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5-pyrimidineethanol

Product Name
5-pyrimidineethanol
CAS No.
875251-47-1
Chemical Name
5-pyrimidineethanol
Synonyms
2-(Pyrimidin-5-yl);5-pyrimidineethanol;2-(pyriMidin-5-yl)ethanol;2-(pyriMidin-5-yl)ethan-1-ol;5-pyrimidineethanol ISO 9001：2015 REACH
CBNumber
CB82484529
Molecular Formula
C6H8N2O
Formula Weight
124.14
MOL File
875251-47-1.mol
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5-pyrimidineethanol Property

Boiling point:
252℃
Density 
1.168
Flash point:
106℃
storage temp. 
Sealed in dry,Room Temperature
pka
14.50±0.10(Predicted)
Appearance
Off-white to light yellow Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B526268
Product name
2-(pyrimidin-5-yl)ethanol
Packaging
25mg
Price
$155
Updated
2021/12/16
AK Scientific
Product number
W8980
Product name
5-Pyrimidineethanol
Packaging
250mg
Price
$477
Updated
2021/12/16
Matrix Scientific
Product number
089773
Product name
2-(Pyrimidin-5-yl)ethanol
Purity
95+%
Packaging
250mg
Price
$515
Updated
2021/12/16
Matrix Scientific
Product number
089773
Product name
2-(Pyrimidin-5-yl)ethanol
Purity
95+%
Packaging
1g
Price
$1143
Updated
2021/12/16
Crysdot
Product number
CD11038296
Product name
2-(Pyrimidin-5-yl)ethanol
Purity
98%
Packaging
250mg
Price
$248
Updated
2021/12/16
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5-pyrimidineethanol Chemical Properties,Usage,Production

Synthesis

6214-48-8

875251-47-1

Ethyl 2-(pyrimidin-5-yl)acetate (200 mg, 1.20 mmol) was dissolved in ethanol (15 mL) under argon protection and stirred at 0 °C. Sodium borohydride (91 mg, 2.40 mmol) was slowly added, followed by warming the reaction system to room temperature and continuous stirring for 16 hours. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction was quenched with ice water (2 mL), followed by removal of the volatile solvent under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography with an eluent of 4% methanol/dichloromethane (v/v) to afford 2-(pyrimidin-5-yl)ethanol (45 mg, 30% yield) as a colorless slurry. The product was confirmed by 1H-NMR (DMSO-d6, 500 MHz): δ 9.01 (s, 1H), 8.62 (s, 2H), 4.76 (t, 1H), 3.66-3.64 (m, 2H), 2.78-2.76 (t, 2H).The LC-MS analysis showed a purity of 98.71% with a molecular ion peak of 125 (M++1). The chromatographic conditions: the column was Eclipse XDB C-18 (150×4.6 mm, 5 μm), the mobile phase was 0.05% aqueous trifluoroacetic acid: acetonitrile at a flow rate of 1.0 mL/min, and the retention time was 3.75 min. The purity of UPLC analysis was 96.67%, and the chromatographic conditions: the column was Acquity UPLC HSS T3 (2.1×100 mm. 1.8 μm), mobile phase: acetonitrile: 0.025% trifluoroacetic acid aqueous solution, flow rate 0.3 mL/min, retention time 1.86 min (IP12060040).TLC conditions: 10% methanol/dichloromethane (v/v), Rf value was 0.4. The purity of UPLC analysis was 96.67%.

References

[1] Patent: WO2013/142269, 2013, A1. Location in patent: Paragraph 0712; 0713; 0714

5-pyrimidineethanol Preparation Products And Raw materials

Raw materials

Preparation Products

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5-pyrimidineethanol Suppliers

Austria 1 China 44 France 1 Germany 2 India 1 Ukraine 1 United States 5 Global 55
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Proactive Molecular Research
Tel
--
Fax
--
Email
tony@proactivemr.com
Country
United States
ProdList
895
Advantage
0
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View Lastest Price from 5-pyrimidineethanol manufacturers

Dideu Industries Group Limited
Product
5-pyrimidineethanol 875251-47-1
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons
Release date
2022-02-16
Career Henan Chemical Co
Product
5-pyrimidineethanol 875251-47-1
Price
US $2.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
ask
Release date
2019-12-24

875251-47-1, 5-pyrimidineethanolRelated Search:


  • 5-pyrimidineethanol
  • 2-(pyriMidin-5-yl)ethan-1-ol
  • 2-(pyriMidin-5-yl)ethanol
  • 2-(Pyrimidin-5-yl)
  • 5-pyrimidineethanol ISO 9001：2015 REACH
  • 875251-47-1
  • Heterocycle-Pyrimidine series