ChemicalBook > CAS DataBase List > A 1120

A 1120

Product Name
A 1120
CAS No.
1152782-19-8
Chemical Name
A 1120
Synonyms
A 1120;A 1120, 10 mM in DMSO;A-1120,Inhibitor,inhibit,A 1120,A1120;2-(4-(2-(trifluoromethyl)phenyl)piperidine-1-carboxamido)benzoic acid;2-({4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl}amino)benzoic acid;Benzoic acid, 2-[[[4-[2-(trifluoromethyl)phenyl]-1-piperidinyl]carbonyl]amino]-
CBNumber
CB82535656
Molecular Formula
C20H19F3N2O3
Formula Weight
392.37
MOL File
1152782-19-8.mol
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A 1120 Property

Boiling point:
572.3±50.0 °C(Predicted)
Density 
1.370±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
DMSO: 100 mM; Ethanol: 25 mM
form 
powder
pka
4.03±0.36(Predicted)
color 
off-white
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Safety

Hazard Codes 
Xn,N
Risk Statements 
22-36-43-50/53
Safety Statements 
26-36/37-60-61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A3111
Product name
A1120
Purity
≥98% (HPLC), powder
Packaging
5mg
Price
$99.5
Updated
2025/07/31
Sigma-Aldrich
Product number
A3111
Product name
A1120
Purity
≥98% (HPLC), powder
Packaging
25mg
Price
$492
Updated
2025/07/31
Tocris
Product number
3793
Product name
A1120
Purity
≥99%(HPLC)
Packaging
10
Price
$186
Updated
2021/12/16
Tocris
Product number
3793
Product name
A1120
Purity
≥99%(HPLC)
Packaging
50
Price
$785
Updated
2021/12/16
TRC
Product number
A965350
Product name
A1120
Packaging
2.5mg
Price
$220
Updated
2021/12/16
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A 1120 Chemical Properties,Usage,Production

Uses

A 1120 is a a nonretinoid RBP4 antagonist, which inhibits formation of cytotoxic bisretinoids in the animal model of enhanced retinal lipofuscinogenesis.

Biochem/physiol Actions

A1120 is a selective non-retinoid ligand for retinol-binding protein 4 (RBP4). RBP4 transports retinol from the liver to extrahepatic tissues and RBP4 lowering is reported to improve insulin sensitivity in mice. A1120 is a high affinity non-retinoid ligand for RBP4 which disrupts the interaction between RBP4 and its binding partner transthyretin (TTR). It binds to the same site as retinol and induces changes in the orientation (compared to the retinol bound form) of loops at the RBP4-TTR interaction interface.A1120 lowers RBP4 and retinol levels in a dose-dependent manner, to a similar extent as seen with fenretinide. However, unlike fenretinide (Sigma# H7779), A1120 does not have beneficial effects on insulin resistance.

storage

Store at RT

A 1120 Preparation Products And Raw materials

Raw materials

Preparation Products

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A 1120 Suppliers

China 47 United Kingdom 1 United States 11 Global 59
Nanjing Dulai Biotechnology Co., Ltd.
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Career Henan Chemica Co
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Henan Weituxi Chemical Technology Co., Ltd.
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Bide Pharmatech Ltd.
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Santa Cruz Biotechnology Inc
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Neobioscience Co., Ltd.
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Absin Bioscience Inc.
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View Lastest Price from A 1120 manufacturers

Career Henan Chemica Co
Product
A 1120 1152782-19-8
Price
US $0.80-1.80/KG
Min. Order
1KG
Purity
95%~99.99%
Supply Ability
10 MT/ Month
Release date
2020-11-04

1152782-19-8, A 1120Related Search:


  • A 1120
  • 2-(4-(2-(trifluoromethyl)phenyl)piperidine-1-carboxamido)benzoic acid
  • Benzoic acid, 2-[[[4-[2-(trifluoromethyl)phenyl]-1-piperidinyl]carbonyl]amino]-
  • A-1120,Inhibitor,inhibit,A 1120,A1120
  • 2-({4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl}amino)benzoic acid
  • A 1120, 10 mM in DMSO
  • 1152782-19-8