3-Methoxy-4-(trifluoromethyl)phenylamine
- Product Name
- 3-Methoxy-4-(trifluoromethyl)phenylamine
- CAS No.
- 106877-20-7
- Chemical Name
- 3-Methoxy-4-(trifluoromethyl)phenylamine
- Synonyms
- 3-Methoxy-4-(trifluoromethyl);3-Methoxy-4-(trifluoromethyl)phenylamine;3-Methoxy-4-(trifluoromethyl)benzenamine;Benzenamine, 3-methoxy-4-(trifluoromethyl)-
- CBNumber
- CB82478852
- Molecular Formula
- C8H8F3NO
- Formula Weight
- 191.15
- MOL File
- 106877-20-7.mol
3-Methoxy-4-(trifluoromethyl)phenylamine Property
- Melting point:
- 49-50°
- storage temp.
- -20°C, sealed storage, away from moisture
- Appearance
- Light yellow to yellow Solid
Safety
- HazardClass
- IRRITANT
- HS Code
- 2922190090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M269465
- Product name
- 3-Methoxy-4-(trifluoromethyl)aniline
- Packaging
- 500mg
- Price
- $175
- Updated
- 2021/12/16
- Product number
- 046260
- Product name
- 3-Methoxy-4-(trifluoromethyl)phenylamine
- Purity
- >95%
- Packaging
- 1g
- Price
- $230
- Updated
- 2021/12/16
- Product number
- HCH0365073
- Product name
- 3-METHOXY-4-(TRIFLUOROMETHYL)ANILINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.35
- Updated
- 2021/12/16
- Product number
- 046260
- Product name
- 3-Methoxy-4-(trifluoromethyl)phenylamine
- Purity
- >95%
- Packaging
- 5g
- Price
- $600
- Updated
- 2021/12/16
- Product number
- PC201016
- Product name
- 3-Methoxy-4-(trifluoromethyl)aniline
- Packaging
- 1g
- Price
- $115
- Updated
- 2021/12/16
3-Methoxy-4-(trifluoromethyl)phenylamine Chemical Properties,Usage,Production
Synthesis
453560-74-2
106877-20-7
General procedure for the synthesis of 3-methoxy-4-(trifluoromethyl)aniline from 2-methoxy-4-nitro-1-(trifluoromethyl)benzene: Intermediate 444 (7.1 g, 28.9 mmol) was dissolved in methanol (100 mL) followed by addition of 5% Pd/C catalyst (0.7 g). The reaction mixture was hydrogenated under hydrogen atmosphere (50 Psi) for 48 hours at room temperature. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to give Intermediate 445 (7 g) as a white solid.
References
[1] Journal of Medicinal Chemistry, 2014, vol. 57, # 5, p. 1914 - 1931
[2] Patent: US2010/311760, 2010, A1. Location in patent: Page/Page column 42-43
[3] Patent: WO2017/32840, 2017, A1. Location in patent: Page/Page column 226
3-Methoxy-4-(trifluoromethyl)phenylamine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Methoxy-4-(trifluoromethyl)phenylamine manufacturers
- Product
- 3-Methoxy-4-(trifluoromethyl)phenylamine 106877-20-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 97%
- Supply Ability
- 200kg
- Release date
- 2020-02-01