2-Chloro-4-ethoxy-6-methyl-pyrimidine

Product Name: 2-Chloro-4-ethoxy-6-methyl-pyrimidine
CAS No.: 37482-64-7
Chemical Name: 2-Chloro-4-ethoxy-6-methyl-pyrimidine
Synonyms: 2-Chloro-4-ethoxy-6-methyl-pyrimidine;Pyrimidine, 2-chloro-4-ethoxy-6-methyl-;2-chloro-4-ethoxy-6-methyl-pyrimidine - [C86616];2-Chloro-4-ethoxy-6-methyl-pyrimidine ISO 9001：2015 REACH
CBNumber: CB82483739
Molecular Formula: C7H9ClN2O
Formula Weight: 172.61
MOL File: 37482-64-7.mol

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2-Chloro-4-ethoxy-6-methyl-pyrimidine Property

Melting point:: 70-73℃
Boiling point:: 282℃
Density: 1.193
Flash point:: 124℃
storage temp.: Storage temp. 2-8°C
pka: 0.76±0.30(Predicted)
Appearance: White to off-white Solid

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Safety

HazardClass: IRRITANT
HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Matrix Scientific

Product number: 034263
Product name: 2-Chloro-4-ethoxy-6-methyl-pyrimidine
Purity: 95+%
Packaging: 1g
Price: $150
Updated: 2021/12/16

Apolloscientific

Product number: OR949617
Product name: 2-Chloro-4-ethoxy-6-methyl-pyrimidine
Purity: 95%
Packaging: 250mg
Price: $180
Updated: 2021/12/16

Apolloscientific

Product number: OR949617
Product name: 2-Chloro-4-ethoxy-6-methyl-pyrimidine
Purity: 95%
Packaging: 1g
Price: $360
Updated: 2021/12/16

Matrix Scientific

Product number: 034263
Product name: 2-Chloro-4-ethoxy-6-methyl-pyrimidine
Purity: 95+%
Packaging: 5g
Price: $525
Updated: 2021/12/16

AK Scientific

Product number: 4795AB
Product name: 2-Chloro-4-ethoxy-6-methylpyrimidine
Packaging: 5g
Price: $758
Updated: 2021/12/16

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2-Chloro-4-ethoxy-6-methyl-pyrimidine Chemical Properties,Usage,Production

Uses

2-Chloro-4-ethoxy-6-methylpyrimidine is a reactant/starting material in the preparation of azolylpyrimidines as cytoprotective antiulcer agents.

Synthesis

5424-21-5

64-17-5

37482-64-7

General procedure: 2,4-dichloro-6-methylpyrimidine (3.0 g, 18.4 mmol), cesium carbonate (Cs2CO3, 6.6 g, 20.2 mmol) and ethanol (EtOH, 46 mL) were added to a reaction flask, and the mixture was stirred under reflux conditions for 48 hours. After completion of the reaction, the solid insoluble material was removed by filtration and the filtrate was purified by column chromatography to afford the target product 2-chloro-4-ethoxy-6-methylpyrimidine (1.88 g, 59% yield). The structure of the product was confirmed by 1H-NMR (CDCl3): δ6.47 (1H, s), 4.41 (2H, q), 2.42 (3H, s), 1.39 (3H, t).

References

[1] Patent: EP3239143, 2017, A2. Location in patent: Paragraph 0476
[2] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 21, p. 5206 - 5220
[3] Patent: WO2016/133959, 2016, A1. Location in patent: Page/Page column 46; 47

2-Chloro-4-ethoxy-6-methyl-pyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Chloro-4-ethoxy-6-methyl-pyrimidine Suppliers

China 32 United Kingdom 1 United States 3 Global 36

Shanghai Boyle Chemical Co., Ltd.

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View Lastest Price from 2-Chloro-4-ethoxy-6-methyl-pyrimidine manufacturers

Dideu Industries Group Limited

Product: 2-Chloro-4-ethoxy-6-methyl-pyrimidine 37482-64-7
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-07

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2-Chloro-4-ethoxy-6-methyl-pyrimidine

2-Chloro-4-ethoxy-6-methyl-pyrimidine ISO 9001：2015 REACH

Pyrimidine, 2-chloro-4-ethoxy-6-methyl-

2-chloro-4-ethoxy-6-methyl-pyrimidine - [C86616]

37482-64-7