ChemicalBook > CAS DataBase List > 3β-Hydroxyurs-12,19-dien-28-oic acid

3β-Hydroxyurs-12,19-dien-28-oic acid

Product Name: 3β-Hydroxyurs-12,19-dien-28-oic acid
CAS No.: 6812-98-2
Chemical Name: 3β-Hydroxyurs-12,19-dien-28-oic acid
Synonyms: Ursa-12;3β-Hydroxyurs-12;Sanguisorbigenin;Tomentosolic acid;19-dien-28-oic acid;19-Dehydroursolic acid;Ursa-12,19-dien-28-oic acid;Sanguisorbigenin, 10 mM in DMSO;3β-Hydroxyurs-12,19-dien-28-oic acid;Ursa-12,19-dien-28-oic acid, 3-hydroxy-, (3β)-
CBNumber: CB82143356
Molecular Formula: C30H46O3
Formula Weight: 454.7
MOL File: 6812-98-2.mol

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3β-Hydroxyurs-12,19-dien-28-oic acid Property

Melting point:: 267-268 °C (decomp)
Boiling point:: 563.4±50.0 °C(Predicted)
Density: 1.11±0.1 g/cm3(Predicted)
pka: 4.49±0.70(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom

Product number: CFN91139
Product name: Sanguisorbigenin
Purity: ≥98%
Packaging: 5mg
Price: $413
Updated: 2021/12/16

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3β-Hydroxyurs-12,19-dien-28-oic acid Chemical Properties,Usage,Production

Uses

Sanguisorbigenin is a natural antibacterial agent that inhibits methicillin-resistant S. aureus (MRSA)[1].

Biological Activity

Sanguisorbigenin is a natural antibacterial agent that inhibits methicillin-resistant S. aureus (MRSA)[1]. The minimal inhibitory concentration values of Sanguisorbigenin against six strains of S. aureus are in the range of 12.5-50 μg/mL[1]. The expression of blaR1, mecA and blaZ is significantly inhibited in MRSA in a dose-dependent manner when it is treated with sub-MIC (1.56-6.25 μg/mL) concentrations of Sanguisorbigenin. Sanguisorbigenin remarkably reduces the gene expression of mecA. Sanguisorbigenin has a potent antibacterial effect and could effectively reverse the sense of antibiotics by inhibiting the mecA expression and decrease PBP2a expression[1].

References

[1]. S Wang, et al. Antibacterial activity and synergy of antibiotics with sanguisorbigenin isolated from Sanguisorba officinalis L. against methicillin-resistant Staphylococcus aureus. Lett Appl Microbiol. 2021 Mar;72(3):238-244.

3β-Hydroxyurs-12,19-dien-28-oic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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6812-98-2, 3β-Hydroxyurs-12,19-dien-28-oic acidRelated Search:

3β-Hydroxyurs-12,19-dien-28-oic acid

Sanguisorbigenin

Tomentosolic acid

Ursa-12,19-dien-28-oic acid, 3-hydroxy-, (3β)-

19-Dehydroursolic acid

19-dien-28-oic acid

3β-Hydroxyurs-12

Ursa-12

Ursa-12,19-dien-28-oic acid

PBP2a,mecA,Bacterial,Sanguisorbigenin,MRSA,inhibit,Inhibitor,antibacterial

Sanguisorbigenin, 10 mM in DMSO

6812-98-2