ChemicalBook > CAS DataBase List > N-(2-AMINOETHYL)GLYCINE

N-(2-AMINOETHYL)GLYCINE

Product Name
N-(2-AMINOETHYL)GLYCINE
CAS No.
24123-14-6
Chemical Name
N-(2-AMINOETHYL)GLYCINE
Synonyms
AEG;H-AEG-OH;H-NHETGLY-OH;Aminoethylglycine;2-((2-Aminoethyl);N-AMINOETHYL-GLYCINE;N-b-Aminoethyl-Gly-OH;N-β-Aminoethyl-Gly-OH;(2-aminoethyl)glycine;3,6-Diazahexanoic acid
CBNumber
CB8217697
Molecular Formula
C4H10N2O2
Formula Weight
118.13
MOL File
24123-14-6.mol
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N-(2-AMINOETHYL)GLYCINE Property

Melting point:
140-143°C
Boiling point:
290℃
Density 
1.161
Flash point:
129℃
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
Methanol (Slightly, Sonicated), Water (Slightly)
pka
2.21±0.10(Predicted)
form 
Solid
color 
White to Off-White
Water Solubility 
very faint turbidity
Stability:
Incompatible with strong oxidizing agents.
InChI
InChI=1S/C4H10N2O2/c5-1-2-6-3-4(7)8/h6H,1-3,5H2,(H,7,8)
InChIKey
PIINGYXNCHTJTF-UHFFFAOYSA-N
SMILES
C(O)(=O)CNCCN
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38-36
Safety Statements 
24/25-36-26
HS Code 
2922499990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CDS000144
Product name
[(2-Aminoethyl)amino]acetic acid
Purity
AldrichCPR
Packaging
250MG
Price
$391
Updated
2024/03/01
TCI Chemical
Product number
A1153
Product name
N-(2-Aminoethyl)glycine
Purity
>97.0%(T)
Packaging
1g
Price
$553
Updated
2025/07/31
TCI Chemical
Product number
A1153
Product name
N-(2-Aminoethyl)glycine
Purity
>97.0%(T)
Packaging
100mg
Price
$132
Updated
2025/07/31
TRC
Product number
A608975
Product name
N-(2-Aminoethyl)glycine
Packaging
25g
Price
$640
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
6550
Product name
N-(2-Aminoethyl)glycine
Packaging
1g
Price
$820
Updated
2021/12/16
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N-(2-AMINOETHYL)GLYCINE Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

2-((2-Aminoethyl)amino)acetic acid is a Glycine.html" class="link-product" target="_blank">Glycine (HY-Y0966) derivative[1].

Synthesis

107-15-3

79-11-8

24123-14-6

The general procedure for the synthesis of 2-((2-aminoethyl)amino)acetic acid from ethylenediamine and chloroacetic acid is as follows: Example 8: Preparation of [(2-aminoethyl)amino]acetic acid (3) in DMSO 1. Preparation of chloroacetic acid solution: chloroacetic acid (500.0 g, 5.29 mol) was dissolved in DMSO (515.6 g). 2. Reaction setup: ethylenediamine (3537mL, 52.9mol) was added to a 5L flask equipped with a nitrogen inlet, mechanical stirrer, thermocouple and peristaltic metering pump. Begin cooling with ice water. 3. Dropwise addition of chloroacetic acid solution: chloroacetic acid solution in DMSO was slowly added to ethylenediamine via a metering pump. The reaction conditions are shown in Table 1. Table 1: Reaction conditions during addition of chloroacetic acid solution to ethylenediamine | No. | Time | Temperature (°C) | Pressure (Torr) | |------|--------|----------|-----------| | 1 | 10:51 | 17 | - | | 2 | 11:28 | 18 | - | | 3 | 12:18 | 16 | 720 | | 4 | 13:38 | 11 | 625 | 4 | 13:38 | 11 | 625 | 5 | 14:35 | 12 | 550 | 4 | 13:38 | 11 | 625 | 4 6 | 15:17 | 10 | 490 | 7 | 16:08 | 16:08 | 7 | 16:08 | 8 | 420 | 8 | 8:59 | 8 | 8:59 | 8 | 8:59 | 8 | 8:59 | 8 | 8:59* | 19 | 0 | *Time represents the next day. 4. Concentration of reaction mixture: The reaction mixture was concentrated by rotary evaporation (50-60 °C, 14-21 Torr) to remove ethylenediamine. The total amount of distillate collected was 2400mL. 5. Toluene treatment: Toluene (900 mL) was added to the residue and the mixture was further concentrated by rotary evaporation (60 °C, 30 Torr). 6. Transfer and cooling: The residue was transferred to a 5L flask using DMSO (3kg). The internal temperature was 28°C and the mixture was cloudy. Cooling (ice/water) was started. 7. Overnight stirring: the reaction mixture was stirred overnight. 8. filtration and washing: the resulting suspension was filtered through filter paper. The flask and solid were washed with DMSO (2 x 500mL). The solid was subsequently washed with isopropanol (2 x 500mL) and tert-butyl methyl ether (2 x 500mL). 9. Drying: The solid was dried at ambient temperature under high vacuum for 18 h. 10. 10. Product collection: 2-((2-aminoethyl)amino)acetic acid (3) was obtained as a white solid (480.4 g, 4.07 mol) in 77% yield.

References

[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368

N-(2-AMINOETHYL)GLYCINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from N-(2-AMINOETHYL)GLYCINE manufacturers

Henan Fengda Chemical Co., Ltd
Product
N-(2-AMINOETHYL)GLYCINE 24123-14-6
Price
US $34.00-1.10/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-25
Career Henan Chemical Co
Product
N-(2-AMINOETHYL)GLYCINE 24123-14-6
Price
US $100.00/KG
Min. Order
2KG
Purity
99%
Supply Ability
5tons
Release date
2018-07-23

24123-14-6, N-(2-AMINOETHYL)GLYCINERelated Search:


  • H-NHETGLY-OH
  • H-AEG-OH
  • ETHYLENEDIAMINE-N-ACETIC ACID
  • ETHYLENEDIAMINE-N-MONOACETIC ACID
  • N-(2-AMINOETHYL)GLYCINE
  • N-BETA-AMINOETHYL-GLYCINE
  • N-BETA-AMINOETHYL-GLY-OH
  • N-AMINOETHYL-GLYCINE
  • Aminoethylglycine
  • AEG Ethylenediamine-N-acetic Acid
  • N-b-Aminoethyl-Gly-OH
  • AEG
  • (2-Aminoethylamino)acetic acid
  • Glycine,N-(2-aminoethyl)-
  • 2-((2-Aminoethyl)
  • N-β-Aminoethyl-Glycine≥ 98% (TLC)
  • N-β-Aminoethyl-Gly-OH
  • 2-(2-aMinoethylaMino)acetic acid
  • 3,6-Diazahexanoic acid
  • Ethylenediaminemonoacetic acid
  • N-(2-Aminoethyl)glycine&gt
  • 2-(2-aminoethylamino)aceticaci
  • N-(2-AMINOETHYL)GLYCINE USP/EP/BP
  • N-β-Aminoethyl-Glycine
  • (2-aminoethyl)glycine
  • 24123-14-6
  • Amino Acids 13C, 2H, 15N
  • Amino Acids & Derivatives