ChemicalBook > CAS DataBase List > 2-(Pyridin-3-yl)propan-2-ol

2-(Pyridin-3-yl)propan-2-ol

Product Name
2-(Pyridin-3-yl)propan-2-ol
CAS No.
15031-77-3
Chemical Name
2-(Pyridin-3-yl)propan-2-ol
Synonyms
2-(3-Pyridyl)-2-propanol;2-(Pyridin-3-yl)propan-2-ol;3-(2-Hydroxyprop-2-yl)pyridine;3-Pyridinemethanol, α,α-dimethyl-;3-(1-hydroxy-1-methylethyl)pyridine
CBNumber
CB81870493
Molecular Formula
C8H11NO
Formula Weight
137.18
MOL File
15031-77-3.mol
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2-(Pyridin-3-yl)propan-2-ol Property

Melting point:
53 °C
Boiling point:
130 °C(Press: 11 Torr)
Density 
1.052±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
pka
13.82±0.29(Predicted)
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H320Causes eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
P840980
Product name
2-(Pyridin-3-yl)propan-2-ol
Packaging
100mg
Price
$155
Updated
2021/12/16
AK Scientific
Product number
Y7594
Product name
2-(Pyridin-3-yl)propan-2-ol
Packaging
250mg
Price
$222
Updated
2021/12/16
Ambeed
Product number
A516487
Product name
2-(Pyridin-3-yl)propan-2-ol
Purity
97%
Packaging
100mg
Price
$89
Updated
2021/12/16
Ambeed
Product number
A516487
Product name
2-(Pyridin-3-yl)propan-2-ol
Purity
97%
Packaging
250mg
Price
$120
Updated
2021/12/16
AstaTech
Product number
50806
Product name
2-(PYRIDIN-3-YL)PROPAN-2-OL
Purity
97%
Packaging
0.25/ G
Price
$158
Updated
2021/12/16
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2-(Pyridin-3-yl)propan-2-ol Chemical Properties,Usage,Production

Synthesis

350-03-8

15031-77-3

The general procedure for synthesizing 2-(pyridin-3-yl)propan-2-ol from 3-acetylpyridine was as follows: an ether solution of methyl lithium (1.4 M, 14 mL, 20 mmol) was used to react with 3-acetylpyridine (2.2 mL, 20 mmol) in dry tetrahydrofuran (40 mL) according to the method of Example 4a. After completion of the reaction, the product was purified by post-treatment and column chromatography using ether- petroleum ether-triethylamine (30:10:1) as eluent to afford 2-(pyridin-3-yl)propan-2-ol (1.26 g, 46% yield) as an oil. Its 1H-NMR (CDCl3) data were as follows: δ 1.58 (6H, s, CMe2), 7.22 (1H, m, Py 5-H), 7.85 (1H, m, Py 4-H), 8.32 (1H, m, Py 6-H), 8.65 (1H, m, Py 2-H); Mass Spectrum (MS) m/z 137 (M+).

References

[1] Patent: US5595995, 1997, A

2-(Pyridin-3-yl)propan-2-ol Preparation Products And Raw materials

Raw materials

Preparation Products

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