N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-SPHINGANINE

Product Name
N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-SPHINGANINE
CAS No.
474943-05-0
Chemical Name
N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-SPHINGANINE
Synonyms
C12 NBD SAFINGOL;NBD-C12-SAFINGOL;C12 NBD SPHINGANINE;N-(NBD-AMINOLAUROYL)SAFINGOL;N-ACYL-SPHINGANINE (C12 NBD);N-(NBD-AMINOLAUROYL)SPHINGANINE;C12 NBD dihydro Ceramide (d18:0/12:0);N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-SPHINGANINE;N-[6-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-L-THREO-SPHINGANINE;N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-L-THREO-SPHINGANINE
CBNumber
CB8179463
Molecular Formula
C36H63N5O6
Formula Weight
661.92
MOL File
Mol file
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N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-SPHINGANINE Property

Density 
1.095±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml
form 
A solid
pka
14.30±0.20(Predicted)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-38-40-48/20/22
Safety Statements 
36/37
RIDADR 
UN 1888 6.1/PG 3
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10008097
Product name
C12 NBD dihydro Ceramide (d18:0/12:0)
Purity
≥98%
Packaging
1mg
Price
$178
Updated
2024/03/01
Cayman Chemical
Product number
10008097
Product name
C12 NBD dihydro Ceramide (d18:0/12:0)
Purity
≥98%
Packaging
5mg
Price
$793
Updated
2024/03/01
Cayman Chemical
Product number
10008097
Product name
C12 NBD dihydro Ceramide (d18:0/12:0)
Purity
≥98%
Packaging
10mg
Price
$1407
Updated
2024/03/01
TRC
Product number
N381268
Product name
C-12NBD-dihydro-Ceramide
Packaging
1mg
Price
$290
Updated
2021/12/16
TRC
Product number
N381268
Product name
C-12NBD-dihydro-Ceramide
Packaging
2.5mg
Price
$585
Updated
2021/12/16
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N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-SPHINGANINE Chemical Properties,Usage,Production

Uses

C-12 NBD-dihydro-Ceramide is a fluorescent ceramidase substrate. C-12 NBD-dihydro-Ceramide compound is a fluorescent ceramide analog which contains a saturated bond in the C4-C5 position of the sphingosine backbone. It can be used for the measurement of alkaline and neutral ceramidase activity from a variety of sources. C-12 NBD-dihydro-ceramide may exhibit reduced activity in ceramidase assays compared to C-12 NBD ceramide. This is based on the observation that saturation of the C4-C5 sphingosine bond in C16-ceramide results in approximately a 10-fold reduction in efficiency as a substrate for rat brain ceramidase compared to the unsaturated substrate. Yet, experimental characterization of C-12 NBD-dihydro-ceramide as a ceramidase substrate needs to be performed.

N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-SPHINGANINE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-SPHINGANINE Suppliers

SIGMA-RBI
Tel
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Fax
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Country
Switzerland
ProdList
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Advantage
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474943-05-0, N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-SPHINGANINERelated Search:


  • NBD-C12-SAFINGOL
  • N-ACYL-SPHINGANINE (C12 NBD)
  • N-(NBD-AMINOLAUROYL)SAFINGOL
  • N-(NBD-AMINOLAUROYL)SPHINGANINE
  • N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-SPHINGANINE
  • N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-L-THREO-SPHINGANINE
  • N-[6-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-L-THREO-SPHINGANINE
  • C12 NBD dihydro Ceramide (d18:0/12:0)
  • N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-SPHINGANINE;C12-NBD SPHINGANINE
  • C12 NBD SAFINGOL
  • C12 NBD SPHINGANINE
  • C12-NBD Sphinganine, N-[12-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-sphinganine
  • NBD-C12-Safingol, N-[6-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-L-threo-sphinganine
  • Dodecanamide, N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl]-12-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-
  • 474943-05-0
  • C36H63N5O6
  • Lipids
  • Other Lipid Related Products
  • Sphingolipids
  • BioChemical
  • Biochemicals and Reagents
  • Ceramides
  • Fluorescent labeled lipids for membrane probes