4-Amino-6-chloro-5-fluoropyrimidine

Product Name: 4-Amino-6-chloro-5-fluoropyrimidine
CAS No.: 851984-15-1
Chemical Name: 4-Amino-6-chloro-5-fluoropyrimidine
Synonyms: 6-Chloro-5-fluoropyrimidin-4-amine;6-Chloro-5-fluoro-4-pyrimidinamine;4-chloro-5-fluoro-6-aminopyrimidine;5-Amino-6-chloro-5-fluoropyrimidine;4-Amino-6-chloro-5-fluoropyrimidine;6-Chloro-5-fluoropyrimidine-4-amine;4-Pyrimidinamine, 6-chloro-5-fluoro-;4-Amino-6-chloro-5-fluoropyrimidine ISO 9001：2015 REACH
CBNumber: CB82556336
Molecular Formula: C4H3ClFN3
Formula Weight: 147.54
MOL File: 851984-15-1.mol

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4-Amino-6-chloro-5-fluoropyrimidine Property

Boiling point:: 275.2±35.0℃ (760 Torr)
Density: 1.564±0.06 g/cm3 (20 ºC 760 Torr)
Flash point:: 120.3±25.9℃
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 0.27±0.10(Predicted)
Appearance: White to light yellow Solid
InChI: InChI=1S/C4H3ClFN3/c5-3-2(6)4(7)9-1-8-3/h1H,(H2,7,8,9)
InChIKey: FEIFDRDCVMVUJA-UHFFFAOYSA-N
SMILES: C1=NC(Cl)=C(F)C(N)=N1

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Safety

Safety Statements: 24/25
HazardClass: IRRITANT-HARMFUL, AVOID SKIN CONTACT
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: A603448
Product name: 4-Amino-6-chloro-5-fluoropyrimidine
Packaging: 100mg
Price: $75
Updated: 2021/12/16

Matrix Scientific

Product number: 064634
Product name: 4-Amino-6-chloro-5-fluoropyrimidine
Purity: 95%
Packaging: 5g
Price: $85
Updated: 2021/12/16

Apolloscientific

Product number: PC49628
Product name: 4-Amino-6-chloro-5-fluoropyrimidine
Packaging: 1g
Price: $90
Updated: 2021/12/16

AK Scientific

Product number: J51177
Product name: 4-Amino-6-chloro-5-fluoropyrimidine
Packaging: 10g
Price: $143
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-7-00
Product name: 4-Amino-6-chloro-5-fluoropyrimidine
Packaging: 1g
Price: $144
Updated: 2021/12/16

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4-Amino-6-chloro-5-fluoropyrimidine Chemical Properties,Usage,Production

Synthesis

213265-83-9

851984-15-1

General procedure for the synthesis of 4-amino-6-chloro-5-fluoropyrimidine from 4,6-dichloro-5-fluoropyrimidine: 4,6-dichloro-5-fluoropyrimidine (1.67 g, 10.0 mmol), n-butanol (6 mL), and 28% aqueous ammonium hydroxide (12 mL) were added to a sealed tube and mixed well. The reaction mixture was heated at 90 °C for 2 hours. After completion of the reaction, it was cooled to room temperature and the precipitated white crystals were collected by filtration to afford the target product 4-amino-6-chloro-5-fluoropyrimidine (1.31 g, 89% yield). The product was analyzed by LC-MS (ESI), m/z: 147.9 [M+H]+.

References

[1] Patent: WO2012/35039, 2012, A1. Location in patent: Page/Page column 108-109
[2] Patent: US2009/36419, 2009, A1. Location in patent: Page/Page column 44
[3] Patent: WO2013/185082, 2013, A2. Location in patent: Page/Page column 47

4-Amino-6-chloro-5-fluoropyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Amino-6-chloro-5-fluoropyrimidine Suppliers

China 93 India 3 United Kingdom 2 United States 7 Global 105

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View Lastest Price from 4-Amino-6-chloro-5-fluoropyrimidine manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 4-Amino-6-chloro-5-fluoropyrimidine 851984-15-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-26

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-Amino-6-chloro-5-fluoropyrimidine 851984-15-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-Amino-6-chloro-5-fluoropyrimidine 851984-15-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

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851984-15-1

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