ChemicalBook > CAS DataBase List > 2-bromo-5-methoxy-4-methylaniline

2-bromo-5-methoxy-4-methylaniline

Product Name
2-bromo-5-methoxy-4-methylaniline
CAS No.
532440-88-3
Chemical Name
2-bromo-5-methoxy-4-methylaniline
Synonyms
2-bromo-5-methoxy-4-methylaniline;2-Bromo-5-methoxy-4-methyl-phenylamine;Benzenamine, 2-bromo-5-methoxy-4-methyl-
CBNumber
CB82122252
Molecular Formula
C8H10BrNO
Formula Weight
216.08
MOL File
532440-88-3.mol
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2-bromo-5-methoxy-4-methylaniline Property

Melting point:
75-77°
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
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Safety

HazardClass 
IRRITANT
HS Code 
2922290090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H311Toxic in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
B699690
Product name
2-Bromo-5-methoxy-4-methylaniline
Packaging
500mg
Price
$200
Updated
2021/12/16
TRC
Product number
B699690
Product name
2-Bromo-5-methoxy-4-methylaniline
Packaging
50mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
9390CZ
Product name
2-Bromo-5-methoxy-4-methylaniline
Packaging
25g
Price
$1342
Updated
2021/12/16
Matrix Scientific
Product number
048218
Product name
2-Bromo-5-methoxy-4-methylaniline
Purity
>95%
Packaging
5g
Price
$600
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0043558
Product name
2-BROMO-5-METHOXY-4-METHYLANILINE
Purity
95.00%
Packaging
1G
Price
$771.89
Updated
2021/12/16
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2-bromo-5-methoxy-4-methylaniline Chemical Properties,Usage,Production

Synthesis

144-55-8

16452-01-0

532440-88-3

General procedure for the synthesis of 2-bromo-5-methoxy-4-methylaniline from sodium bicarbonate and 3-methoxy-4-methylaniline: to a solution of 3-methoxy-4-methylaniline (8.19 g, 59.71 mmol) in dichloromethane (200 mL) was added tetrabutylammonium tribromide (28.79 g, 59.71 mmol) and the reaction mixture was stirred at room temperature for 2.5 hours. Upon completion of the reaction, aqueous sodium bicarbonate was added for neutralization and the organic layer was separated. The aqueous layer was further extracted with dichloromethane, and the organic phases were combined, washed sequentially with water and brine, dried with anhydrous magnesium sulfate, filtered and concentrated. The residue was purified by silica gel column chromatography (eluent: hexane solution of 20% ethyl acetate) to afford 11.05 g of 2-bromo-5-methoxy-4-methylaniline in 85% yield. The product was characterized by 1H NMR (300 MHz, CDCl3): δ 2.09 (s, 3H), 3.75 (s, 3H), 3.95 (br s, 1H), 6.27 (s, 1H), 7.13 (s, 1H).

References

[1] Patent: US2003/144329, 2003, A1

2-bromo-5-methoxy-4-methylaniline Preparation Products And Raw materials

Raw materials

Preparation Products

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2-bromo-5-methoxy-4-methylaniline Suppliers

China 33 India 1 United Kingdom 1 United States 6 Global 41
Alchem Pharmtech,Inc.
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8485655694
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sales@alchempharmtech.com
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United States
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63687
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Aladdin Scientific
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Email
tp@aladdinsci.com
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United States
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52923
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Aceschem Inc.
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+1-817863-6948 +1-（817）863-6948
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sales@aceschem.com
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United States
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19632
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Synthonix Inc
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info@synthonix.com
Country
United States
ProdList
6872
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Combi-Blocks Inc.
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sales@combi-blocks.com
Country
United States
ProdList
6618
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Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80

532440-88-3, 2-bromo-5-methoxy-4-methylanilineRelated Search:


  • 2-bromo-5-methoxy-4-methylaniline
  • 2-Bromo-5-methoxy-4-methyl-phenylamine
  • Benzenamine, 2-bromo-5-methoxy-4-methyl-
  • 532440-88-3