ChemicalBook > CAS DataBase List > N-(4-Ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide

N-(4-Ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide

Product Name
N-(4-Ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide
CAS No.
443292-81-7
Chemical Name
N-(4-Ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide
Synonyms
SF 11;SID 17507305;SF-11 >=98% (HPLC);N-(4-ethoxyphenyl)-4-(hydroxydiphenylMethyl)piperidine-1-carbothioaMide;N-(4-Ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide;1-Piperidinecarbothioamide, N-(4-ethoxyphenyl)-4-(hydroxydiphenylmethyl)-
CBNumber
CB82518909
Molecular Formula
C27H30N2O2S
Formula Weight
446.6
MOL File
443292-81-7.mol
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N-(4-Ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide Property

storage temp. 
Store at +4°C
solubility 
DMSO: ≥20mg/mL
form 
powder
color 
white to off-white
InChI
1S/C27H30N2O2S/c1-2-31-25-15-13-24(14-16-25)28-26(32)29-19-17-23(18-20-29)27(30,21-9-5-3-6-10-21)22-11-7-4-8-12-22/h3-16,23,30H,2,17-20H2,1H3,(H,28,32)
InChIKey
PMEQBGAGFZDWQX-UHFFFAOYSA-N
SMILES
CCOc1ccc(NC(=S)N2CCC(CC2)C(O)(c3ccccc3)c4ccccc4)cc1
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Safety

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
26
WGK Germany 
3
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S6701
Product name
SF-11
Purity
≥98% (HPLC)
Packaging
5mg
Price
$126
Updated
2025/07/31
Sigma-Aldrich
Product number
S6701
Product name
SF-11
Purity
≥98% (HPLC)
Packaging
25mg
Price
$509
Updated
2025/07/31
Tocris
Product number
3898
Product name
SF11
Purity
≥99%(HPLC)
Packaging
10
Price
$224
Updated
2021/12/16
Tocris
Product number
3898
Product name
SF11
Purity
≥99%(HPLC)
Packaging
50
Price
$942
Updated
2021/12/16
Usbiological
Product number
256653
Product name
SF 11
Packaging
10mg
Price
$480
Updated
2021/12/16
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N-(4-Ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide Chemical Properties,Usage,Production

Uses

SF 11 is a selective brain penetrant neuropeptide Y Y2 receptor antagonist.

Definition

ChEBI: N-(4-ethoxyphenyl)-4-[hydroxy(diphenyl)methyl]-1-piperidinecarbothioamide is a diarylmethane.

Biological Activity

Radioligand studies reveal th at SF-11 also targets 5-HT2B and dopamine transporter.1', 'SF-11 is a potent, selective NPY Y2 receptor antagonist; brain-penetrant.

IC 50

NPY Y2 receptor: 199 nM (IC50)

storage

Store at +4°C

N-(4-Ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(4-Ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide Suppliers

China 26 United Kingdom 1 United States 7 Global 34
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
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86-21-50328109
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3bsc@sina.com
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China
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EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
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United States
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Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627
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021-65675885
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info@efebio.com
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China
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Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
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QQ:3008007432
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3008007409@qq.com
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China
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MQ (shanghai) Pharmaceuticals Co., Ltd.
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13761635123
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1014988033@qq
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sales@linyuepharm.com
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China
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TargetMol Chemicals Inc.
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+1-781-999-5354; +17819995354
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marketing@targetmol.com
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United States
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Energy Chemical
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021-58432009 400-005-6266
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021-58436166
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marketing@energy-chemical.com
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China
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Jinan Jiuli Biotechnology Co. , Ltd.
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15865264761
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486064515@qq.com
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China
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TargetMol Chemicals Inc.
Tel
4008200310
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marketing@tsbiochem.com
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China
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Shanghai Aladdin Biochemical Technology Co.,Ltd.
Tel
400-6206333 13167063860
Email
anhua.mao@aladdin-e.com
Country
China
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48550
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443292-81-7, N-(4-Ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamideRelated Search:


  • N-(4-Ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide
  • SF 11
  • N-(4-ethoxyphenyl)-4-(hydroxydiphenylMethyl)piperidine-1-carbothioaMide
  • SID 17507305
  • 1-Piperidinecarbothioamide, N-(4-ethoxyphenyl)-4-(hydroxydiphenylmethyl)-
  • SF-11 >=98% (HPLC)
  • 443292-81-7