2-AMINO-3-BROMO-5-CHLOROPYRAZINE

Product Name: 2-AMINO-3-BROMO-5-CHLOROPYRAZINE
CAS No.: 76537-18-3
Chemical Name: 2-AMINO-3-BROMO-5-CHLOROPYRAZINE
Synonyms: Amino-3-bromo-5-chloropyrazine;3-broMo-5-chloropyrazin-2-aMine;2-amine-3-bromo-5-chloropyrazin;3-Bromo-5-chloro-2-aminopyrazine;2-AMINO-3-BROMO-5-CHLOROPYRAZINE;3-Bromo-5-chloropyrazin-2-ylamine;2-Pyrazinamine, 3-bromo-5-chloro-;2-AMINO-3-BROMO-5-CHLOROPYRAZINE ISO 9001：2015 REACH
CBNumber: CB82452773
Molecular Formula: C4H3BrClN3
Formula Weight: 208.44
MOL File: 76537-18-3.mol

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2-AMINO-3-BROMO-5-CHLOROPYRAZINE Property

Boiling point:: 298.4±35.0 °C(Predicted)
Density: 1.96
refractive index: 1.66
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 0.89±0.10(Predicted)
Appearance: Light yellow to brown Solid
InChI: InChI=1S/C4H3BrClN3/c5-3-4(7)8-1-2(6)9-3/h1H,(H2,7,8)
InChIKey: ACFBUXHJONGLLF-UHFFFAOYSA-N
SMILES: C1(N)=NC=C(Cl)N=C1Br

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: A594270
Product name: 2-Amino-3-bromo-5-chloropyrazine
Packaging: 500mg
Price: $75
Updated: 2021/12/16

TRC

Product number: A594270
Product name: 2-Amino-3-bromo-5-chloropyrazine
Packaging: 1g
Price: $110
Updated: 2021/12/16

Matrix Scientific

Product number: 071152
Product name: 3-Bromo-5-chloropyrazin-2-amine
Purity: 97%
Packaging: 5g
Price: $200
Updated: 2021/12/16

Matrix Scientific

Product number: 071152
Product name: 3-Bromo-5-chloropyrazin-2-amine
Purity: 97%
Packaging: 10g
Price: $525
Updated: 2021/12/16

Matrix Scientific

Product number: 071152
Product name: 3-Bromo-5-chloropyrazin-2-amine
Purity: 97%
Packaging: 1g
Price: $65
Updated: 2021/12/16

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2-AMINO-3-BROMO-5-CHLOROPYRAZINE Chemical Properties,Usage,Production

Synthesis

33332-29-5

76537-18-3

General procedure for the synthesis of 2-amino-3-bromo-5-chloropyrazine from 2-amino-5-chloropyrazine: 2-amino-5-chloropyrazine (3 g, 23 mmol), N-bromosuccinimide (4 g, 23 mmol), and dichloromethane (100 mL) were added to a 250 mL round-bottomed flask under nitrogen protection. The reaction mixture was heated and refluxed for 1 h before being cooled to room temperature and concentrated under reduced pressure. The crude product was purified by fast column chromatography using pentane/ethyl acetate (0 to 50%) as eluent to afford 2-amino-3-bromo-5-chloropyrazine (3 g, 62% yield).1H NMR (DMSO-d6) δ 6.8-6.9 (2H, broad single peak), 8.0 (1H, single peak). Mass spectrum (ES+): m/z 210, 212.

References

[1] Journal of Medicinal Chemistry, 1997, vol. 40, # 6, p. 996 - 1004
[2] Patent: WO2006/58074, 2006, A1. Location in patent: Page/Page column 20
[3] Patent: US5866568, 1999, A
[4] Patent: US5668137, 1997, A
[5] Patent: WO2018/98499, 2018, A1. Location in patent: Page/Page column 283

2-AMINO-3-BROMO-5-CHLOROPYRAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-3-BROMO-5-CHLOROPYRAZINE Suppliers

China 110 India 1 United States 8 Global 119

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
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Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

Protheragen-ING

Tel: +16313385890
Email: info@protheragen-ing.com
Country: United States
ProdList: 3868
Advantage: 58

Aladdin Scientific

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Email: tp@aladdinsci.com
Country: United States
ProdList: 57505
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SynChem，Inc

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Email: sales@synchem.com
Country: United States
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SynQuest Laboratories, Inc.

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Country: United States
ProdList: 6871
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Matrix Scientific

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Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

AK Scientific, Inc.

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Email: sales@aksci.com
Country: United States
ProdList: 6347
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View Lastest Price from 2-AMINO-3-BROMO-5-CHLOROPYRAZINE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 2-Amino-3-bromo-5-chloropyrazine 76537-18-3
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%+
Supply Ability: 800 tons
Release date: 2020-04-29

Career Henan Chemical Co

Product: 2-AMINO-3-BROMO-5-CHLOROPYRAZINE 76537-18-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 150KG
Release date: 2019-07-02

76537-18-3, 2-AMINO-3-BROMO-5-CHLOROPYRAZINERelated Search:

3-Bromo-5-chloropyrazin-2-ylamine

Amino-3-bromo-5-chloropyrazine

2-AMINO-3-BROMO-5-CHLOROPYRAZINE

3-broMo-5-chloropyrazin-2-aMine

3-Bromo-5-chloro-2-aminopyrazine

2-Pyrazinamine, 3-bromo-5-chloro-

2-AMINO-3-BROMO-5-CHLOROPYRAZINE ISO 9001：2015 REACH

2-amine-3-bromo-5-chloropyrazin

76537-18-3