6-tert-Butyl-2,3-naphthalenedicarbonitrile

Product Name: 6-tert-Butyl-2,3-naphthalenedicarbonitrile
CAS No.: 32703-82-5
Chemical Name: 6-tert-Butyl-2,3-naphthalenedicarbonitrile
Synonyms: 6-tert-butyl-2,3-naphthalonitrile;LABOTEST-BB LT00159322;BRD9876, 10 mM in DMSO;6-tert-Butyl-2,3-naphthalodinitrile;6-tert-Butyl-2,3-dicyanonaphthalene;2,3-Dicyano-6-tert-butylnaphthalene;6-TERT-BUTYL-2,3-NAPHTHALENEDICARBONITRILE;6-tert-Butyl-2,3-naphthalenedicarbonitrile;6-(1,1-Dimethylethyl)-2,3-naphthalenedicarbonitrile;2,3-NAPHTHALENEDICARBONITRILE, 6-(1,1-DIMETHYLETHYL)-
CBNumber: CB8246053
Molecular Formula: C16H14N2
Formula Weight: 234.3
MOL File: 32703-82-5.mol

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6-tert-Butyl-2,3-naphthalenedicarbonitrile Property

Melting point:: 185-189 °C(lit.)
Boiling point:: 429.7±33.0 °C(Predicted)
Density: 1.11±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly)
form: Solid
color: Pale Yellow to Light Beige
InChI: InChI=1S/C16H14N2/c1-16(2,3)15-5-4-11-6-13(9-17)14(10-18)7-12(11)8-15/h4-8H,1-3H3
InChIKey: MKILROQBJOOZKC-UHFFFAOYSA-N
SMILES: C1=C2C(C=C(C(C)(C)C)C=C2)=CC(C#N)=C1C#N

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22
Safety Statements: 36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 425265
Product name: 6-tert-Butyl-2,3-naphthalenedicarbonitrile
Purity: 94%
Packaging: 1g
Price: $94.9
Updated: 2023/01/07

TRC

Product number: B694158
Product name: 6-tert-Butyl-2,3-naphthalenedicarbonitrile
Packaging: 2.5g
Price: $125
Updated: 2021/12/16

Chem-Impex

Product number: 41882
Product name: 6-tert-Butyl-2,3-naphthalenedicarbonitrile,≥93%(HPLC),suitableforHematology&Histology
Purity: ≥93%(HPLC)
Packaging: 1G
Price: $81.54
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB140669
Product name: 6-(tert-Butyl)naphthalene-2,3-dicarbonitrile
Packaging: 250mg
Price: $97.5
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB140669
Product name: 6-(tert-Butyl)naphthalene-2,3-dicarbonitrile
Packaging: 500mg
Price: $170
Updated: 2021/12/16

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6-tert-Butyl-2,3-naphthalenedicarbonitrile Chemical Properties,Usage,Production

Uses

6-tert-Butyl-2,3-naphthalenedicarbonitrile is a stain with bioloigcal research applications. Dyes and metabolites.

Definition

ChEBI: 6-tert-butylnaphthalene-2,3-dicarbonitrile is a member of naphthalenes.

Biological Activity

BRD9876 is an inhibitor of the kinesin spindle protein Eg5. It arrests Eg5-mediated microtubule gliding, as well as inhibits Eg5 ATPase activity in the presence of microtubules, in cell-free assays. BRD9876 is cytotoxic to MM.1S stroma-independent multiple myeloma cells (IC50 = 2.2 μM). It induces cell cycle arrest at the G2/M phase in MM.1S cells when used at a concentration of 10 μM.

References

[1] SHRIKANTA CHATTOPADHYAY. Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors.[J]. Cell reports, 2015, 10 5: 755-770. DOI: 10.1016/j.celrep.2015.01.017

6-tert-Butyl-2,3-naphthalenedicarbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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6-tert-Butyl-2,3-naphthalenedicarbonitrile Suppliers

China 48 Germany 1 India 1 Switzerland 2 United Kingdom 3 United States 9 Global 64

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Energy Chemical

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BOC Sciences

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Shanghai EFE Biological Technology Co., Ltd.

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Shanghai YuanYe Biotechnology Co., Ltd.

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View Lastest Price from 6-tert-Butyl-2,3-naphthalenedicarbonitrile manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 6-tert-Butyl-2,3-naphthalenedicarbonitrile 32703-82-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2024-08-01

32703-82-5, 6-tert-Butyl-2,3-naphthalenedicarbonitrileRelated Search:

2-ETHYL-6-METHYLNAPHTHALENE Phthalonitrile 2,3,6-TRIMETHYLNAPHTHALENE 1,4-Pentadien-3-ol 2,7-DIMETHYLNAPHTHALENE 2-Naphthonitrile 6-tert-Butyl-2,3-naphthalenedicarbonitrile 3,3,6,6-Tetramethoxy-1,4-cyclohexadiene 2,3-Dicyanonaphthalene 2-tert-butylnaphthalene 2,6-DIMETHYLNAPHTHALENE

LABOTEST-BB LT00159322

6-TERT-BUTYL-2,3-NAPHTHALENEDICARBONITRILE

2,3-Dicyano-6-tert-butylnaphthalene

6-tert-Butyl-2,3-dicyanonaphthalene

6-tert-Butyl-2,3-naphthalodinitrile

2,3-NAPHTHALENEDICARBONITRILE, 6-(1,1-DIMETHYLETHYL)-

6-(1,1-Dimethylethyl)-2,3-naphthalenedicarbonitrile

6-tert-butyl-2,3-naphthalonitrile

Kinesin,microtubule,Inhibitor,BRD9876,BMSC,multiple,myeloma,α4-α6,CD34,tyrosine,ATP,MM1S,G2/M,BRD-9876,mitotic,BRD 9876,Microtubule/Tubulin,inhibit

BRD9876, 10 mM in DMSO

6-<i>tert</i>-Butyl-2,3-naphthalenedicarbonitrile

32703-82-5

CH33CC10H5CN2

B

Stains and Dyes

Stains&Dyes, A to