Product name
- 1,4-Dibromo-2,5-bis(bromomethyl)benzene
- Packaging
- 1G
- Price
- $92
- Updated
- 2025/07/31
TCI Chemical
- Product number
- D3961
- Product name
- 1,4-Dibromo-2,5-bis(bromomethyl)benzene
- Packaging
- 5G
- Price
- $299
- Updated
- 2025/07/31
TRC
- Product number
- D425118
- Product name
- 1,4-Dibromo-2,5-bis(bromomethyl)benzene
- Packaging
- 250mg
- Price
- $60
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- HCH0015715
- Product name
- 1,4-DIBROMO-2,5-BIS(BROMOMETHYL)BENZENE
- Purity
- 95.00%
- Packaging
- 500MG
- Price
- $728.85
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- HCH0015715
- Product name
- 1,4-DIBROMO-2,5-BIS(BROMOMETHYL)BENZENE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $821.99
- Updated
- 2021/12/16
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1,4-DIBROMO-2,5-BIS(BROMMETHYL)BENZENE Chemical Properties,Usage,Production
Uses
1,4-Dibromo-2,5-bis(bromomethyl)benzene is used as an organic and pharmaceutical intermediate.
Synthesis
1074-24-4
35335-16-1
General procedure for the synthesis of 1,4-dibromo-2,5-bis(bromomethyl)benzene from 2,5-dibromo-1,4-dimethylbenzene: 2,5-dibromo-p-xylene (26.4 g, 0.1 mol) and N-bromosuccinimide (NBS, 39 g, 0.22 mol) were suspended in carbon tetrachloride (300 mL), and benzoyl peroxide (0.6 g) was added as the initiator. Prior to the start of the reaction, a nitrogen stream was passed through the bubble for 5 min to exclude oxygen. Subsequently, the reaction mixture was heated and refluxed in an oil bath at 100 °C for 2 hours. Upon completion of the reaction, ethanol (200 mL) was added to precipitate the product and the solid was collected by filtration. The solid was washed with ethanol (50 mL) to remove residual reactants and by-products and finally dried under vacuum to afford 1,4-dibromo-2,5-bis(bromomethyl)benzene as a white solid (13.36 g, 31.6% yield). The structure of the product was confirmed by 1H-NMR (500 MHz, CDCl3): δ 7.68 (s, 2H, aryl ring hydrogen), 4.50 (s, 4H, bromomethyl hydrogen).
References
[1] Tetrahedron Letters, 2007, vol. 48, # 35, p. 6075 - 6079
[2] Organic and Biomolecular Chemistry, 2010, vol. 8, # 24, p. 5620 - 5627
[3] Journal of the American Chemical Society, 2017, vol. 139, # 45, p. 16210 - 16221
[4] Journal of the American Chemical Society, 2017, vol. 139, # 47, p. 17082 - 17088
[5] Journal of the American Chemical Society, 2009, vol. 131, # 49, p. 17724 - 17725
1,4-DIBROMO-2,5-BIS(BROMMETHYL)BENZENE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1,4-DIBROMO-2,5-BIS(BROMMETHYL)BENZENE manufacturers
Shaanxi Dideu Medichem Co. Ltd
- Product
- 1,4-DIBROMO-2,5-BIS(BROMMETHYL)BENZENE 35335-16-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-08-16
Career Henan Chemical Co
- Product
- 1,4-DIBROMO-2,5-BIS(BROMMETHYL)BENZENE 35335-16-1
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2020-01-14