ChemicalBook > CAS DataBase List > Paliperidone Palmitate

Paliperidone Palmitate

Product Name
Paliperidone Palmitate
CAS No.
199739-10-1
Chemical Name
Paliperidone Palmitate
Synonyms
Invega Sustenna;RO 92670;Paliperidone Palmitate;Paliperidone Palmitate-d31;Paliperidone Palmitate [USAN];9-Hydroxyrisperidone palmitate;Paliperidone Palmitate USP/EP/BP;Paliperidone Palmitate Benzisoxazole Impurity;Paliperidone Impurity 39 (Paliperidone Palmitate);3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-9-yl palmitate
CBNumber
CB82519012
Molecular Formula
C39H57FN4O4
Formula Weight
664.89
MOL File
199739-10-1.mol
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Paliperidone Palmitate Property

Melting point:
110-115°C
Boiling point:
736.3±70.0 °C(Predicted)
Density 
1.19
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly, Heated, Sonicated), Methanol (Slightly)
form 
Solid
pka
8.07±0.10(Predicted)
color 
Off-White to Light Beige
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
P141020
Product name
PaliperidonePalmitate
Packaging
500mg
Price
$210
Updated
2021/12/16
Activate Scientific
Product number
AS148096
Product name
PaliperidonePalmitate
Purity
98%
Packaging
250mg
Price
$233
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0027470
Product name
PALIPERIDONE PALMITATE
Purity
95.00%
Packaging
25MG
Price
$750.75
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0027470
Product name
PALIPERIDONE PALMITATE
Purity
95.00%
Packaging
250MG
Price
$1963.5
Updated
2021/12/16
ChemScene
Product number
CS-0016387
Product name
Paliperidonepalmitate
Purity
98.16%
Packaging
10mg
Price
$70
Updated
2021/12/16
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Paliperidone Palmitate Chemical Properties,Usage,Production

Description

Paliperidone palmitate is an atypical long acting antipsychotics，which can fast onset in acute phase and continuously improve the symptoms in maintenance phase． It has the solid efficacy and convenient ad[1]ministration，which offer a new option for schizophrenia treatment and will help patients to adhere the treatment and prevent relapse． As the sole long acting antipsychotics with monthly injection，it was approved by CFDA in 2011 and indicated for the acute and maintenance treatment of schizophrenia．

Uses

Paliperidone Palmitate is a long-acting injectable atypical antipsychotic used in the treatment of schizophrenia.

Definition

ChEBI: 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-4-oxo-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-9-yl hexadecanoate is a fatty acid ester obtained by the formal condensation of the carboxy group of hexadecanoic acid with the hydroxy group of 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one. It is a member of 1,2-benzoxazoles, a heteroarylpiperidine, an organofluorine compound, a pyridopyrimidine and a fatty acid ester.

Side effects

The review of the literature also underlined that paliperidone palmitate is well tolerated, compared with placebo. Frequency and severity of side-effects such as extrapyramidal symptoms, hyperprolactinemia and weight gain, was similar or less than those found in treatment with other atypical antipsychotics, including long-acting ones.

Paliperidone Palmitate Preparation Products And Raw materials

Raw materials

Preparation Products

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Paliperidone Palmitate Suppliers

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View Lastest Price from Paliperidone Palmitate manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd
Product
Paliperidone Palmitate 199739-10-1
Price
US $70.00-700.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-11-20
Sinoway Industrial co., ltd.
Product
Paliperidone Palmitate 199739-10-1
Price
US $175.00-85.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
0.99
Supply Ability
20 tons
Release date
2023-12-05
Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
Paliperidone Palmitate 199739-10-1
Price
US $50.00/kg
Min. Order
1kg
Purity
99.10%
Supply Ability
50000kg
Release date
2024-04-22

199739-10-1, Paliperidone PalmitateRelated Search:

3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-9-hydroxy-2-methylpyrido[1,2-a]pyrimidin-4-one Paliperidone E-Oxime Isooctyl palmitate Clindamycin palmitate hydrochloride Paliperidone Paliperidone Impurity 4 2,4-Difluorophenyl-(4-piperidinyl)methanone oxime hydrochloride Isopropyl palmitate Ethylhexyl Palmitate Clindamycin palmitate hydrochloride Vitamin A palmitate PALMITELAIDIC ACID Paliperidone N-Oxide 9-hydroxy-2-methyl-3-vinyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one (R)-9-Hydroxy Risperidone (S)-9-Hydroxy Risperidone 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one RAC 9-HYDROXYRISPERIDONE-D4

  • (9RS)-3-(2-(4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl)et hyl)-2-Methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido(1,2-a)pyriMi din-9-yl hexadecanoate
  • Hexadecanoic acid 3-[2-[4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl]-ethyl]-6,7,8,9-tetrahydro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl ester
  • Paliperidone Palmitate
  • Paliperidone Palmitate [USAN]
  • Invega Sustenna
  • RO 92670
  • 9-Hydroxyrisperidone palmitate
  • Hexadecanoic acid 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl ester
  • Paliperidone Palmitate-d31
  • Paliperidone Impurity 39 (Paliperidone Palmitate)
  • 3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-9-yl palmitate
  • Paliperidone Palmitate USP/EP/BP
  • Paliperidone palmitateQ: What is Paliperidone palmitate Q: What is the CAS Number of Paliperidone palmitate Q: What is the storage condition of Paliperidone palmitate Q: What are the applications of Paliperidone palmitate
  • Paliperidone Palmitate Benzisoxazole Impurity
  • 199739-10-1
  • C39H57FN4O4
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • API