tert-butyl 4-(aminomethyl)-4-methylpiperidine-1-carboxylate
Application- Product Name
- tert-butyl 4-(aminomethyl)-4-methylpiperidine-1-carboxylate
- CAS No.
- 236406-22-7
- Chemical Name
- tert-butyl 4-(aminomethyl)-4-methylpiperidine-1-carboxylate
- Synonyms
- 4-AMinoMethyl-1-Boc-4-Met...;4-aMinoMethyl-1-t-butoxycarbony;4-AMinoMethyl-1-Boc-4-Methylpiperidine;1-Boc-4-(aMinoMethyl)-4-Methylpiperidine;1-Boc-4-methyl-4-(aminomethyl)-piperidine;4-aMinoMethyl-1-t-butoxycarbonyl-4-Methylpiperidine;tert-butyl 4-(aminomethyl)-4-methylpiperidine-1-carboxylate;1-Piperidinecarboxylic acid, 4-(aminomethyl)-4-methyl-, 1,1-dimethylethyl ester
- CBNumber
- CB82470391
- Molecular Formula
- C12H24N2O2
- Formula Weight
- 228.33
- MOL File
- 236406-22-7.mol
tert-butyl 4-(aminomethyl)-4-methylpiperidine-1-carboxylate Property
- Density
- 1.002
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- Appearance
- gray liquid
Safety
- RIDADR
- UN2811
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B750945
- Product name
- tert-Butyl4-(Aminomethyl)-4-methylpiperidine-1-carboxylate
- Packaging
- 100mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- B750945
- Product name
- tert-Butyl4-(Aminomethyl)-4-methylpiperidine-1-carboxylate
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FB144086
- Product name
- tert-Butyl 4-(aminomethyl)-4-methylpiperidine-1-carboxylate
- Packaging
- 100mg
- Price
- $56
- Updated
- 2021/12/16
- Product number
- FB144086
- Product name
- tert-Butyl 4-(aminomethyl)-4-methylpiperidine-1-carboxylate
- Packaging
- 1g
- Price
- $340
- Updated
- 2021/12/16
- Product number
- 4H56-1-023
- Product name
- 4-Aminomethyl-1-Boc-4-methylpiperidine
- Packaging
- 1g
- Price
- $525
- Updated
- 2021/12/16
tert-butyl 4-(aminomethyl)-4-methylpiperidine-1-carboxylate Chemical Properties,Usage,Production
Application
4-(aminomethyl)-4-methylpiperidine-1-carboxylic acid tert-butyl ester is an ester derivative that can be used as an organic reagent.
Synthesis
530115-96-9
236406-22-7
General procedure for the synthesis of tert-butyl 4-(aminomethyl)-4-methylpiperidine-1-carboxylate from tert-butyl 4-cyano-4-methylpiperidine-1-carboxylate: Compound 25 (1.00 g, 4.46 mmol) was reacted with Rh/Al2O3 catalyst (300 mg, 5 wt%, 0.14 mmol) in a methanol-ammonia solution under hydrogen atmosphere (40 psi) ( 15 mL, 3.5 N NH3 in MeOH) was subjected to a shaking reaction. After completion of the reaction, the reaction mixture was filtered through a silica gel pad and the filtrate was concentrated to give the target product compound 26 (1.00 g, 98% yield).
References
[1] Patent: US2004/10013, 2004, A1. Location in patent: Page/Page column 51
[2] Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 2, p. 608 - 611
[3] Patent: WO2016/77375, 2016, A1. Location in patent: Page/Page column 151
tert-butyl 4-(aminomethyl)-4-methylpiperidine-1-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from tert-butyl 4-(aminomethyl)-4-methylpiperidine-1-carboxylate manufacturers
- Product
- tert-butyl 4-(aminomethyl)-4-methylpiperidine-1-carboxylate 236406-22-7
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg,5kg,50kg
- Release date
- 2020-01-18