9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID

Product Name: 9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID
CAS No.: 74034-56-3
Chemical Name: 9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID
Synonyms: CTA2;Carbocyclic TxA2;CARBOCYCLIC THROMBOXANE A2;(+/-)CARBOCYCLIC THROMBOXANE;(Z)-7-[(2S)-3β-[(1E,3S)-3-Hydroxy-1-octenyl]bicyclo[3.1.1]heptan-2α-yl]-5-heptenoic acid;9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID;5-Heptenoic acid, 7-[(2S,3R)-3-[(1E,3S)-3-hydroxy-1-octen-1-yl]bicyclo[3.1.1]hept-2-yl]-, (5Z)-
CBNumber: CB8182957
Molecular Formula: C22H36O3
Formula Weight: 348.52
MOL File: 74034-56-3.mol

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9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID Property

storage temp.: Store at -20°C
solubility: DMF: 50 mg/ml; DMSO: 25 mg/ml; Ethanol: 100 mg/ml; PBS pH 7.2: 100 μg/ml

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 19010
Product name: Carbocyclic Thromboxane A2
Purity: ≥98%
Packaging: 100μg
Price: $52
Updated: 2023/06/20

Cayman Chemical

Product number: 19010
Product name: Carbocyclic Thromboxane A2
Purity: ≥98%
Packaging: 500μg
Price: $238
Updated: 2023/06/20

Cayman Chemical

Product number: 19010
Product name: Carbocyclic Thromboxane A2
Purity: ≥98%
Packaging: 1mg
Price: $450
Updated: 2023/06/20

Cayman Chemical

Product number: 19010
Product name: Carbocyclic Thromboxane A2
Purity: ≥98%
Packaging: 5mg
Price: $945
Updated: 2021/12/16

TRC

Product number: C178783
Product name: CarbocyclicThromboxaneA2
Packaging: 250μg
Price: $95
Updated: 2021/12/16

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9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID Chemical Properties,Usage,Production

Description

Carbocyclic thromboxane A₂ (CTA₂) is a stable analog of TXA₂. CTA₂ is a potent coronary vasoconstrictor and is effective at concentrations as low as 1 nM in cat coronary arteries. Unlike other vascular TP receptor agonists, CTA₂ is a potent inhibitor of prostanoid-induced platelet aggregation. It inhibits arachidonic acid-induced aggregation with an IC₅₀ value of 4-5 μM. CTA₂ also exhibits selective and dose-dependent inhibition of TXB₂ synthesis in rabbit platelets at concentrations between 1 and 100 μM.

Uses

Carbocyclic Thromboxane A2 is a stable analog of TXA2 which inhibits thromboxane-mediated vasoconstriction platelet aggregation. Also, it converts the thromboxane synthase (TXAS) heme cofactor to its 5-coordinate.

9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID Suppliers

China 11 Germany 1 India 1 United Kingdom 1 United States 4 Global 18

Cayman Chemical Company

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Country: United States
ProdList: 6213
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United States Biological

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3B Scientific Corporation

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MP Biomedicals, Inc.

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ProdList: 6561
Advantage: 81

74034-56-3, 9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACIDRelated Search:

5-CAPROLEIC ACID CIS-5-DODECENOIC ACID 9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID ISO-PROPYLCYCLOBUTANE 2-(3-ALLYL)-4-PENTEN-1-OL TRIMETHYLENE OXIDE

9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID

(+/-)CARBOCYCLIC THROMBOXANE

(Z)-7-[(2S)-3β-[(1E,3S)-3-Hydroxy-1-octenyl]bicyclo[3.1.1]heptan-2α-yl]-5-heptenoic acid

Carbocyclic TxA2

CTA2

CARBOCYCLIC THROMBOXANE A2

5-Heptenoic acid, 7-[(2S,3R)-3-[(1E,3S)-3-hydroxy-1-octen-1-yl]bicyclo[3.1.1]hept-2-yl]-, (5Z)-

74034-56-3