Piperiacetildenafil
- Product Name
- Piperiacetildenafil
- CAS No.
- 147676-50-4
- Chemical Name
- Piperiacetildenafil
- Synonyms
- J2.357.565E;Piperiacetidenafil;Piperiacetildenafi;Piperiacetildenafil;Piperidinohongdenafil;Apremilast Impurity 109;Piperidino-acetildenafil;Piperidino acetildenafil;Piperiacetildenafil ISO 9001:2015 REACH;5-(2-Ethoxy-5-piperidinoacetylphenyl)-1-Methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyriMidin-7-one
- CBNumber
- CB82104225
- Molecular Formula
- C24H31N5O3
- Formula Weight
- 437.53
- MOL File
- 147676-50-4.mol
Piperiacetildenafil Property
- Melting point:
- 149-152oC
- Density
- 1.29±0.1 g/cm3(Predicted)
- storage temp.
- Refrigerator
- solubility
- Chloroform (Sparingly), Methanol (Slightly)
- pka
- 10.09±0.20(Predicted)
- form
- Solid
- color
- White to Off-White
N-Bromosuccinimide Price
- Product number
- P481480
- Product name
- Piperiacetildenafil
- Packaging
- 5mg
- Price
- $175
- Updated
- 2021/12/16
- Product number
- P481480
- Product name
- Piperiacetildenafil
- Packaging
- 25mg
- Price
- $790
- Updated
- 2021/12/16
- Product number
- APN0000743
- Product name
- PIPERIACETILDENAFIL
- Purity
- 95.00%
- Packaging
- 2MG
- Price
- $729.3
- Updated
- 2021/12/16
- Product number
- APN0000743
- Product name
- PIPERIACETILDENAFIL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $896.61
- Updated
- 2021/12/16
- Product number
- CM290040
- Product name
- 5-(2-Ethoxy-5-(2-(piperidin-1-yl)acetyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
- Purity
- 97%
- Packaging
- 10mg
- Price
- $374
- Updated
- 2021/12/16
Piperiacetildenafil Chemical Properties,Usage,Production
Uses
Piperiacetildenafil is an intermediate in the preparation of pyrazolopyrimidinones used in male sexual enhancement formulas
Synthesis
Piperacetildenafil was prepared as follows: piperidine (0.22 ml, 0.0022 mol) was added to a stirred 5-(5-bromoacetyl-2-ethoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3 -d]pyrimidin-7- one (Preparation 8, 0.95 g, 0.0022 mol) and anhydrous potassium carbonate (0.6 g , 0.0044 mol) in acetonitrile (50 ml). After 18 h, the mixture was evaporated under vacuum, the residue was dissolved in water (50 ml) and the solution was extracted with ethyl acetate (3 x 30 ml). The organic extracts were combined, washed with brine (3 x 20 ml), dried (Na2SO4 ) and vacuum evaporated. The resulting yellow solid was chromatographically separated on silica gel (12 g) using an elution gradient of methanol in dichloromethane (0-2% methanol) to give an off-white solid. Crystallization with ethyl acetate-hexane gave the title compound piperacetildenafil as an off-white powder (0.27 g, 28%), m.p.
Piperiacetildenafil Preparation Products And Raw materials
Raw materials
Preparation Products
Piperiacetildenafil Suppliers
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View Lastest Price from Piperiacetildenafil manufacturers
- Product
- Piperiacetildenafil 147676-50-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 10g
- Purity
- 99.0%+
- Supply Ability
- 100 tons
- Release date
- 2019-12-25