N-[2-[[(1S)-2'-(3-Methylbutoxy)[1,1'-binaphthalen]-2-yl]oxy]acetyl]-D-lysyl-D-arginyl-L-leucine 3-methylbutyl ester hydrochloride
- Product Name
- N-[2-[[(1S)-2'-(3-Methylbutoxy)[1,1'-binaphthalen]-2-yl]oxy]acetyl]-D-lysyl-D-arginyl-L-leucine 3-methylbutyl ester hydrochloride
- CAS No.
- 900814-48-4
- Chemical Name
- N-[2-[[(1S)-2'-(3-Methylbutoxy)[1,1'-binaphthalen]-2-yl]oxy]acetyl]-D-lysyl-D-arginyl-L-leucine 3-methylbutyl ester hydrochloride
- Synonyms
- CS-879;CS-1218;AVX 13616;Isopentyl (2-(((S)-2'-(isopentyloxy)-[1,1'-binaphthalen]-2-yl)oxy)acetyl)-D-lysyl-D-arginyl-L-leucinate dihydrochloride;N-[2-[[(1S)-2'-(3-Methylbutoxy)[1,1'-binaphthalen]-2-yl]oxy]acetyl]-D-lysyl-D-arginyl-L-leucine 3-methylbutyl ester hydrochloride;N-[2-[[(1S)-2'-(3-Methylbutoxy)[1,1'-binaphthalen]-2-yl]oxy]acetyl]-D-lysyl-D-arginyl-L-leucine 3-methylbutyl ester hydrochloride USP/EP/BP
- CBNumber
- CB82534811
- Molecular Formula
- C50H71N7O7.2(HCl)
- Formula Weight
- 919
- MOL File
- 900814-48-4.mol
N-[2-[[(1S)-2'-(3-Methylbutoxy)[1,1'-binaphthalen]-2-yl]oxy]acetyl]-D-lysyl-D-arginyl-L-leucine 3-methylbutyl ester hydrochloride Property
- storage temp.
- Store at -20°C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
N-Bromosuccinimide Price
- Product number
- CD31000349
- Product name
- AVX13616
- Purity
- 98+%
- Packaging
- 5mg
- Price
- $245
- Updated
- 2021/12/16
- Product number
- CD31000349
- Product name
- AVX13616
- Purity
- 98+%
- Packaging
- 10mg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- CD31000349
- Product name
- AVX13616
- Purity
- 98+%
- Packaging
- 50mg
- Price
- $1050
- Updated
- 2021/12/16
- Product number
- CM141629
- Product name
- isopentyl(2-(((S)-2''-(isopentyloxy)-[1,1''-binaphthalen]-2-yl)oxy)acetyl)-D-lysyl-D-arginyl-L-leucinatedihydrochloride
- Purity
- 98%
- Packaging
- 100mg
- Price
- $1374
- Updated
- 2021/12/16
- Product number
- CD31000349
- Product name
- AVX13616
- Purity
- 98+%
- Packaging
- 100mg
- Price
- $1470
- Updated
- 2021/12/16
N-[2-[[(1S)-2'-(3-Methylbutoxy)[1,1'-binaphthalen]-2-yl]oxy]acetyl]-D-lysyl-D-arginyl-L-leucine 3-methylbutyl ester hydrochloride Chemical Properties,Usage,Production
Uses
AVX 13616 shows the potent in vivo antibacterial activity of Avexa’s lead antibacterial candidate; particularly against drug-resistant Staphylococcus pathogens. IC50 value: 2-4 ug/ml (MICs) Target: antibacterial agent AVX13616 was as active as mupirocin in a nasal decolonization model but required only a single application. The compounds are being developed for topical indications and/or wound infection/catheter-related infections. AVX13616 and other compounds showed broad spectrum antibacterial activity against a range of isolates with MICs of 2-4 micrograms per millilitre against S. aureus, coagulase negative staphylococci, enterococci, MRSA, VISA and VRSA. A single application of 5% (w/w) AVX13616 (approximately equimolar to 2% mupirocin) was as effective as 2% mupirocin administered twice a day for five days in nasal decolonisation of MRSA in mice.
References
[1] Avexa Presents Data from Apricitabine and Antibacterial Programs at two International Conferences
N-[2-[[(1S)-2'-(3-Methylbutoxy)[1,1'-binaphthalen]-2-yl]oxy]acetyl]-D-lysyl-D-arginyl-L-leucine 3-methylbutyl ester hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
N-[2-[[(1S)-2'-(3-Methylbutoxy)[1,1'-binaphthalen]-2-yl]oxy]acetyl]-D-lysyl-D-arginyl-L-leucine 3-methylbutyl ester hydrochloride Suppliers
- Tel
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- Fax
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- sales@seqchem.com
- Country
- United Kingdom
- ProdList
- 3113
- Advantage
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