4-CHLORO-6-METHYLNICOTINONITRILE
- Product Name
- 4-CHLORO-6-METHYLNICOTINONITRILE
- CAS No.
- 38875-76-2
- Chemical Name
- 4-CHLORO-6-METHYLNICOTINONITRILE
- Synonyms
- 4-CHLORO-6-METHYLNICOTINONITRILE;4-chloro-6-Methylpyridine-3-carbonitrile;4-Chloro-6-methyl-3-pyridinecarbonitrile;3-Pyridinecarbonitrile, 4-chloro-6-methyl-;4-CHLORO-6-METHYLNICOTINONITRILE ISO 9001：2015 REACH
- CBNumber
- CB82458124
- Molecular Formula
- C7H5ClN2
- Formula Weight
- 152.58
- MOL File
- 38875-76-2.mol
4-CHLORO-6-METHYLNICOTINONITRILE Property
- Boiling point:
- 266℃
- Density
- 1.26
- Flash point:
- 114℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C373668
- Product name
- 4-chloro-6-methylnicotinonitrile
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FC144110
- Product name
- 4-Chloro-6-methylnicotinonitrile
- Packaging
- 25mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FC144110
- Product name
- 4-Chloro-6-methylnicotinonitrile
- Packaging
- 50mg
- Price
- $125
- Updated
- 2021/12/16
- Product number
- FC144110
- Product name
- 4-Chloro-6-methylnicotinonitrile
- Packaging
- 100mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- FC144110
- Product name
- 4-Chloro-6-methylnicotinonitrile
- Packaging
- 250mg
- Price
- $350
- Updated
- 2021/12/16
4-CHLORO-6-METHYLNICOTINONITRILE Chemical Properties,Usage,Production
Synthesis
1073160-08-3
38875-76-2
Step 8. Preparation of 4-chloro-6-methylnicotinonitrile (B17-8): B17-7 (20 g, 131.5 mmol) was suspended in phosphorus trichloride (POCl3, 62 mL, 580 mmol) and heated at 110 °C for 15 minutes. After the reaction mixture was cooled to 25 °C, phosphorus pentachloride (PCl5, 38.12 g, 183.4 mmol) was added in batches over 20 min. Subsequently, the mixture was heated at 110 °C for 1 h and then concentrated. The resulting residue was diluted with ethyl acetate (EtOAc, 100 mL), cooled to 10 °C and quenched with sodium carbonate (Na2CO3, 200 mL, aqueous solution). The mixture was extracted with ethyl acetate (3 x 250 mL), the organic layers were combined, washed with brine, dried over anhydrous sodium sulfate, and concentrated. The residue was purified by silica gel column chromatography using a petroleum ether solution of 4-5% ethyl acetate as eluent to give B17-8 as an off-white fluffy solid. Yield: 7.5 g, 37%. 1H NMR (CDCl3): δ 8.75 (s, 1H), 7.38 (s, 1H), 2.65 (s, 3H). Mass spectrum: (M + 1) 153, calculated value C7H5ClN2.
References
[1] Patent: US2009/54395, 2009, A1. Location in patent: Page/Page column 44
4-CHLORO-6-METHYLNICOTINONITRILE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-CHLORO-6-METHYLNICOTINONITRILE manufacturers
- Product
- 4-CHLORO-6-METHYLNICOTINONITRILE 38875-76-2
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-26