1,4-Dichloro-5,6,7,8-tetrahydrophthalazine
- Product Name
- 1,4-Dichloro-5,6,7,8-tetrahydrophthalazine
- CAS No.
- 67279-24-7
- Chemical Name
- 1,4-Dichloro-5,6,7,8-tetrahydrophthalazine
- Synonyms
- 1,4-Dichloro-5,6,7,8-tetrahydrophthalazine;Phthalazine, 1,4-dichloro-5,6,7,8-tetrahydro-
- CBNumber
- CB82471590
- Molecular Formula
- C8H8Cl2N2
- Formula Weight
- 203.07
- MOL File
- 67279-24-7.mol
1,4-Dichloro-5,6,7,8-tetrahydrophthalazine Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Appearance
- Off-white to light yellow Solid
N-Bromosuccinimide Price
- Product number
- HCH0317935
- Product name
- 1,4-DICHLORO-5,6,7,8-TETRAHYDROPHTHALAZINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.29
- Updated
- 2021/12/16
- Product number
- 9295CT
- Product name
- 1,4-Dichloro-5,6,7,8-tetrahydrophthalazine
- Packaging
- 1g
- Price
- $548
- Updated
- 2021/12/16
- Product number
- 161961
- Product name
- 1,4-Dichloro-5,6,7,8-tetrahydrophthalazine
- Purity
- 95%
- Packaging
- 5g
- Price
- $1050
- Updated
- 2021/12/16
- Product number
- 161961
- Product name
- 1,4-Dichloro-5,6,7,8-tetrahydrophthalazine
- Purity
- 95%
- Packaging
- 10g
- Price
- $1750
- Updated
- 2021/12/16
- Product number
- A117671
- Product name
- 1,4-Dichloro-5,6,7,8-tetrahydrophthalazine
- Purity
- 97%
- Packaging
- 100mg
- Price
- $88
- Updated
- 2021/12/16
1,4-Dichloro-5,6,7,8-tetrahydrophthalazine Chemical Properties,Usage,Production
Chemical Properties
White solid
Uses
1,4-Dichloro-5,6,7,8-tetrahydronaphthalene can be used in organic synthesis and pharmaceutical intermediates.
Synthesis
67279-23-6
67279-24-7
2,3,5,6,7,8-Hexahydrophthalazine-1,4-dione (40) (2.09 g, 12.6 mmol) was used as a starting material, which was suspended in phosphorus trichloride (POCl3, 10 mL) and heated to reflux for 1 hour. After completion of the reaction, it was cooled to room temperature and the reaction mixture was slowly poured into ice water. The precipitated solid product was collected by filtration and dried in a vacuum oven to afford 1,4-dichloro-5,6,7,8-tetrahydro-2,3-diazanaphthalene (41) (2.23 g, 87% yield). The molecular ion peak (MH+) was determined as 203.0139 by high resolution mass spectrometry (HR MS).
References
[1] Patent: US2010/41663, 2010, A1. Location in patent: Page/Page column 42
[2] Patent: WO2008/110611, 2008, A1. Location in patent: Page/Page column 104
[3] Patent: WO2011/80510, 2011, A1. Location in patent: Page/Page column 71
[4] Journal of Organic Chemistry, 1955, vol. 20, p. 707,708
[5] Journal of Medicinal Chemistry, 2004, vol. 47, # 14, p. 3642 - 3657
1,4-Dichloro-5,6,7,8-tetrahydrophthalazine Preparation Products And Raw materials
Raw materials
Preparation Products
1,4-Dichloro-5,6,7,8-tetrahydrophthalazine Suppliers
- Tel
- --
- Fax
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- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
View Lastest Price from 1,4-Dichloro-5,6,7,8-tetrahydrophthalazine manufacturers
- Product
- 1,4-Dichloro-5,6,7,8-tetrahydrophthalazine 67279-24-7
- Price
- US $0.00/KG
- Min. Order
- 1g
- Purity
- 98%minNMR
- Supply Ability
- 10kgs/month
- Release date
- 2021-12-28