11BETA-13, 14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA
- Product Name
- 11BETA-13, 14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA
- CAS No.
- 107615-77-0
- Chemical Name
- 11BETA-13, 14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA
- Synonyms
- VKTIONYPMSCHQI-KGILNJEGSA-N;11β-13,14-dihydro-15-keto Prostaglandin F2α;11β-13,14-dihydro-15-keto Prostaglandin F2α;11BETA-13, 14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA;9ALPHA, 11BETA-DIHYDROXY-15-OXO-PROST-5Z-EN-1-OIC ACID
- CBNumber
- CB8213295
- Molecular Formula
- C20H34O5
- Formula Weight
- 354.48
- MOL File
- 107615-77-0.mol
11BETA-13, 14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA Property
- solubility
- 10 mM Na2CO3: >6.5 mg/ml (from PGF2a); DMF: >100 mg/ml (from PGF2a); DMSO: >100 mg/ml (from PGF2a); Ethanol: >100 mg/ml (from PGF2a); PBS pH 7.2: >10 mg/ml (from PGF2a)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
H336May cause drowsiness or dizziness
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 16540
- Product name
- 11β-13,14-dihydro-15-keto Prostaglandin F2α
- Purity
- ≥95%
- Packaging
- 50μg
- Price
- $57
- Updated
- 2024/03/01
- Product number
- 16540
- Product name
- 11β-13,14-dihydro-15-keto Prostaglandin F2α
- Purity
- ≥95%
- Packaging
- 100μg
- Price
- $107
- Updated
- 2024/03/01
- Product number
- 16540
- Product name
- 11β-13,14-dihydro-15-keto Prostaglandin F2α
- Purity
- ≥95%
- Packaging
- 500μg
- Price
- $437
- Updated
- 2024/03/01
- Product number
- SHG0004712
- Product name
- 9ALPHA,11BETA-DIHYDROXY-15-OXO-PROST-5Z-EN-1-OIC ACID
- Purity
- 98.00%
- Packaging
- 1MG
- Price
- $1660.89
- Updated
- 2021/12/16
- Product number
- MT-09902
- Product name
- 9alpha,11beta-Dihydroxy-15-oxo-prost-5Z-en-1-oicacid
- Purity
- 98%
- Packaging
- 0.001g
- Price
- $608
- Updated
- 2021/12/16
11BETA-13, 14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA Chemical Properties,Usage,Production
Description
11β-13,14-dihydro-15-keto PGF2α is a metabolite of PGD2 in the 15-hydroxy PGDH pathway.1,2 Infusion or inhalation of tritiated PGD2 in normal males results in the appearance of peak levels of both 11β-PGF2α, as the immediate product, and 11β-13,14-dihydro-15-keto PGF2α in the plasma within 10 minutes.1 Homogenates of human lung metabolize PGD2 first to 11β-PGF2α and then to 11β-15-keto-PGF2α in the presence of NAD+, but not 11β-13,14-dihydro-15-keto PGF2α.2 Guinea pig liver and kidney homogenates metabolize PGD2 to 11β-13,14-dihydro-15-keto PGF2α, via 11β-PGF2α, in the presence of NAD+ and NADP+.2
Definition
ChEBI: 11beta-13,14-dihydro-15-keto-PGF2alpha is a prostanoid.
References
1. Robinson, C., Hardy, C.C., and Holgate, S.T. The metabolism of prostaglandin D2 after inhalation or intravenous infusion in normal men Biochim. Biophys. Acta 963(2),151-161(1988).
2. Robinson, C., Herbert, C.A., Bedwell, S., et al. The metabolism of prostaglandin D2. Evidence for the sequential conversion by NADPH and NAD+ dependent pathways Biochem. Pharmacol. 38(19),3267-3271(1989).
11BETA-13, 14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA Preparation Products And Raw materials
Raw materials
Preparation Products
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