6-CYCLOPROPYL-3-PYRIDINYL BORONIC ACID PINACOL ESTER

Product Name: 6-CYCLOPROPYL-3-PYRIDINYL BORONIC ACID PINACOL ESTER
CAS No.: 893567-09-4
Chemical Name: 6-CYCLOPROPYL-3-PYRIDINYL BORONIC ACID PINACOL ESTER
Synonyms: 6-CYCLOPROPYL-3-PYRIDINYL BORONIC ACID PICOL ESTER;6-Cyclopropylpyridine-3-boronic acid pinacol ester;2-Cyclopropyl-5-pyridinyl boronic acid pinacol ester;6-CYCLOPROPYL-3-PYRIDINYL BORONIC ACID PINACOL ESTER;2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl);2-cyclopropyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine;Pyridine, 2-cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-;2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine - [C26257];6-Cyclopropylpyridine-3-boronic acid pinacol ester 6-(Cyclopropyl)pyridine-3-boronic acid pinacol ester
CBNumber: CB82453053
Molecular Formula: C14H20BNO2
Formula Weight: 245.13
MOL File: 893567-09-4.mol

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6-CYCLOPROPYL-3-PYRIDINYL BORONIC ACID PINACOL ESTER Property

Boiling point:: 354.1±30.0 °C(Predicted)
Density: 1.07±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,Store in freezer, under -20°C
pka: 5.90±0.24(Predicted)
form: solid
color: white to light yellow

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37-60
TSCA: No

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: C991640
Product name: 6-Cyclopropyl-3-pyridinylboronicacidpinacolester
Packaging: 10mg
Price: $60
Updated: 2021/12/16

TRC

Product number: C991640
Product name: 6-Cyclopropyl-3-pyridinylboronicacidpinacolester
Packaging: 50mg
Price: $185
Updated: 2021/12/16

AK Scientific

Product number: 4763AC
Product name: 2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
Packaging: 100mg
Price: $291
Updated: 2021/12/16

ChemSupplyAustralia

Product number: 300179
Product name: 2-Cyclopropylpyridine-5-boronic acid pinacol ester, 97%
Packaging: 250mg
Price: $107.8
Updated: 2021/12/16

Synthonix

Product number: C26257
Product name: 2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
Purity: 97%
Packaging: 100mg
Price: $140
Updated: 2021/12/16

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6-CYCLOPROPYL-3-PYRIDINYL BORONIC ACID PINACOL ESTER Chemical Properties,Usage,Production

Synthesis

73183-34-3

579475-29-9

893567-09-4

A suspension was prepared in dioxane (10 mL) with 5-bromo-2-cyclopropylpyridine (0.21 g, 1.1 mmol), bis(pinacolato)diboron (0.31 g, 1.2 mmol) and potassium acetate (0.32 g, 3.2 mmol). The suspension was degassed with argon for 10 min and then PdCl2-dppf (0.026 g) was added. The reaction mixture was heated to 80 °C and kept for 15 hours. After completion of the reaction, it was cooled to room temperature and filtered through a diatomaceous earth plug. The filtrate was concentrated to give a black oily substance. The oily substance was dissolved in ether and extracted four times with 1.0 M sodium hydroxide solution. The combined yellow aqueous phases were cooled to 10°C and the pH was adjusted to 6.5 with 2.5 M hydrochloric acid, followed by repeated extraction with ether. The combined organic phases were dried with anhydrous magnesium sulfate, filtered and concentrated to give 0.27 g (103%) of 6-cyclopropylpyridine-3-boronic acid pinacol ester as a yellow oil, which solidified slowly. 1H-NMR analysis showed the product to be about 60-65% pure, with the major impurity being pinacol borane. The crude product can be directly used in the subsequent reaction without further purification.GC-MS m/z 245.2 (M+), 244.2 (M-I); 1H-NMR (CDCl3) δ 8.78 (br s, 1H), 7.93 (dd, 1H), 7.10 (d, 1H), 2.10 (m, 1H), 1.34 (s, 12H), 1.10- 1.00 (m, 4H) ppm.

References

[1] Patent: WO2006/65215, 2006, A1. Location in patent: Page/Page column 29
[2] Patent: WO2015/52264, 2015, A1. Location in patent: Paragraph 0556; 0557
[3] Patent: US2018/296543, 2018, A1. Location in patent: Page/Page column 0731; 0732

6-CYCLOPROPYL-3-PYRIDINYL BORONIC ACID PINACOL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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6-CYCLOPROPYL-3-PYRIDINYL BORONIC ACID PINACOL ESTER Suppliers

China 67 India 2 United States 6 Global 75

Shanghai Longsheng chemical Co.,Ltd.

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View Lastest Price from 6-CYCLOPROPYL-3-PYRIDINYL BORONIC ACID PINACOL ESTER manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 893567-09-4
Price: US $3.00-9.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2025-07-05

Career Henan Chemical Co

Product: 6-CYCLOPROPYL-3-PYRIDINYL BORONIC ACID PINACOL ESTER 893567-09-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg; 2kg；10kg; 100kg
Release date: 2019-08-30

893567-09-4, 6-CYCLOPROPYL-3-PYRIDINYL BORONIC ACID PINACOL ESTERRelated Search:

B-(6-Cyclopropyl-3-pyridinyl)boronic acid 2,3-CYCLOHEPTENOPYRIDINE 2-Picoline-5-boronic acid pinacolate 6-CYCLOPROPYL-3-PYRIDINYL BORONIC ACID PINACOL ESTER 6-ETHYL-3-PYRIDINYL BORONIC ACID PINACOL ESTER

6-CYCLOPROPYL-3-PYRIDINYL BORONIC ACID PINACOL ESTER

6-Cyclopropylpyridine-3-boronic acid pinacol ester

2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)

6-CYCLOPROPYL-3-PYRIDINYL BORONIC ACID PICOL ESTER

2-cyclopropyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

6-Cyclopropylpyridine-3-boronic acid pinacol ester 6-(Cyclopropyl)pyridine-3-boronic acid pinacol ester

2-Cyclopropyl-5-pyridinyl boronic acid pinacol ester

Pyridine, 2-cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine - [C26257]

893567-09-4