(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one

Product Name: (E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one
CAS No.: 347323-96-0
Chemical Name: (E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one
Synonyms: ITX 3;CS-1227;ITX3,ITX-3;ITX3 >=98% (HPLC);Trio N-Terminal RhoGEF Domain Inhibitor, ITX3;Trio N-Terminal RhoGEF Domain Inhibitor, ITX3 - CAS 347323-96-0 - Calbiochem;2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]-thiazolo[3,2-a]benzimidazol-3(2H)-one;Thiazolo[3,2-a]benzimidazol-3(2H)-one, 2-[(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]-;2-((2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene)benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-one;(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one
CBNumber: CB82518888
Molecular Formula: C22H17N3OS
Formula Weight: 371.45
MOL File: 347323-96-0.mol

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(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one Property

Boiling point:: 589.5±60.0 °C(Predicted)
Density: 1.32±0.1 g/cm3(Predicted)
storage temp.: Store at +4°C
solubility: DMSO: ≥4mg/mL
form: Yellow solid
pka: 0.17±0.20(Predicted)
color: Light yellow to yellow

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: I1411
Product name: ITX3
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $108
Updated: 2024/03/01

Sigma-Aldrich

Product number: 645890
Product name: Trio N-Terminal RhoGEF Domain Inhibitor, ITX3
Packaging: 10mg
Price: $159
Updated: 2024/03/01

Sigma-Aldrich

Product number: I1411
Product name: ITX3
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $322
Updated: 2024/03/01

Tocris

Product number: 3792
Product name: ITX3
Purity: ≥99%(HPLC)
Packaging: 10
Price: $177
Updated: 2021/12/16

Tocris

Product number: 3792
Product name: ITX3
Purity: ≥99%(HPLC)
Packaging: 50
Price: $745
Updated: 2021/12/16

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(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one Chemical Properties,Usage,Production

Uses

ITX3 is a nontoxic inhibitor of TrioN, the N-terminal GEF domain of the multidomain Trio protein. ITX 3 specifically inhibited endogenous TrioN activity.

(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

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(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one Suppliers

China 32 United Kingdom 1 United States 9 Global 42

Tocris Bioscience

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347323-96-0, (E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-oneRelated Search:

(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one

ITX 3

2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]-thiazolo[3,2-a]benzimidazol-3(2H)-one

Trio N-Terminal RhoGEF Domain Inhibitor, ITX3

CS-1227

Trio N-Terminal RhoGEF Domain Inhibitor, ITX3 - CAS 347323-96-0 - Calbiochem

Thiazolo[3,2-a]benzimidazol-3(2H)-one, 2-[(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]-

ITX3 >=98% (HPLC)

ITX3,ITX-3

2-((2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene)benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-one

347323-96-0