VCH-916

Product Name: VCH-916
CAS No.: 1200133-34-1
Chemical Name: VCH-916
Synonyms: CS-790;VCH-916;VCH-916, >=98%;VCH 916;VCH916;VCH-916 (Free);HCV,VCH 916,VCH916,Hepatitis C virus,VCH-916,inhibit,Inhibitor;potassiuM 5-cyclohexenyl-3-(N-((1r,4r)-4-Methoxycyclohexyl)-4-MethylcyclohexanecarboxaMido)thiophene-2-carboxylate;Potassium 5-(cyclohex-1-en-1-yl)-3-(trans-N-(trans-4-methoxycyclohexyl)-4-methylcyclohexane-1-carboxamido)thiophene-2-carboxylate;5-(1-Cyclohexen-1-yl)-3-[(trans-4-methoxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino]-2-thiophenecarboxylic acid potassium salt
CBNumber: CB82504463
Molecular Formula: C26H36KNO4S
Formula Weight: 497.73164
MOL File: 1200133-34-1.mol

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VCH-916 Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Powder
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-1224
Product name: VCH-916
Purity: 99.51%
Packaging: 5mg
Price: $180
Updated: 2021/12/16

ApexBio Technology

Product number: A3909
Product name: VCH-916
Packaging: 2mg
Price: $189
Updated: 2021/12/16

ChemScene

Product number: CS-1224
Product name: VCH-916
Purity: 99.51%
Packaging: 10mg
Price: $200
Updated: 2021/12/16

ApexBio Technology

Product number: A3909
Product name: VCH-916
Packaging: 5mg
Price: $308
Updated: 2021/12/16

ApexBio Technology

Product number: A3909
Product name: VCH-916
Packaging: 10mg
Price: $410
Updated: 2021/12/16

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VCH-916 Chemical Properties,Usage,Production

Uses

VCH-916 is a novel nonnucleoside HCV NS5B polymerase inhibitor. IC50 Value: Target: HCV VCH-916 is a novel allosteric inhibitor of HCV NS5B polymerase. The RNA-dependent RNA polymerase (NS5B) of HCV is one of the attractive validated targets for development of new drugs to block HCV infection. VCH-916 is currently being evaluated for safety/tolerability, pharmacokinetics and anti-viral efficacy in chronically infected HCV patient.

References

[1] Ludmila Gerber, Tania M. Welzel, Stefan Zeuzem. New therapeutic strategies in HCV: polymerase inhibitors. Liver International. 2013,33(s1): 85-92
[2] Abdelrahman S. Mayhoub. Hepatitis C RNA-dependent RNA polymerase inhibitors: A review of structure-activity and resistance relationships; different scaffolds and mutations. Bioorganic & Medicinal Chemistry. 2012, 20 (10): 3150-3161.
[3] Debasis Dasa, Jian Honga, Shu-Hui Chena, et al. Recent advances in drug discovery of benzothiadiazine and related analogs as HCV NS5B polymerase inhibitors. Bioorganic & Medicinal Chemistry. 2011, 19(16): 4690-4703
[4] Pierre L Beaulieu. Recent advances in the development of NS5B polymerase inhibitors for the treatment of hepatitis C virus infection. Informahealthcare. 2009, 19(2): 145-164
[5] Safety,Tolerability and Pharmacokinetics of Multiple Ascending Doses of VCH 916 in Subjects With Chronic Hep C Infection

VCH-916 Preparation Products And Raw materials

Raw materials

Preparation Products

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VCH-916 Suppliers

China 49 United States 8 Global 57

NCE Biomedical Co.,Ltd.

Tel: 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Fax: +86-27-87599188
Country: China
ProdList: 1493
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Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

ShangHai Onsyn-Chemical Technology Co., Ltd.

Tel: 13917628136 15900795984
Fax: +86-21-58359326
Email: 572350448@qq.com
Country: China
ProdList: 255
Advantage: 55

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2990
Advantage: 60

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

SPIRO PHARMA

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Email: eric_feng1954@126.com
Country: China
ProdList: 9248
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Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
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Guangzhou QiYun Biotechnology Co., Ltd.

Tel: 020-61288194 61288195
Fax: 020-61288700
Email: 505721671@qq.com
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ProdList: 3866
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Lancrix Chemicals

Tel: 86-21-50817262
Fax: 86-21-57712035
Email: sales@lancrix.com
Country: China
ProdList: 1502
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1200133-34-1, VCH-916Related Search:

VCH-916

5-(1-Cyclohexen-1-yl)-3-[(trans-4-methoxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino]-2-thiophenecarboxylic acid potassium salt

VCH-916, >=98%

potassiuM 5-cyclohexenyl-3-(N-((1r,4r)-4-Methoxycyclohexyl)-4-MethylcyclohexanecarboxaMido)thiophene-2-carboxylate

VCH 916;VCH916

CS-790

VCH-916 (Free)

HCV,VCH 916,VCH916,Hepatitis C virus,VCH-916,inhibit,Inhibitor

Potassium 5-(cyclohex-1-en-1-yl)-3-(trans-N-(trans-4-methoxycyclohexyl)-4-methylcyclohexane-1-carboxamido)thiophene-2-carboxylate

1200133-34-1

C26H36NO4SK

C26H36KNO4S