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FIPI

Product Name
FIPI
CAS No.
939055-18-2
Chemical Name
FIPI
Synonyms
FIPI;CS-1511;Vitamin B5 Monomer;FIPI HYDROCHLORIDE;FIPI, 10 mM in DMSO;5-Fluoro-2-Indolyl des-Chlorohalopemide;FIPI (5-Fluoro-2-indolyl deschlorohalopemide); 5-fluoro-N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]-1H-indole-2-carboxamide;N-[2-[4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-5-fluoro-1H-indole-2-carboxamide;1H-Indole-2-carboxamide, N-[2-[4-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-5-fluoro-
CBNumber
CB82550798
Molecular Formula
C23H24FN5O2
Formula Weight
421.47
MOL File
939055-18-2.mol
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FIPI Property

Density 
1.349±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : 14.67 mg/mL (34.81 mM; Need ultrasonic and warming)
form 
Powder
pka
12.04±0.30(Predicted)
color 
Light yellow to khaki
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
528245
Product name
PLD Inhibitor, FIPI
Purity
The PLD Inhibitor, FIPI controls the biological activity of PLD. This small molecule/inhibitor is primarily used for Membrane applications.
Packaging
5 mg
Price
$192
Updated
2025/07/31
Cayman Chemical
Product number
13563
Product name
FIPI
Purity
≥98%
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
13563
Product name
FIPI
Purity
≥98%
Packaging
5mg
Price
$130
Updated
2024/03/01
Cayman Chemical
Product number
13563
Product name
FIPI
Purity
≥98%
Packaging
10mg
Price
$235
Updated
2024/03/01
Cayman Chemical
Product number
13563
Product name
FIPI
Purity
≥98%
Packaging
25mg
Price
$533
Updated
2024/03/01
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FIPI Chemical Properties,Usage,Production

Uses

FIPI is a a phospholipase D pharmacological inhibitor that alters cell spreading and inhibits chemotaxis.

Definition

ChEBI: FIPI is a member of benzimidazoles.

in vivo

FIPI (3 mg/kg; intraperitoneal injection; 2 times) shows protective effect in carotid thrombosis model and ischemic stroke model[4].

Animal Model:Ferric chloride (HY-Y0266) or transient middle cerebral artery occlusion treated mice[4]
Dosage:3 mg/kg
Administration:Intraperitoneal injection (i.p.); 2 times, 12 h apart
Result:Delayed the thrombus formation and only 3 of 9 vessels occluded during the 30-minute observation period in arterial thrombosis models.
Reduced the infarct volumes, improved motor and overall nerve function and did not impair normal hemostasis in ischemic stroke models.

IC 50

PLD1; PLD2

FIPI Preparation Products And Raw materials

Raw materials

Preparation Products

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FIPI Suppliers

China 90 The Netherlands 1 United Kingdom 2 United States 14 Global 107
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
Acesys Pharmatech
Tel
18860950986
Email
tangmanman@zenjipharma.com
Country
China
ProdList
1733
Advantage
55
AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Fax
+1 (866) 333-9607
Email
info@adooq.com
Country
United States
ProdList
2782
Advantage
58
AdooQ Bioscience CHINA
Tel
025-58849295 18951903616;
Fax
025-68650336
Email
info@adooq.cn
Country
China
ProdList
2990
Advantage
60
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4769
Advantage
55
Pharmacodia (Beijing) Co.,Ltd
Tel
+86-400-851-9921
Fax
+86-10-82826195
Email
sales@pharmacodia.com
Country
China
ProdList
2317
Advantage
55
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3866
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
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View Lastest Price from FIPI manufacturers

Career Henan Chemical Co
Product
5-fluoro-N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]-1H-indole-2-carboxamide 939055-18-2
Price
US $1.00/KG
Min. Order
1KG
Purity
Min98% HPLC
Supply Ability
g/kg/ton
Release date
2019-12-23

939055-18-2, FIPIRelated Search:


  • FIPI
  • FIPI HYDROCHLORIDE
  • 5-Fluoro-2-Indolyl des-Chlorohalopemide
  • N-[2-[4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-5-fluoro-1H-indole-2-carboxamide
  • N-[2-[4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]ethy]-5-fluoro-1H-indole-2-carboxamide hydrochloride
  • CS-1511
  • 5-fluoro-N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]-1H-indole-2-carboxamide
  • 1H-Indole-2-carboxamide, N-[2-[4-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-5-fluoro-
  • Vitamin B5 Monomer
  • FIPI, 10 mM in DMSO
  • FIPI (5-Fluoro-2-indolyl deschlorohalopemide)
  • 939055-18-2