1'-azaspiro[oxirane-2,3'-bicyclo[2.2.2]octane]

Product Name: 1'-azaspiro[oxirane-2,3'-bicyclo[2.2.2]octane]
CAS No.: 41353-91-7
Chemical Name: 1'-azaspiro[oxirane-2,3'-bicyclo[2.2.2]octane]
Synonyms: 3-Methylenequinuclidine oxide;3-Methylenequinuclidine epoxide;Spiro[oxirane-2,3'-quinuclidine];Spiro[1-azabicyclo[2.2.2]octane-3,2'-oxirane;1'-Azaspiro[oxirane-2,3'-bicyclo[2.2.2]octane;Spiro[1-azabicyclo[2.2.2]octane-3,2'-oxirane];1'-azaspiro[oxirane-2,3'-bicyclo[2.2.2]octane];(1'S,2R,4'S)-1'-azaspiro[oxirane-2,3'-bicyclo[2.2.2]octane]
CBNumber: CB82428170
Molecular Formula: C8H13NO
Formula Weight: 139.19
MOL File: 41353-91-7.mol

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1'-azaspiro[oxirane-2,3'-bicyclo[2.2.2]octane] Property

Boiling point:: 211.3±13.0 °C(Predicted)
Density: 1.17±0.1 g/cm3(Predicted)
pka: 10.43±0.20(Predicted)
form: solid
InChI: 1S/C8H13NO/c1-3-9-4-2-7(1)8(5-9)6-10-8/h7H,1-6H2
InChIKey: TYCHQBRUARUTCL-UHFFFAOYSA-N
SMILES: N12CC3(C(CC2)CC1)OC3

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Safety

WGK Germany: WGK 3
Storage Class: 11 - Combustible Solids
Hazard Classifications: Aquatic Chronic 1
Eye Irrit. 2
Skin Irrit. 2
Skin Sens. 1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P391Collect spillage. Hazardous to the aquatic environment

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PH018268
Product name: 4-Azaspiro[bicyclo[2.2.2]octane-2,2′-oxirane]
Purity: AldrichCPR
Packaging: 500MG
Price: $119
Updated: 2023/06/20

TRC

Product number: A758140
Product name: 4-Azaspiro[bicyclo[2.2.2]octane-2,2''-oxirane]
Packaging: 500mg
Price: $540
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0152541
Product name: SPIRO[1-AZABICYCLO[2.2.2]OCTANE-3,2 OXIRANE
Purity: 95.00%
Packaging: 5MG
Price: $500.18
Updated: 2021/12/16

Chemenu

Product number: CM124408
Product name: 4-azaspiro[bicyclo[2.2.2]octane-2,2''-oxirane]
Purity: 97%
Packaging: 5g
Price: $926
Updated: 2021/12/16

Chemenu

Product number: CM124408
Product name: 4-azaspiro[bicyclo[2.2.2]octane-2,2''-oxirane]
Purity: 97%
Packaging: 1g
Price: $309
Updated: 2021/12/16

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1'-azaspiro[oxirane-2,3'-bicyclo[2.2.2]octane] Chemical Properties,Usage,Production

Description

1'-Azaspiro[oxirane-2,3'-bicyclo[2.2.2]octane] (also known as Spiro[oxirane-2,3'-quinuclidine]) is a key intermediate in the synthesis of Mequitazine. Mequitazine is an antihistamine preparation, commonly used to treat bronchial asthma, allergic rhinitis, urticaria, and pruritus associated with dermatological conditions (eczema, dermatitis, pruritus).

Uses

4-Azaspiro[bicyclo[2.2.2]octane-2,2'-oxirane] is an intermediate used in the synthesis of trans-Cevimeline Hydrochloride (C283525), which is a reagent in the preparation of spiro-oxathiolane/quinuclidine sulfoxide derivative for the treatment of central nervous and cholinergic system disease or disorders.

1'-azaspiro[oxirane-2,3'-bicyclo[2.2.2]octane] Preparation Products And Raw materials

Raw materials

Preparation Products

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1'-azaspiro[oxirane-2,3'-bicyclo[2.2.2]octane] Suppliers

China 38 India 1 United States 1 Global 40

Qingdao Kingway Pharmtech Co., Ltd.

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SPIRO PHARMA

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Shanghai Zhen Li Biological Technology Co., Ltd

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Xenoah Pharmaceutical Inc.

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Jinan Yaoyan Pharmaceutical Co., Ltd.

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Shanghai silk sail pharmaceutical technology co., LTD

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Cool Pharm, Ltd

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View Lastest Price from 1'-azaspiro[oxirane-2,3'-bicyclo[2.2.2]octane] manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: Spiro[oxirane-2,3'-quinuclidine] 41353-91-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-19

Career Henan Chemical Co

Product: Spiro[oxirane-2,3'-quinuclidine] 41353-91-7
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-02-16

41353-91-7, 1'-azaspiro[oxirane-2,3'-bicyclo[2.2.2]octane]Related Search:

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Spiro[1-azabicyclo[2.2.2]octane-3,2'-oxirane]

Spiro[oxirane-2,3'-quinuclidine]

1'-azaspiro[oxirane-2,3'-bicyclo[2.2.2]octane]

3-Methylenequinuclidine epoxide

3-Methylenequinuclidine oxide

(1'S,2R,4'S)-1'-azaspiro[oxirane-2,3'-bicyclo[2.2.2]octane]

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Spiro[1-azabicyclo[2.2.2]octane-3,2'-oxirane

41353-91-7