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TAFENOQUINE SUCCINATE

Product Name
TAFENOQUINE SUCCINATE
CAS No.
106635-81-8
Chemical Name
TAFENOQUINE SUCCINATE
Synonyms
WR-238605;Krintafel;SB-252263;SB 252263AX;Wr238605 succinate;Tafenoquine Succinate;N-[2,6-Dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl]pentane-1,4-diamine;Parasite,inhibit,WR-238605,Inhibitor,Tafenoquine Succinate,Tafenoquine,WR238605,WR 238605;N4-(2,6-Dimethoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)quinolin-8-yl)pentane-1,4-diamine succinate(1:1);8-[(4-Amino-1-methylbutyl)amino]-2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinoline succinate
CBNumber
CB82360531
Molecular Formula
C28H34F3N3O7
Formula Weight
581.5806696
MOL File
106635-81-8.mol
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TAFENOQUINE SUCCINATE Property

Melting point:
146-149°
storage temp. 
2-8°C
solubility 
DMSO: soluble5mg/mL (clear solution)
form 
powder
color 
white to beige
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Safety

WGK Germany 
3
Toxicity
LD50 in male, female rats (mg/kg): 102, 71 i.p.; 429, 416 orally (LaMontagne)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0396
Product name
Tafenoquine succinate
Purity
≥95% (HPLC)
Packaging
10mg
Price
$93.4
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0396
Product name
Tafenoquine succinate
Purity
≥95% (HPLC)
Packaging
50mg
Price
$380
Updated
2024/03/01
TRC
Product number
T004760
Product name
Tafenoquine succinate
Packaging
10mg
Price
$275
Updated
2021/12/16
ChemScene
Product number
CS-0083862
Product name
Tafenoquine succinate
Purity
99.98%
Packaging
10mg
Price
$290
Updated
2021/12/16
ChemScene
Product number
CS-0083862
Product name
Tafenoquine succinate
Purity
99.98%
Packaging
5mg
Price
$190
Updated
2021/12/16
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TAFENOQUINE SUCCINATE Chemical Properties,Usage,Production

Uses

Tatenoquine is a new 8-aminoquinoline with an improved therapeutic index and safety profile as compared to primaquine (P733500).Tafenoquine has the potential to become a widely used drug in the prevention and treatment of malaria infection and could replace some currently used drugs as resistant strains of Plasmodium species increase.

Uses

Tafenoquine succinate is a new 8-aminoquinoline with an improved therapeutic index and safety profile as compared to primaquine (P733500).Tafenoquine has the potential to become a widely used drug in the preven tion and treatment of malaria infection and could replace some currently used drugs as resistant strains of Plasmodium species increase.

Biochem/physiol Actions

Tafenoquine is an antimalarial primaquine analog being investigated to treat and prevent Plasmodium vivax infections. It can eliminate both blood and liver stages of Plasmodium vivax. Tafenoquine has also been tested as a therapy for leishmaniasis.

TAFENOQUINE SUCCINATE Preparation Products And Raw materials

Raw materials

Preparation Products

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TAFENOQUINE SUCCINATE Suppliers

Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71
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View Lastest Price from TAFENOQUINE SUCCINATE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Tafenoquine succinate 106635-81-8
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98.0%
Supply Ability
1kg/month
Release date
2021-07-23

106635-81-8, TAFENOQUINE SUCCINATERelated Search:


  • WR-238605
  • Butanedioic acid, compd. with N(sup 4)-(2,6-dimethoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)-8-quinolinyl)-1,4-pentanediamine (1:1)
  • Wr238605 succinate
  • Tafenoquine Succinate
  • N-[2,6-Dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl]pentane-1,4-diamine
  • SB-252263
  • Krintafel
  • TAFENOQUINE SUCCINATE; WR-238605, WR 238605, WR238605, SB-252263-AAB; SB252263-AAB; SB 252263-AAB; KRINTAFEL;
  • SB 252263AX
  • 8-[(4-Amino-1-methylbutyl)amino]-2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinoline succinate
  • N4-(2,6-Dimethoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)quinolin-8-yl)pentane-1,4-diamine succinate(1:1)
  • Parasite,inhibit,WR-238605,Inhibitor,Tafenoquine Succinate,Tafenoquine,WR238605,WR 238605
  • 106635-81-8
  • C24H28F3N3O3C4H6O4