2,4-Dichloro-5-(chloromethyl)pyrimidine Property

Melting point:

63-64°

Boiling point:

90-100 °C(Press: 0.001 Torr)

Density 

1.548±0.06 g/cm3(Predicted)

pka

-3.42±0.29(Predicted)

form 

Solid

color 

White to cream

Safety

HazardClass 

IRRITANT

HS Code 

2933599590

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H318Causes serious eye damage

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P501Dispose of contents/container to..…

2,4-Dichloro-5-(chloromethyl)pyrimidine Chemical Properties,Usage,Production

Uses

2,4-Dichloro-5-(chloromethyl)pyrimidine is an intermediate; used in preparation of fused pyrimidine compounds for the treatment of cancers associated with EGFR and HER2 mutations.