5-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBALDEHYDE

Product Name: 5-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBALDEHYDE
CAS No.: 878197-68-3
Chemical Name: 5-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBALDEHYDE
Synonyms: 5-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBALDEHYDE;5-bromo-Imidazo[1,2-a]pyridine-2-carboxaldehyde;Imidazo[1,2-a]pyridine-2-carboxaldehyde, 5-bromo-
CBNumber: CB82457460
Molecular Formula: C8H5BrN2O
Formula Weight: 225.04
MOL File: 878197-68-3.mol

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5-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBALDEHYDE Property

Density: 1.73±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 1.70±0.50(Predicted)
Appearance: Off-white to light yellow Solid

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AstaTech

Product number: 50617
Product name: 5-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBALDEHYDE
Purity: 95%
Packaging: 0.25G
Price: $121
Updated: 2026/04/30

AstaTech

Product number: 50617
Product name: 5-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBALDEHYDE
Purity: 95%
Packaging: 1G
Price: $303
Updated: 2026/04/30

AstaTech

Product number: 50617
Product name: 5-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBALDEHYDE
Purity: 95%
Packaging: 5G
Price: $908
Updated: 2026/04/30

Matrix Scientific

Product number: 115622
Product name: 5-Bromoimidazo[1,2-a]pyridine-2-carbaldehyde
Purity: 95+%
Packaging: 5g
Price: $1815
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0419573
Product name: 5-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBALDEHYDE
Purity: 95.00%
Packaging: 5MG
Price: $453.28
Updated: 2021/12/16

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5-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBALDEHYDE Chemical Properties,Usage,Production

Synthesis

19798-81-3

921-03-9

878197-68-3

General procedure: 2-amino-6-bromopyridine (3.0 kg, 17.3 mol) and dimethoxyethane (12 L) were added to the reactor under nitrogen protection and mixed with stirring. Subsequently, 1,1,3-trichloroacetone (5.6 kg, 30.3 mol) was added to the reaction solution at 25 °C in a single addition. The reaction system was slowly warmed to 65 °C (jacket temperature) and maintained at this temperature for 2 to 4 hours until the reaction was confirmed complete by TLC or HPLC monitoring. Upon completion of the reaction, the system was cooled to 10 °C, maintained for 1 h and filtered. The solid product was washed with dimethoxyethane (6 L). The solid was repositioned in the reactor, dimethoxyethane (12 L) and 2N hydrochloric acid (12 L) were added, and the reaction was warmed to 75 °C for 16 to 20 hours or until the reaction was complete. The reaction solution was cooled to 10 °C and the pH was adjusted to 8 with 3N sodium hydroxide solution. the solid product was collected by filtration and washed with water. Finally, the solid was dried at 50 °C for 16 h to give 5-bromoimidazo[1,2-a]pyridine-2-carbaldehyde (2.81 kg, 72% yield). The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-D6): δ 10.05 (s, 1H), 8.66 (s, 1H), 7.72 (s, 1H), 7.42 (s, 1H), 7.35 (s, 1H).

References

[1] Organic Process Research and Development, 2009, vol. 13, # 4, p. 781 - 785
[2] Patent: WO2007/87549, 2007, A2. Location in patent: Page/Page column 49
[3] Patent: WO2007/87549, 2007, A2. Location in patent: Page/Page column 39-40

5-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBALDEHYDE Suppliers

China 53 India 1 United States 5 Global 59

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878197-68-3, 5-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBALDEHYDERelated Search:

5-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID Imidazo[1,2-a]pyrazine-2-carboxylic acid, 5-bromo-, ethyl ester 5-BROMOPYRIMIDINE-2-CARBOXYLIC ACID (5-Bromopyrimidin-4-yl)methanol 5-BroMoiMidazo[1,2-a]pyridin-2-carboxylic acid Methyl ester

Imidazo[1,2-a]pyridine-2-carboxaldehyde, 5-bromo-

5-bromo-Imidazo[1,2-a]pyridine-2-carboxaldehyde

5-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBALDEHYDE

878197-68-3

978197-68-3

818797-68-3