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2-nitro-6-(trifluoromethyl)phenol

Product Name
2-nitro-6-(trifluoromethyl)phenol
CAS No.
1548-62-5
Chemical Name
2-nitro-6-(trifluoromethyl)phenol
Synonyms
2-nitro-6-(trifluoromethyl)phenol;Phenol, 2-nitro-6-(trifluoromethyl)-;2-Hydroxy-3-nitrobenzotrifluoride99%;2-Hydroxy-3-(trifluoromethyl)nitrobenzene, 2-Nitro-6-(trifluoromethyl)phenol
CBNumber
CB81984514
Molecular Formula
C7H4F3NO3
Formula Weight
207.11
MOL File
1548-62-5.mol
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2-nitro-6-(trifluoromethyl)phenol Property

Melting point:
71.2-72.0 °C
Boiling point:
195.1±35.0 °C(Predicted)
Density 
1.554±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
crystalline solid
pka
5.23±0.10(Predicted)
color 
Bright yellow
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Safety

HS Code 
2908990000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
N901360
Product name
2-Nitro-6-(trifluoromethyl)phenol
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
N901360
Product name
2-Nitro-6-(trifluoromethyl)phenol
Packaging
500mg
Price
$220
Updated
2021/12/16
Apolloscientific
Product number
PC5266
Product name
2-Hydroxy-3-nitrobenzotrifluoride
Purity
99%
Packaging
1g
Price
$131
Updated
2021/12/16
SynQuest Laboratories
Product number
4854-3-18
Product name
2-Hydroxy-3-nitrobenzotrifluoride
Purity
99%
Packaging
1g
Price
$144
Updated
2021/12/16
Apolloscientific
Product number
PC5266
Product name
2-Hydroxy-3-nitrobenzotrifluoride
Purity
99%
Packaging
5g
Price
$493
Updated
2021/12/16
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2-nitro-6-(trifluoromethyl)phenol Chemical Properties,Usage,Production

Synthesis

444-30-4

1548-62-5

17A. Synthesis of 2-nitro-6-(trifluoromethyl)phenol Concentrated nitric acid (1.5 mL) was added slowly and dropwise to a solution of commercially available 2-trifluoromethylphenol (2.5 g, 15.42 mmol) in acetic acid (3 mL) at 0 °C. The reaction mixture was stirred at room temperature for 10 min. After the dropwise addition was completed, the reaction mixture was continued to be stirred at 0°C for 5 minutes, then brought to room temperature and stirred for 10 minutes. Upon completion of the reaction, the mixture was poured into ice water and extracted with ether (3×). The ether extracts were combined, washed sequentially with water and saturated saline, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by silica gel column chromatography with 0 to 10% ethyl acetate/hexane as eluent to afford the target product 2-nitro-6-(trifluoromethyl)phenol (1.4 g, 44% yield).

References

[1] Patent: US5886044, 1999, A
[2] Patent: US5780483, 1998, A
[3] Patent: US6262113, 2001, B1
[4] Patent: US2004/19063, 2004, A1
[5] Patent: US2004/181064, 2004, A1

2-nitro-6-(trifluoromethyl)phenol Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-nitro-6-(trifluoromethyl)phenol manufacturers

Career Henan Chemical Co
Product
2-nitro-6-(trifluoromethyl)phenol 1548-62-5
Price
US $5.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2020-01-12

1548-62-5, 2-nitro-6-(trifluoromethyl)phenolRelated Search:


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  • 2-Hydroxy-3-nitrobenzotrifluoride99%
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  • 1548-62-5