ChemicalBook > CAS DataBase List > 17-OCTADECYNOIC ACID

17-OCTADECYNOIC ACID

Product Name
17-OCTADECYNOIC ACID
CAS No.
34450-18-5
Chemical Name
17-OCTADECYNOIC ACID
Synonyms
ODYA;17-ODA;P450scc;17-ODYA;Alkyne-stearic acid;17-OCTADECYNOIC ACID;Alkynyl Stearic Acid;Octadec-17-ynoic acid;17-ODYA, 10 mM in DMSO;DZIILFGADWDKMF-UHFFFAOYSA-N
CBNumber
CB8175243
Molecular Formula
C18H32O2
Formula Weight
280.45
MOL File
34450-18-5.mol
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17-OCTADECYNOIC ACID Property

Boiling point:
400.8±18.0 °C(Predicted)
Density 
0.922±0.06 g/cm3(Predicted)
storage temp. 
Store at RT
solubility 
Soluble to 50 mM in ethanol and to 100 mM in DMSO
form 
White solid.
pka
4.78±0.10(Predicted)
color 
White to off-white
CAS DataBase Reference
34450-18-5(CAS DataBase Reference)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
O8382
Product name
17-Octadecynoic acid
Purity
≥95% (GC)
Packaging
5mg
Price
$304
Updated
2024/03/01
Sigma-Aldrich
Product number
O8382
Product name
17-Octadecynoic acid
Purity
≥95% (GC)
Packaging
25mg
Price
$1160
Updated
2024/03/01
Cayman Chemical
Product number
90270
Product name
17-Octadecynoic Acid
Purity
≥98%
Packaging
1mg
Price
$16
Updated
2024/03/01
Cayman Chemical
Product number
90270
Product name
17-Octadecynoic Acid
Purity
≥98%
Packaging
5mg
Price
$63
Updated
2024/03/01
Cayman Chemical
Product number
90270
Product name
17-Octadecynoic Acid
Purity
≥98%
Packaging
10mg
Price
$109
Updated
2024/03/01
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17-OCTADECYNOIC ACID Chemical Properties,Usage,Production

Description

Alkynyl stearic acid can be used to identify and characterize the post-translational acylation of proteins with powerful Click Chemistry.

Uses

17-ODYA (17-Octadecynoic acid) is a potent suicide inhibitor of LTB4 ω-oxidase.

Definition

ChEBI: Octadec-17-ynoic acid is an acetylenic fatty acid that is octadecanoi acid (stearic acid) which has been doubly dehydrogenated at positions 17 and 18 to give the corresponding alkynoic acid. It has a role as a P450 inhibitor, an EC 1.14.14.94 (leukotriene-B4 20-monooxygenase) inhibitor and an EC 1.14.15.3 (alkane 1-monooxygenase) inhibitor. It is a long-chain fatty acid, an acetylenic fatty acid, a terminal acetylenic compound and a monounsaturated fatty acid.

Biological Activity

Potent suicide inhibitor of LTB 4 ω -hydroxylase.

Biochem/physiol Actions

17-Octadecynoic acid (7-ODYA) is an irreversible inhibitor of cytochrome P450 isozymes, that participates in long-chain fatty acid metabolism.

storage

Store at -20°C

17-OCTADECYNOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 17-OCTADECYNOIC ACID manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Alkynyl Stearic Acid 34450-18-5
Price
US $0.00/mg
Min. Order
5mg
Purity
>95.00%
Supply Ability
5mg
Release date
2024-03-21
Career Henan Chemical Co
Product
17-OCTADECYNOIC ACID 34450-18-5
Price
US $1.00/KG
Min. Order
1KG
Purity
85.0-99.8%
Supply Ability
20 tons
Release date
2019-12-24

34450-18-5, 17-OCTADECYNOIC ACIDRelated Search:


  • 17-ODA
  • 17-ODYA
  • 17-OCTADECYNOIC ACID
  • ODYA
  • 17-OCTADECYNOIC ACID \ CYTOCHROME P450 E
  • 17-ODYA (17-Octadecynoic acid)
  • Alkynyl Stearic Acid
  • DZIILFGADWDKMF-UHFFFAOYSA-N
  • acids,cardiomyocytes,Inhibitor,inhibit,17-ODYA,20-HETE,reperfusion,epoxyeicosatrienoic,CYPs,dihydroxyeicosatrienoic,ischemia,17ODYA,Cytochrome P450,17 ODYA
  • P450scc
  • Alkyne-stearic acid
  • Octadec-17-ynoic acid
  • 17-ODYA, 10 mM in DMSO
  • 34450-18-5
  • Enzymes, Inhibitors, and Substrates
  • Enzyme Inhibitors by Enzyme
  • Enzyme Inhibitors
  • Cytochrome P450
  • BioChemical
  • Biochemicals and Reagents
  • A to C
  • Cytochrome P450Enzyme Inhibitors by Enzyme
  • Cytochrome P450Unsaturated fatty acids and derivatives
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  • Arachidonic Acid Cascade
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