CYCLODODECYLAMINE Property

Melting point:

27-29 °C(lit.)

Boiling point:

122-124 °C7 mm Hg(lit.)

Density 

0.9093 (rough estimate)

refractive index 

1.487-1.489

Flash point:

250 °F

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

pka

10.98±0.20(Predicted)

CAS DataBase Reference

1502-03-0(CAS DataBase Reference)

EPA Substance Registry System

Cyclododecanamine (1502-03-0)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

RIDADR 

UN 3259 8/PG 3

WGK Germany 

3

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

CYCLODODECYLAMINE Chemical Properties,Usage,Production

Chemical Properties

CLEAR SLIGHTLY YELLOW LIQUID AFTER MELTING

Production Methods

Cyclododecylamine is produced by reduction of cyclododecanone oxime with sodium and an alcohol, by catalytic reduction of nitrocyclododecane with hydrogen, by Ritter reaction of cyclododecene with hydrocyanic acid, or by hydrogenation of cyclododecanone under amination conditions. The reaction of cyclododecylamine with propylene oxide leads to a product that can undergo cyclization to give the fungicide Dodemorph (BASF). The compound behaves chemically as a primary amine.

Purification Methods

It can be purified via the hydrochloride salt m 274-275o (from EtOH) or the picrate m 232-234o, and the free base is distilled preferably at water-pump vacuum [Prelog et al. Helv Chim Acta 33 365 1950].