ChemicalBook > CAS DataBase List > N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide

N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide

Product Name: N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide
CAS No.: 918505-61-0
Chemical Name: N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide
Synonyms: CS-1029;PLX 4032;INXN-1001;ZELBORAF.(R).;BRAF inhibitor;PLX-4032(RG7204);Vemurafenib-Analog;BRAF inhibitor, 10 mM in DMSO;BRAF inhibitor (Compound P-0850);Raf kinases,inhibit,Inhibitor,BRAF inhibitor,Raf
CBNumber: CB82489948
Molecular Formula: C22H18F2N4O3S
Formula Weight: 456.47
MOL File: 918505-61-0.mol

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N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide Property

Density: 1.45
storage temp.: Store at -20°C
solubility: DMSO : 50 mg/mL (109.54 mM; Need ultrasonic)
form: Powder
pka: 6.54±0.10(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FV15248
Product name: PLX 4032
Packaging: 50mg
Price: $75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FV15248
Product name: PLX 4032
Packaging: 100mg
Price: $100
Updated: 2021/12/16

ChemScene

Product number: CS-0055
Product name: BRAFinhibitor
Purity: 98.61%
Packaging: 10mg
Price: $180
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FV15248
Product name: PLX 4032
Packaging: 250mg
Price: $187.5
Updated: 2021/12/16

ApexBio Technology

Product number: A3263
Product name: BRAFinhibitor
Packaging: 10mg
Price: $293
Updated: 2021/12/16

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N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide Chemical Properties,Usage,Production

Uses

Vemurafenib selective BRAFV600E kinase inhibitor; an antitumor agent. Vemurafenib functions by inhibiting the proliferation and mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressing BRAFV600E or other mutant BRAF proteins altered at codon 600. Potent B-Raf inhibitor

N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide manufacturers

Career Henan Chemical Co

Product: N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide 918505-61-0
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-08

918505-61-0, N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamideRelated Search:

PLX-4032(RG7204)

N-(2,4-Difluoro-3-(5-(pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)phenyl)propane-2-sulfinamide

PLX 4032

BRAF inhibitor

ZELBORAF.(R).

2-PropanesulfonaMide, N-[2,4-difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-

N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide

N-(2,4-Difluoro-3-(5-(pyridin-3-yl)-1H-pyrrolo[2,3-b]-pyridine-3-carbonyl)phenyl)propane-2-sulfin

N-(2,4-Difluoro-3-(5-(pyridin-3-yl)-1H-pyrrolo[2,3-b]-pyridine-3-carbonyl)phenyl)propane-2-sul

N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]-2-propanesulfonamide

CS-1029

Vemurafenib-Analog

N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin...

INXN-1001

Raf kinases,inhibit,Inhibitor,BRAF inhibitor,Raf

BRAF inhibitor, 10 mM in DMSO

BRAF inhibitor (Compound P-0850)

N-(2,4-difluoro-3-(5-(pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)phenyl)propane-2-sulfonamide

918505-61-0

C22H18F2N4O3S