ChemicalBook > CAS DataBase List > Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2R)-

Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2R)-

Product Name
Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2R)-
CAS No.
908303-26-4
Chemical Name
Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2R)-
Synonyms
(2R)-2-{bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)...;(R)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]prolinol trimethylsilyl ether;R-2-[bis[3,5-bis(trifluoroMethyl)phenyl][(triMethyl silyl)oxy]Methyl]-Pyrrolidine;(2R)-2-[Bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]pyrrolidine;(R)-2-[(Bis(3,5-bis(trifluoroMethyl)phenyl)]triMethylsilanyloxy)Methyl]pyrrolidine;[bis[3,5-bis(trifluoromethyl)phenyl]-[(2R)-pyrrolidin-2-yl]methoxy]-trimethylsilane;(R)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol trimethylsilyl ether;Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2R)-;(R)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]prolinol trimethylsilyl ether, CAS 908303-26-4;(2R)-2-[Bis[3,5-bis(trifluoromethyl)phenyl]- [(trimethylsilyl)oxy]methyl]pyrrolidine,99%e.e.
CBNumber
CB82473721
Molecular Formula
C24H23F12NOSi
Formula Weight
597.51
MOL File
908303-26-4.mol
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Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2R)- Property

Melting point:
46-55°C
Boiling point:
382.4±37.0 °C(Predicted)
Density 
1.319±0.06 g/cm3(Predicted)
Flash point:
>110℃
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
form 
Solid
pka
9.34±0.10(Predicted)
color 
White to Off-White
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
677213
Product name
(R)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol trimethylsilyl ether
Purity
technical grade
Packaging
5g
Price
$394.5
Updated
2025/07/31
Sigma-Aldrich
Product number
677213
Product name
(R)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol trimethylsilyl ether
Purity
technical grade
Packaging
1g
Price
$536
Updated
2025/07/31
TRC
Product number
B412955
Product name
(2R)-2-[Bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-pyrrolidine
Packaging
1g
Price
$130
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB100936
Product name
(2R)-2-[Bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]pyrrolidine
Packaging
100mg
Price
$55
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB100936
Product name
(2R)-2-[Bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]pyrrolidine
Packaging
250mg
Price
$85
Updated
2021/12/16
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Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2R)- Chemical Properties,Usage,Production

Uses

Catalyst involved in:

  • Cyclocondensation of enals with methylenepyrrolidines
  • Organocatalytic additions of β-ketosulfoxides to conjugated aldehydes
  • Organocatalytic aza-Michael reactions
  • Stereoselective propargylic alkylation of propargylic esters with aldehydes
  • Epoxidation or aziridination of α,β-unsaturated aldehydes and Feist-Benary reactions of 1,3-dicarbonyls

Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2R)- Preparation Products And Raw materials

Raw materials

Preparation Products

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Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2R)- Suppliers

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908303-26-4, Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2R)-Related Search:


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