2-chloro-6-methoxypyridin-4-amine

Product Name: 2-chloro-6-methoxypyridin-4-amine
CAS No.: 1008304-85-5
Chemical Name: 2-chloro-6-methoxypyridin-4-amine
Synonyms: 2-chloro-6-methoxypyridin-4-amine;2-Chloro-6-methoxy-4-pyridinamine;4-Pyridinamine, 2-chloro-6-methoxy-
CBNumber: CB82538394
Molecular Formula: C6H7ClN2O
Formula Weight: 158.59
MOL File: 1008304-85-5.mol

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2-chloro-6-methoxypyridin-4-amine Property

storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
Appearance: Light yellow to light brown Solid

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: C369863
Product name: 2-Chloro-6-methoxypyridin-4-amine
Packaging: 100mg
Price: $265
Updated: 2021/12/16

Apolloscientific

Product number: OR945855
Product name: 2-Chloro-6-methoxypyridin-4-amine
Purity: 95+%
Packaging: 250mg
Price: $73
Updated: 2021/12/16

Matrix Scientific

Product number: 126859
Product name: 2-Chloro-6-methoxypyridin-4-amine
Purity: >95%
Packaging: 1g
Price: $1224
Updated: 2021/12/16

AK Scientific

Product number: 4485DU
Product name: 2-Chloro-6-methoxypyridin-4-amine
Packaging: 5g
Price: $1427
Updated: 2021/12/16

AK Scientific

Product number: 4485DU
Product name: 2-Chloro-6-methoxypyridin-4-amine
Packaging: 10g
Price: $2373
Updated: 2021/12/16

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2-chloro-6-methoxypyridin-4-amine Chemical Properties,Usage,Production

Synthesis

67-56-1

2587-02-2

1008304-85-5

General procedure for the synthesis of 2-chloro-6-methoxypyridin-4-amine from methanol and 4-amino-2,6-dichloropyridine: 2,6-dichloropyridin-4-amine (41.6.A, purchased from Aldrich, 3.10 g, 19.0 mmol) was dissolved in 20% NaOMe/MeOH solution (15 mL), and the reaction was carried out at reflux for 72 hours. After completion of the reaction, the reaction mixture was diluted with H2O (40 mL) and extracted with 30% iPrOH/CHCl3 (3 × 30 mL). The organic layers were combined and washed sequentially with water (2 × 20 mL) and brine (15 mL), then dried with MgSO4. After removal of the organic solvent under reduced pressure, the residue was purified by rapid chromatography on silica gel with 0-10% MeOH/CH2Cl2 as eluent to afford the target product 2-chloro-6-methoxypyridin-4-amine (41.6.B) as a white solid (2.45 g, 81.2% yield).

References

[1] Patent: WO2010/93849, 2010, A2. Location in patent: Page/Page column 126
[2] Patent: WO2013/87805, 2013, A1. Location in patent: Page/Page column 74; 75; 76
[3] Patent: US2013/158042, 2013, A1. Location in patent: Paragraph 0471; 0472; 0473; 0487; 0488; 0489; 0490; 0491

2-chloro-6-methoxypyridin-4-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-chloro-6-methoxypyridin-4-amine Suppliers

China 85 India 1 United States 5 Global 91

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1008304-85-5, 2-chloro-6-methoxypyridin-4-amineRelated Search:

2-chloro-6-methoxypyridin-4-amine

4-Pyridinamine, 2-chloro-6-methoxy-

2-Chloro-6-methoxy-4-pyridinamine

1008304-85-5