1H-Indazole-6-carboxylic acid, 4-bromo-
- Product Name
- 1H-Indazole-6-carboxylic acid, 4-bromo-
- CAS No.
- 885523-43-3
- Chemical Name
- 1H-Indazole-6-carboxylic acid, 4-bromo-
- Synonyms
- 4-Bromo-6-indazolecarboxylic acid;4-BroMo-1H-indazole-6-carboxylic acid;1H-Indazole-6-carboxylicacid,4-broMo-
- CBNumber
- CB82525204
- Molecular Formula
- C8H5BrN2O2
- Formula Weight
- 241.04
- MOL File
- 885523-43-3.mol
1H-Indazole-6-carboxylic acid, 4-bromo- Property
- Density
- 1.946
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- Light yellow to yellow Solid
Safety
- RIDADR
- UN2811
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H317May cause an allergic skin reaction
H319Causes serious eye irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 3H21-9-02
- Product name
- 4-Bromo-1H-indazole-6-carboxylicacid
- Packaging
- 1g
- Price
- $225
- Updated
- 2021/12/16
- Product number
- Z5270
- Product name
- 4-Bromo-1H-indazole-6-carboxylicacid
- Packaging
- 5g
- Price
- $277
- Updated
- 2021/12/16
- Product number
- 068829
- Product name
- 4-Bromo-6-(1H)-indazole carboxylic acid
- Purity
- >95%
- Packaging
- 250mg
- Price
- $605
- Updated
- 2021/12/16
- Product number
- 3H21-9-02
- Product name
- 4-Bromo-1H-indazole-6-carboxylicacid
- Packaging
- 5G
- Price
- $750
- Updated
- 2021/12/16
- Product number
- 068829
- Product name
- 4-Bromo-6-(1H)-indazole carboxylic acid
- Purity
- >95%
- Packaging
- 500mg
- Price
- $1000
- Updated
- 2021/12/16
1H-Indazole-6-carboxylic acid, 4-bromo- Chemical Properties,Usage,Production
Synthesis
885518-47-8
885523-43-3
4.2.2 Synthesis of 4-bromo-1H-indazole-6-carboxylic acid (14): 4-bromo-indazole-6-carboxylic acid methyl ester (13) (3.38 g, 13.3 mmol) was dissolved in ethanol (30 mL) and 15% aqueous sodium hydroxide solution (15 mL) was added. The reaction mixture was stirred at room temperature for 4 hours. After completion of the reaction, the solvent was removed by concentration under reduced pressure. The residue was diluted with water and acidified to pH 4 with 1 M hydrochloric acid to precipitate an orange precipitate. The precipitate was collected by filtration and dried under vacuum to give 4-bromo-1H-indazole-6-carboxylic acid (14) (2.64 g, 83%) as a light orange solid. Thin layer chromatography (TLC) Rf value (10% MeOH/CH2Cl2): 0.10. Melting point: 294-296 °C (decomposition).1H NMR (DMSO-d6, δ): 13.78 (1H, broad single peak), 13.3 (1H, broad single peak), 8.15 (2H, single peak), 7.80 (1H, double peak, J = 0.5 Hz).13C NMR (DMSO-d6, δ): 166.4, 139.9, 133.4, 129.9, 125.7, 123.0, 113.0, 111.8. mass spectra (ESI): m/z 240.9 ([M(79Br)+H]+), 242.9 ([M(81Br)+H]+). High Resolution Mass Spectrometry (HRMS, ESI): [M(79Br)+H]+ calculated value 240.9613 (C8H6BrN2O2), measured value 240.9607.
References
[1] Tetrahedron, 2014, vol. 70, # 2, p. 318 - 326
[2] Patent: WO2011/38579, 2011, A1. Location in patent: Page/Page column 35; 36
1H-Indazole-6-carboxylic acid, 4-bromo- Preparation Products And Raw materials
Raw materials
Preparation Products
1H-Indazole-6-carboxylic acid, 4-bromo- Suppliers
- Tel
- 001-857-928-2050 or 1-888-588-9418
- Fax
- 001-617-206-9595
- sales@chemreagents.com
- Country
- United States
- ProdList
- 10186
- Advantage
- 62
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 18270980682
- Fax
- 021 51613951
- mlcheng@sunwaypharm.cn
- Country
- China
- ProdList
- 8669
- Advantage
- 57
- Tel
- 18986259541
- Fax
- 027-87840182
- sales@3stc.com
- Country
- China
- ProdList
- 3763
- Advantage
- 58
- Tel
- 021-50718719 13918719472
- Fax
- 021-50718719
- Country
- China
- ProdList
- 979
- Advantage
- 58
- Tel
- +86057186818502 13588463833
- Fax
- Pls mail us for more information!
- info@sagechem.com
- Country
- China
- ProdList
- 10266
- Advantage
- 58
- Tel
- 027-86697669 13986148687
- Fax
- 86-027-86697669
- sales@tcaschem.com
- Country
- China
- ProdList
- 3991
- Advantage
- 55
- Tel
- 027-027-87342388 18086026008
- Fax
- 027-87342388
- sales@kaymke.com
- Country
- China
- ProdList
- 3731
- Advantage
- 55
- Tel
- 027-65318838 13646286950
- sales@devinchem.com
- Country
- China
- ProdList
- 2953
- Advantage
- 58
- Tel
- 021-57171705 13817537615
- Fax
- QQ3095748324
- sales@run-biotech.com
- Country
- China
- ProdList
- 2337
- Advantage
- 58
View Lastest Price from 1H-Indazole-6-carboxylic acid, 4-bromo- manufacturers
- Product
- 4-Bromo-1H-indazole-6-carboxylic acid 885523-43-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2018-08-15