2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione

Product Name
2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione
CAS No.
19667-37-9
Chemical Name
2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione
Synonyms
Rivaroxaban Impurity 120;N-(3-Chloro-2-hydroxypropyl)phthalimide;2-(3-Chloro-2-hydroxypropyl)isoindoline-1,3-dione;2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione;1H-Isoindole-1,3(2H)-dione, 2-(3-chloro-2-hydroxypropyl)-
CBNumber
CB82356277
Molecular Formula
C11H10ClNO3
Formula Weight
239.65
MOL File
19667-37-9.mol
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2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Property

Melting point:
95-96.5 °C
Boiling point:
405.4±35.0 °C(Predicted)
Density 
1.444±0.06 g/cm3(Predicted)
pka
13.25±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S413054
Product name
N-(3-CHLORO-2-HYDROXYPROPYL)-PHTHALIMIDE
Purity
AldrichCPR
Packaging
50mg
Price
$179
Updated
2024/03/01
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2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Chemical Properties,Usage,Production

Uses

2-(3-Chloro-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione has been used in yeast biosynthesis of (S)-adrenergic β-blockers by stereoselective reduction of haloketones. It has also been used in a validated LC-?MS?/MS method for the determination of three genotoxic impurities in rivaroxaban drug substance.

2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Suppliers

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Shanghai ChuangYan Chemical Technology Co., Ltd.
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19667-37-9, 2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dioneRelated Search:


  • 2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione
  • N-(3-Chloro-2-hydroxypropyl)phthalimide
  • Rivaroxaban Impurity 120
  • 1H-Isoindole-1,3(2H)-dione, 2-(3-chloro-2-hydroxypropyl)-
  • 2-(3-Chloro-2-hydroxypropyl)isoindoline-1,3-dione
  • 19667-37-9
  • 19667-37-2