3-Bromo-5-methoxyphenol
- Product Name
- 3-Bromo-5-methoxyphenol
- CAS No.
- 855400-66-7
- Chemical Name
- 3-Bromo-5-methoxyphenol
- Synonyms
- 855400-66-7;3-Bromo-5-methoxyphenol;Phenol, 3-bromo-5-methoxy-;3-Bromo-5-methoxyphenol 97%;3-hydroxy-5-methoxybromobenzene
- CBNumber
- CB82513232
- Molecular Formula
- C7H7BrO2
- Formula Weight
- 203.03
- MOL File
- 855400-66-7.mol
3-Bromo-5-methoxyphenol Property
- Melting point:
- 102 °C
- Boiling point:
- 277.4±20.0 °C(Predicted)
- Density
- 1.585±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 8.63±0.10(Predicted)
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2909500090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- B696778
- Product name
- 3-Bromo-5-methoxyphenol
- Packaging
- 25mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B696778
- Product name
- 3-Bromo-5-methoxyphenol
- Packaging
- 250mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- HCH0030321
- Product name
- 3-BROMO-5-METHOXYPHENOL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $497.1
- Updated
- 2021/12/16
- Product number
- V8110
- Product name
- 3-Bromo-5-methoxyphenol
- Packaging
- 5g
- Price
- $870
- Updated
- 2021/12/16
- Product number
- A269802
- Product name
- 3-Bromo-5-methoxyphenol
- Purity
- 97%
- Packaging
- 100mg
- Price
- $42
- Updated
- 2021/12/16
3-Bromo-5-methoxyphenol Chemical Properties,Usage,Production
Synthesis
20469-65-2
855400-66-7
(1a) Synthesis of 3-bromo-5-methoxyphenol: Commercially available 1-bromo-3,5-dimethoxybenzene (18.74 g, 86.3 mmol) was dissolved in 1-methyl-2-pyrrolidinone (100 mL), and sodium methanethiol (6.74 g, 96.2 mmol) was added. The reaction mixture was stirred at 100 °C for 3 h under nitrogen protection. After completion of the reaction, the reaction solution was cooled to room temperature, acidified by adding 1N hydrochloric acid (200 mL) and extracted with ether (500 mL). The organic layer was washed with saturated brine and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure and the resulting residue was purified by silica gel column chromatography (eluent: ethyl acetate/hexane, 20%-25% gradient) to afford the target compound 3-bromo-5-methoxyphenol (15.03 g, 86% yield) as a white solid.1H-NMR (CDCl3, 400 MHz) δ: 3.77 (3H, s), 4.82 (1H, s), 6.33 (1H, s), 6.33 (1H, s). 6.33 (1H, t, J = 2.4 Hz), 6.61 (1H, t, J = 2.0 Hz), 6.66 (1H, t, J = 2.0 Hz).
References
[1] Patent: EP2239253, 2010, A1. Location in patent: Page/Page column 44
[2] European Journal of Organic Chemistry, 2016, vol. 2016, # 3, p. 426 - 429
[3] Tetrahedron Letters, 2018, vol. 59, # 17, p. 1670 - 1673
[4] Patent: WO2007/34325, 2007, A1. Location in patent: Page/Page column 68
[5] Patent: US2011/105562, 2011, A1. Location in patent: Page/Page column 18
3-Bromo-5-methoxyphenol Preparation Products And Raw materials
Raw materials
Preparation Products
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