ChemicalBook > CAS DataBase List > 4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile

4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile

Product Name
4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile
CAS No.
114772-55-3
Chemical Name
4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile
Synonyms
Losartan Impurity 8;1'-Biphenyl]-2-carbonitrile;Benzene,1,3,5-tribromo-2,4,10-trimethyl-;4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-;Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan;4'-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1;2-[4-[[2-butyl-4-chloro-5-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]benzonitrile;4′-(2-butyl-4-chloro-5-hydroxyMethyliMidzole-1-ylMethyl)- biphenyl-2-carbonitrile;4'-{[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl}biphenyl-2-carbonitrile;2-(4-{[2-Butyl-4-chloro-5-(hydroxymethyl)imidazolyl]methyl} phenyl)benzene carbonitrile
CBNumber
CB82103743
Molecular Formula
C22H22ClN3O
Formula Weight
379.88
MOL File
114772-55-3.mol
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4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Property

Melting point:
157-158°C
Boiling point:
605.6±55.0 °C(Predicted)
Density 
1.19
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Ethyl Acetate (Slightly)
pka
13.66±0.10(Predicted)
form 
Solid
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D297670
Product name
Des[2’-(1H-tetrazol-5-yl)]2-Cyanolosartan
Packaging
500mg
Price
$145
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB152696
Product name
4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-imidazol-1-yl)methyl]-1,1'-biphenyl-2-carbonitrile
Packaging
10mg
Price
$203
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB152696
Product name
4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-imidazol-1-yl)methyl]-1,1'-biphenyl-2-carbonitrile
Packaging
25mg
Price
$405
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0027214
Product name
LOSARTAN POTASSIUM RELATED COMPOUND B
Purity
95.00%
Packaging
5MG
Price
$505.95
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB152696
Product name
4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-imidazol-1-yl)methyl]-1,1'-biphenyl-2-carbonitrile
Packaging
50mg
Price
$704
Updated
2021/12/16
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4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Chemical Properties,Usage,Production

Uses

Des[2’-(1H-tetrazol-5-yl)] 2-Cyanolosartan is a derivative of Losartan Potassium (L470500), a an angiotensin II antagonist and is commonly used to significantly reduce risk of new onset atrial fibrillation and associated stroke in high-risk patients.

4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Suppliers

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114772-55-3, 4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrileRelated Search:


  • 4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile
  • 4′-(2-butyl-4-chloro-5-hydroxyMethyliMidzole-1-ylMethyl)- biphenyl-2-carbonitrile
  • 2-(4-{[2-Butyl-4-chloro-5-(hydroxymethyl)imidazolyl]methyl} phenyl)benzene carbonitrile
  • Losartan Impurity 8
  • Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan
  • 2-[4-[[2-butyl-4-chloro-5-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]benzonitrile
  • 1'-Biphenyl]-2-carbonitrile
  • 4'-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1
  • 4'-{[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl}biphenyl-2-carbonitrile
  • [1,1'-Biphenyl]-2-carbonitrile, 4'-[[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl]-
  • 4'-[(2-BUTYL-4-CHLORO-5-HYDROXYMETHYL-1H-IMIDAZOL-1-YL)METHYL]-1,1'-BIPHENYL-2-CARBONITRILE 114772-55-3
  • Benzene,1,3,5-tribromo-2,4,10-trimethyl-
  • Losartan Related Compound B 4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1- yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile
  • 4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-
  • 4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-imidazol-1-yl)methyl]-1,1'-biphenyl-2-carbonitrile
  • 114772-55-3
  • Losartan Potassium