SILTHIOFAM
- Product Name
- SILTHIOFAM
- CAS No.
- 175217-20-6
- Chemical Name
- SILTHIOFAM
- Synonyms
- MON65500;LATITUDE;SILTHIOFAM;Silthiopham;Silthiofarm;silthiofam 98%;Silthiofam [iso];silthiofam (bsi,iso);C16947000 Silthiofam;Silthiofam, 10 μg /μL in hexane
- CBNumber
- CB8213578
- Molecular Formula
- C13H21NOSSi
- Formula Weight
- 267.46
- MOL File
- 175217-20-6.mol
SILTHIOFAM Property
- Boiling point:
- 303.2±42.0 °C(Predicted)
- Density
- 1.01±0.1 g/cm3(Predicted)
- Flash point:
- 12°C
- pka
- 15.11±0.46(Predicted)
- Major Application
- agriculture
environmental - InChI
- 1S/C13H21NOSSi/c1-7-8-14-12(15)11-9(2)10(3)16-13(11)17(4,5)6/h7H,1,8H2,2-6H3,(H,14,15)
- InChIKey
- MXMXHPPIGKYTAR-UHFFFAOYSA-N
- SMILES
- Cc1sc(c(c1C)C(=O)NCC=C)[Si](C)(C)C
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H373May cause damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P273Avoid release to the environment.
P314Get medical advice/attention if you feel unwell.
P391Collect spillage. Hazardous to the aquatic environment
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 32498
- Product name
- Silthiofam
- Purity
- PESTANAL
- Packaging
- 25mg
- Price
- $217
- Updated
- 2025/07/31
- Product number
- 466094
- Product name
- Silthiofam
- Packaging
- 2.5mg
- Price
- $460
- Updated
- 2021/12/16
- Product number
- S465070
- Product name
- Silthiofam
- Packaging
- 10mg
- Price
- $595
- Updated
- 2021/12/16
- Product number
- CDX-S0049-M025
- Product name
- Silthiopham
- Purity
- ≥98%(HPLC)
- Packaging
- 25mg
- Price
- $129
- Updated
- 2021/12/16
- Product number
- PST0000472
- Product name
- LATITUDE
- Purity
- 98.00%
- Packaging
- 100ML
- Price
- $2739
- Updated
- 2021/12/16
SILTHIOFAM Chemical Properties,Usage,Production
Chemical Properties
Silithiamide is white granular solid, melting point is 86.1~88.3℃, vapor pressure(20℃)8.1×10mPa. kow lgP=3.72(20℃), Henry's constant 5.4×10-1 Pa -m3/ mol, relative density 1.07(20℃). Solubility in water (20°C) 39.9 mg/L. Solubility in organic solvents (20°C, g/L): n-heptane 15.5, xylene, 1,2-dichloromethane, methanol, acetone, and ethyl acetate were all greater than 250. Stability DT50 (25°C): 6ld (pH 5), 448d (pH 7), 314d (pH 9).
Uses
Silthiofam is a fungicide. It is derived from 3-Chloro-2-butanone (C366895), which is widely used in the chemical and pharmaceutical industries as an intermediate or starting material (for example its use in a one-pot synthesis of γ-iminolactones). Also, it is derived from 2-Amino-4,5-dimethyl-3-thiophenecarboxylic Acid Ethyl Ester (A605165), which is used in the preparation triazine and pyrimidine derivatives as anti-inflammatory and analgesic agents. Also used in the synthesis of antioxidants through heteroaryl amines as well as CB2 cannabinoid receptor partial agonists.
Definition
ChEBI: A monocarboxylic acid amide obtained by formal condensation of the carboxy group from 4,5-dimethyl-2-(trimethylsilyl)thiophene-3-carboxlic acid with the amino group of allylamine. A fungicide seed dressing for cereals used mainly to control 'take-all'.
Synthesis
Silthiofam is synthesized in three steps. 1) Preparation of methyl trimethylsilylpropynoate: Trimethylsilylacetylene reacts with n-butyllithium, then with methyl chloroformate. Work-up and purification yield the product. 2) Preparation of methyl 4,5-dimethyl-2-(trimethylsilyl)thiophene-3-carboxylate: The product from step 1 reacts with 3-mercapto-2-butanone in toluene with sodium methoxide under reflux. Work-up and purification give the product. 3) Preparation of the final product: The ester from step 2 reacts with excess allylamine catalyzed by TBD under heating and reflux. Work-up yields silthiofam.
SILTHIOFAM Preparation Products And Raw materials
Raw materials
Preparation Products
SILTHIOFAM Suppliers
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- China
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- 0086-571-89925065
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- United States
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View Lastest Price from SILTHIOFAM manufacturers
- Product
- SILTHIOFAM 175217-20-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98
- Supply Ability
- 10000KGS
- Release date
- 2025-12-11
- Product
- silthiopham 175217-20-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- 20tons
- Release date
- 2024-07-31
- Product
- silthiofam 175217-20-6
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- Min98% HPLC
- Supply Ability
- g/kg/ton
- Release date
- 2020-02-11