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FURO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID

Product Name
FURO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID
CAS No.
112372-15-3
Chemical Name
FURO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID
Synonyms
FURO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID;Furo[2,3-c]pyridine-2-Carbocylic acid;Furo[2,3-c]pyridine-2-carboxylic acid (9CI, ACI);2-Carboxyfuro[2,3-c]pyridine, 2-Carboxy-6-azabenzo[b]furan
CBNumber
CB82465797
Molecular Formula
C8H5NO3
Formula Weight
163.13
MOL File
112372-15-3.mol
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FURO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID Property

Melting point:
>320℃
Boiling point:
353.0±22.0 °C(Predicted)
Density 
1.455
storage temp. 
2-8°C
pka
1.95±0.30(Predicted)
Appearance
White to off-white Solid
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0006616
Product name
Furo[2,3-c]pyridine-2-carboxylicacid
Purity
99.95%
Packaging
100mg
Price
$129
Updated
2021/12/16
ChemScene
Product number
CS-0006616
Product name
Furo[2,3-c]pyridine-2-carboxylicacid
Purity
99.95%
Packaging
250mg
Price
$195
Updated
2021/12/16
Matrix Scientific
Product number
101660
Product name
Furo[2,3-c]pyridine-2-carboxylic acid
Purity
98%
Packaging
250mg
Price
$215
Updated
2021/12/16
AK Scientific
Product number
8940AC
Product name
Furo[2,3-c]pyridine-2-carboxylicacid
Packaging
250mg
Price
$311
Updated
2021/12/16
Matrix Scientific
Product number
101660
Product name
Furo[2,3-c]pyridine-2-carboxylic acid
Purity
98%
Packaging
500mg
Price
$351
Updated
2021/12/16
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FURO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID Chemical Properties,Usage,Production

Synthesis

138173-83-8

112372-15-3

General procedure for the synthesis of furo[2,3-c]pyridine-2-carboxylic acid from ethyl furo[2,3-c]pyridine-2-carboxylate: ethyl furo[2,3-c]pyridine-2-carboxylate (3.82 g, 19.98 mmol) was dissolved in a mixed solvent of THF:MeOH (1:1, 6.4 mL) and potassium hydroxide (3.36 g, 59.9 mmol). The reaction mixture was stirred at room temperature for 16 hours. Upon completion of the reaction, the solvent was concentrated under reduced pressure to about 20 mL and the pH was subsequently adjusted with acetic acid to about 4. The precipitated solid product was collected by vacuum filtration, washed twice with water, and dried overnight in a vacuum oven to afford furano[2,3-c]pyridine-2-carboxylic acid (2.90 g, 89% yield). The product was characterized by 1H NMR (DMSO-d6): δ 9.09 (s, 1H), 8.47 (d, 1H), 7.81 (dd, 1H), 7.71 (d, 1H), 3.36 (br s, 1H).

References

[1] Patent: WO2012/31197, 2012, A1. Location in patent: Page/Page column 400-401
[2] Patent: WO2013/127266, 2013, A1. Location in patent: Page/Page column 128; 129; 130
[3] Patent: WO2013/127267, 2013, A1. Location in patent: Page/Page column 79; 81
[4] Patent: WO2013/127269, 2013, A1. Location in patent: Page/Page column 143
[5] Patent: WO2013/127268, 2013, A1. Location in patent: Page/Page column 57; 59

FURO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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FURO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID Suppliers

China 48 India 1 United Kingdom 2 United States 4 Global 55
Apollo Scientific Ltd.
Tel
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Fax
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Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
Fluorochem Ltd.
Tel
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Fax
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Email
enquiries@fluorochem.co.uk
Country
United Kingdom
ProdList
6401
Advantage
74

112372-15-3, FURO[2,3-C]PYRIDINE-2-CARBOXYLIC ACIDRelated Search:

Furo[2,3-b]pyridin-3(2H)-one ethyl furo[2,3-c]pyridine-2-carboxylate Furo[2,3-c]pyridin-3(2H)-one (9CI) furo[2,3-c]pyridin-7-amine Furo[3,2-b]pyridine-2-carboxaldehyde (9CI)

  • Furo[2,3-c]pyridine-2-Carbocylic acid
  • FURO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID
  • 2-Carboxyfuro[2,3-c]pyridine, 2-Carboxy-6-azabenzo[b]furan
  • Furo[2,3-c]pyridine-2-carboxylic acid (9CI, ACI)
  • 112372-15-3