2-METHYL-2-(1-METHYLPROPYL)-1,3-PROPANEDIOL DICARBAMATE

Product Name: 2-METHYL-2-(1-METHYLPROPYL)-1,3-PROPANEDIOL DICARBAMATE
CAS No.: 64-55-1
Chemical Name: 2-METHYL-2-(1-METHYLPROPYL)-1,3-PROPANEDIOL DICARBAMATE
Synonyms: Capla;Prean;W 583;Axiten;Dormate;Encapla;Vallene;Carbuten;Mebutina;No-Press
CBNumber: CB8164021
Molecular Formula: C10H20N2O4
Formula Weight: 232.28
MOL File: 64-55-1.mol

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2-METHYL-2-(1-METHYLPROPYL)-1,3-PROPANEDIOL DICARBAMATE Property

Melting point:: 77-79°
Boiling point:: 374.44°C (rough estimate)
Density: 1.1633 (rough estimate)
refractive index: 1.4710 (estimate)

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Safety

Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
Toxicity: LD50 oral in rat: 1160mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: CHM0009057
Product name: 2-METHYL-2-(1-METHYLPROPYL)-1,3-PROPANEDIOL DICARBAMATE
Purity: 95.00%
Packaging: 5MG
Price: $496.38
Updated: 2021/12/16

AHH

Product number: MT-18190
Product name: 2-Methyl-2-(1-methylpropyl)-1,3-propanedioldicarbamate
Purity: 98%
Packaging: 50g
Price: $510
Updated: 2021/12/16

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2-METHYL-2-(1-METHYLPROPYL)-1,3-PROPANEDIOL DICARBAMATE Chemical Properties,Usage,Production

Originator

Capla,Wallace,US,1961

Uses

Antihypertensive.

Definition

ChEBI: Mebutamate is an organic molecular entity.

Manufacturing Process

The following example illustrates the preparation of 2-methyl-2-sec-butyl-1,3- propanediol:
92 g of diethyl-sec-butyl methyl malonate were reduced in the usual manner using 22.8 g of lithium aluminum hydride in a suitable volume of anhydrous ethyl ether. The mixture was treated with 10% sulfuric acid and the ether soluble components extracted. The ether solution was dried, using a suitable drying agent, and the residue obtained by the removal of the ether was purified by distilling under reduced pressure. This material was further purified by redistillation. Approximately 46 g of 2-methyl-2-sec-butyl-1,3-propanediol were obtained as a clear colorless liquid, boiling point 92°C to 97°C (0.1 mm pressure).
The following example describes the preparation of 2-methyl-2-sec-butyl-1,3- propanediol dicarbamate using the urethane exchange method:
14.6 g of 2-methyl-2-sec-butyl-1,3-propanediol and 18.7 g ethyl urethane are dissolved in about 100 ml anhydrous toluene. 3 g of aluminum isopropylate are added and the mixture distilled to remove the ethyl alcohol formed in the condensation of ethyl urethane and the diol. The alcohol distills in the form of an azeotrope with toluene. Distillation is continued until the theoretical quantity of ethanol has been removed. The toluene is distilled from the mixture under reduced pressure and the residue dissolved in hot aqueous isopropanol solution. The hot solution is filtered and allowed to cool, whereupon approximately 14 g of product separates. The purified product represents a yield of about 60% of theoretical and melts at 77°C to 79°C.

brand name

Dormate (Medpointe).

Therapeutic Function

Antihypertensive

2-METHYL-2-(1-METHYLPROPYL)-1,3-PROPANEDIOL DICARBAMATE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-METHYL-2-(1-METHYLPROPYL)-1,3-PROPANEDIOL DICARBAMATE Suppliers

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64-55-1, 2-METHYL-2-(1-METHYLPROPYL)-1,3-PROPANEDIOL DICARBAMATERelated Search:

Olmesartan Medoxomil Propylene glycol 1,3-Propanediol 2-(1-Ethylpropyl)-2-methyl-1,3-propanediol dicarbamate 2-Methyl-2-propyl-1,3-propanediol 2-METHYL-2-(1-METHYLPROPYL)-1,3-PROPANEDIOL DICARBAMATE n-Butyl carbamate Meprobamate Carbamic acid, 2,2-dimethylbutyl ester Nisobamate N-PROPYLCARBAMATE

1,3-Propanediol, 2-methyl-2-(1-methylpropyl)-, dicarbamate

1,3-Propanediol, 2-sec-butyl-2-methyl-, dicarbamate

2,2-Dicarbamyloxymethyl-3-methylpentane

2-Methyl-2-sec-butyl-1,3-propanediol dicarbamate

2-methyl-2-sec-butyl-1,3-propanedioldicarbamate

2-sec-Butyl-2-methyl-1,3-propanediol dicarbamate

2-sec-butyl-2-methyl-1,3-propanedioldicarbamate

2-sec-Butyl-2-methyltrimethylene dicarbamate

2-sec-butyl-2-methyltrimethylenedicarbamate

2-sec-butyl-carbamicaci2-methyltrimethyleneester

3-propanediol,2-sec-butyl-2-methyl-dicarbamate

Axiten

Butatensin

Capla

Carbamic acid, 2-sec-butyl-2-methyltrimethylene ester

Carbuten

Dicamoylmethane

Dicamoylmethtane

Dormate

Encapla

Ipotensivo

Mebutamat

Mebutina

No-Press

Prean

Preminex

Sigmafon

Vallene

W 583

2-Methyl-2-(1-methylpropyl)-1,3-propandioldicarbamate

Bis(carbamic acid)2-(1-methylpropyl)-2-methyl-1,3-propanediyl ester

MEBUTAMATE

2-METHYL-2-(1-METHYLPROPYL)-1,3-PROPANEDIOL DICARBAMATE

[2-(aminocarbonyloxymethyl)-2,3-dimethyl-pentyl] carbamate

[2-(carbamoyloxymethyl)-2,3-dimethylpentyl] carbamate

carbamic acid [2-(carbamoyloxymethyl)-2,3-dimethyl-pentyl] ester

2-Methyl-2-(1-methylpropyl)-1,3-propanediolDicarbamate&gt

1,3-Propanediol, 2-methyl-2-(1-methylpropyl)-, 1,3-dicarbamate

64-55-1